NR 566 MIDTERM EXAM (
) ADVANCED
PHARMACOLOGY FOR CARE
OF THE FAMILY
[Document subtitle]
[DATE]
[COMPANY NAME]
[Company address]
,What are the major antibiotic drug classes
Beta-lactams: penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin
What is the primary goal of antibiotic therapy
kill bacteria without harming host tissue
Bactericidal antibiotics
directly kill bacteria
bacteriostatic antibiotics
Antibiotics that do not actually kill bacteria but rather inhibit bacterial proliferation while
the hosts immune system does the killing
which antibiotics are preferred for immunocompromised patients: bactericidal or
bacteriostatic
bactericidal
,which antibiotics are preferred for patients with an overwhelming infection: bactericidal
or bacteriostatic
bactericidal
broad spectrum antibiotics
affect a broad range of gram-positive or gram-negative bacteria
narrow spectrum antibiotics
Effective against specific bacteria
which is used for empiric therapy: narrow or broad
broad spectrum
Risks of Broad Spectrum
disruption of normal floral
increases risk of development of antibiotic resistance
, which antibiotics increase the risk of antibiotic resistance: narrow or broad spectrum
and why
Broad spectrum because they kill more competing organisms than narrow spectrum
drugs
is narrow or broad spectrum antibiotics preferred
narrow is preferred when possible.
broad spectrum only used when pathogen is unknown or when multiple types of
bacteria is suspected
Bactericidal drugs
Aminoglycosides
Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)
bacteriostatic drugs
clindamycin