ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING xPRACTICE
,ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
,ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
, ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
Chapter 1, The Foundation of Pharmacology: Quality and Safety
x x x x x x x x
1. A xwoman xdiagnosed xwith xobsessive–compulsive xdisorder xhas xbeen xprescribed
xoral x paroxetine xhydrochloride. xWhat x is xthe xexpected xeffect x for xthis
xprescription?
A. Curative xeffect xon xsymptoms
B. Systemic xeffect xon xsymptoms
C. Local xeffect xon xsymptoms
D. Parenteral xeffect xon xsymptoms
ANS: x xB
Rationale: xDrugs xthat xproduce xsystemic xeffects xare xtaken xinto xthe xbody, xcirculated
xthrough x the xbloodstream xto xtheir x sites xof xaction xin xvarious x body xtissues, xand
xeventually xeliminated x from xthe xbody. x Curative xagents xare xgiven xto x cure xa xdisease
xprocess. x In xthis xcase, xparoxetine x hydrochloride xwill xcontrol xthe xsymptoms xbut x not xcure
xthe xdisorder. xDrugs xwith x local xeffects, x such xas xsunscreen xand xlocal xanesthetics, xact
xmainly xat xthe xsite xof xapplication. x Paroxetine x hydrochloride x is x not xadministered
xparenterally. x Parenteral xagents xare xadministered x subcutaneously, x intramuscularly, x or
x intravenously.
PTS: 1 REF: p. x 3, xIntroduction OBJ: 1
NAT: x Client xNeeds: xPhysiological xIntegrity: xPharmacological xand xParenteral
xTherapies x TOP: Chapter: x1: xThe xFoundation xof xPharmacology: x Quality xand xSafety
KEY: x Integrated xProcess: xNursing xProcess
BLM: x x Cognitive xLevel: xUnderstand NOT: x Multiple xChoice
2. A xclient x has xbeen xprescribed xan xantibiotic. x This xmedication xis xa xnaturally xoccurring
substance xthat xhas xbeen xcheG mRicA
alDlyEm
SoBdOifOieSd.TWhaOt xM
.C is xanother xname xfor xthis xtype xof
xmedication?
A. Synthetic xdrug
B. Semisynthetic xdrug
C. Biotechnology xdrug
D. Prototype xdrug
ANS: x xB
Rationale: xSemisynthetic xdrugs x(e.g., xmany xantibiotics) xare x naturally xoccurring xsubstances
x that xhave xbeen xchemically xmodified. xSynthetic xdrugs xare xmore xstandardized x in xtheir
x chemical x characteristics, x more xconsistent x in xtheir x effects, xand xless x likely xto x produce
xallergic xreactions. x Biotechnology xdrugs xinvolve xmanipulating xDNA xand xRNA xand
xrecombining xgenes x into x hybrid x molecules xthat x can xbe x inserted xinto xliving xorganisms.
x Prototype xdrugs xare xthe xfirst x drug xof xa xparticular x group xto x be xdeveloped.
PTS: 1 REF: p. x 3, xDrug xSources OBJ: 1
NAT: x Client xNeeds: xPhysiological xIntegrity: xPharmacological xand xParenteral
xTherapies x TOP: Chapter: x1: xThe xFoundation xof xPharmacology: xQuality xand xSafety
KEY: x Integrated xProcess: xNursing xProcess
BLM: x x Cognitive xLevel: xUnderstand NOT: x Multiple xChoice
3. Which xclassification xapplies xto xmorphine?
A. Central xnervous xsystem xdepressant
B. Central xnervous xsystem xstimulant
ABRAMS' x CLINICAL xDRUG xTHERAPY: xRATIONALES xFOR xNURSING xPRACTICE
,ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
,ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
, ABRAMS' xCLINICAL xDRUG xTHERAPY: xRATIONALES xFOR x NURSING
xPRACTICE
Chapter 1, The Foundation of Pharmacology: Quality and Safety
x x x x x x x x
1. A xwoman xdiagnosed xwith xobsessive–compulsive xdisorder xhas xbeen xprescribed
xoral x paroxetine xhydrochloride. xWhat x is xthe xexpected xeffect x for xthis
xprescription?
A. Curative xeffect xon xsymptoms
B. Systemic xeffect xon xsymptoms
C. Local xeffect xon xsymptoms
D. Parenteral xeffect xon xsymptoms
ANS: x xB
Rationale: xDrugs xthat xproduce xsystemic xeffects xare xtaken xinto xthe xbody, xcirculated
xthrough x the xbloodstream xto xtheir x sites xof xaction xin xvarious x body xtissues, xand
xeventually xeliminated x from xthe xbody. x Curative xagents xare xgiven xto x cure xa xdisease
xprocess. x In xthis xcase, xparoxetine x hydrochloride xwill xcontrol xthe xsymptoms xbut x not xcure
xthe xdisorder. xDrugs xwith x local xeffects, x such xas xsunscreen xand xlocal xanesthetics, xact
xmainly xat xthe xsite xof xapplication. x Paroxetine x hydrochloride x is x not xadministered
xparenterally. x Parenteral xagents xare xadministered x subcutaneously, x intramuscularly, x or
x intravenously.
PTS: 1 REF: p. x 3, xIntroduction OBJ: 1
NAT: x Client xNeeds: xPhysiological xIntegrity: xPharmacological xand xParenteral
xTherapies x TOP: Chapter: x1: xThe xFoundation xof xPharmacology: x Quality xand xSafety
KEY: x Integrated xProcess: xNursing xProcess
BLM: x x Cognitive xLevel: xUnderstand NOT: x Multiple xChoice
2. A xclient x has xbeen xprescribed xan xantibiotic. x This xmedication xis xa xnaturally xoccurring
substance xthat xhas xbeen xcheG mRicA
alDlyEm
SoBdOifOieSd.TWhaOt xM
.C is xanother xname xfor xthis xtype xof
xmedication?
A. Synthetic xdrug
B. Semisynthetic xdrug
C. Biotechnology xdrug
D. Prototype xdrug
ANS: x xB
Rationale: xSemisynthetic xdrugs x(e.g., xmany xantibiotics) xare x naturally xoccurring xsubstances
x that xhave xbeen xchemically xmodified. xSynthetic xdrugs xare xmore xstandardized x in xtheir
x chemical x characteristics, x more xconsistent x in xtheir x effects, xand xless x likely xto x produce
xallergic xreactions. x Biotechnology xdrugs xinvolve xmanipulating xDNA xand xRNA xand
xrecombining xgenes x into x hybrid x molecules xthat x can xbe x inserted xinto xliving xorganisms.
x Prototype xdrugs xare xthe xfirst x drug xof xa xparticular x group xto x be xdeveloped.
PTS: 1 REF: p. x 3, xDrug xSources OBJ: 1
NAT: x Client xNeeds: xPhysiological xIntegrity: xPharmacological xand xParenteral
xTherapies x TOP: Chapter: x1: xThe xFoundation xof xPharmacology: xQuality xand xSafety
KEY: x Integrated xProcess: xNursing xProcess
BLM: x x Cognitive xLevel: xUnderstand NOT: x Multiple xChoice
3. Which xclassification xapplies xto xmorphine?
A. Central xnervous xsystem xdepressant
B. Central xnervous xsystem xstimulant
ABRAMS' x CLINICAL xDRUG xTHERAPY: xRATIONALES xFOR xNURSING xPRACTICE
