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1. A patient presents to an emer- YES With food or an empty stomach
gency room complaining of palpita-
tions and irregular heartbeat. The
advanced practice registered nurse
(APRN) places the patient on a car-
diac monitor and observes atrial fibril-
lation. The APRN orders dofetilide.
How should the APRN recommend this
medication be taken?
2. A 70-year-old male calls a clinic com- Do not take the nitroglycerin and call 911
plaining of chest pain that started after
having sexual activity. He took silde- Taking the medications together can cause a seri-
nafil 50 mg about eight hours ago. He ous drop in blood pressure leading to cardiovas-
has nitroglycerin 0.3 mg on hand. cular collapse.
How should the advanced practice reg-
istered nurse respond?
3. A patient diagnosed with bipolar disor- A baseline blood urea nitrogen (BUN) and crea-
der who is in a mental health clinic is tinine (CREA) level needs to be drawn to assess
discussing the possibility of beginning kidney function prior to treatment.
lithium with an advanced practice reg-
istered nurse (APRN). The patient ex- This drug can cause decreased renal function,
presses understanding and wishes to and a baseline should be drawn for future com-
proceed with treatment. The APRN ex- parison.
plains to the patient that this medica-
tion requires specific lab monitoring
and wants to draw baseline labs. The
patient asks why the test is needed.
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Which explanation should the APRN
provide to this patient?
4. An advanced practice registered nurse YES A 54-year-male with a medical history of hy-
(APRN) is reviewing the medications pertension, mild eczema, and previous history of
that will be commonly experienced a urolithiasis where all is well controlled and there
with a new nurse to determine are no current complications
whether the drugs are safe for the pa-
tients. The new nurse is given a sce-
nario where a patient is being pre-
scribed sildenafil 25 mg po prn, a pro-
totype drug for erectile dysfunction.
Which patient may take this drug safe-
ly?
5. A 30-year-old patient presents to a pri- YES Influences receptor activity on target cells
mary care clinic with a history of anxi-
ety. The advanced practice registered Correct! This medication influences the activity in
nurse reviews the mechanism of ac- the receptors, and it targets cells.
tion by which many neuropharmaco-
logical agents act and decides to pre-
scribe citalopram.
What is the mechanism of action of
this medication?
6. A patient is admitted with a diagno- NO Modulates the effects of glutamate at NMDA
sis of Huntington disease. On admis- receptors
sion, the patient exhibits uncontrolled YES Inhibits neurotransmitter GABA
twitching, difficulty walking, trouble NO Halts the breakdown of acetylcholine by
swallowing, confusion, and memory acetylcholinesterase
, 2024/25|WGU D116 Pharmacology ||2024-2025 most recent version|Co
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loss. The advanced practice registered Alters the synthesis and release of norepineph-
nurse (APRN) prescribes baclofen. rine, serotonin, and dopamine
What is the mechanism of action of Incorrect. Cholinesterase inhibitors prevent
this medication? the breakdown of acetylcholine by acetyl-
cholinesterase. They are used in patients with
Alzheimer's.
Correct! Huntington's disease involves a defi-
ciency of the neurotransmitters acetylcholine and
y-aminobutyric acid in the basal ganglia and ex-
trapyramidal system.
7. A 21-year-old patient accompanied by Atonic
a parent comes to a clinic for an emer- NO Myoclonic
gency visit with an advanced practice YES Tonic-clonic
registered nurse (APRN) following a Absence
seizure. Upon interviewing the patient Incorrect. Myoclonic seizures consist of a sudden
and the parent, the APRN determines muscle contraction that lasts for just one second.
that the seizure is classified by marked Correct! A tonic-clonic seizure is a type of seizure
impairment of consciousness and is that is also called a convulsion. This type of seizure
followed by a period of central nervous can include muscle stiffness, loss of conscious-
system (CNS) depression. ness, and body jerking.
Which type of seizure is this patient
experiencing?
8. A patient has been taking oral oxy- YES Physical dependence
codone every six hours for back pain Correct! The patient suddenly stopping the med-
during the past three years. The pa- ication will cause physical symptoms that can
tient suddenly decides to stop taking range from nausea to seizures.
the pain medication and is trying an al-
ternative therapy without a clinician's
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approval.
Which risk is of clinical concern?
9. An advanced practice registered nurse YES Bupropion
has diagnosed a 44-year-old male with
depression. A plan is developed to Correct! Bupropion does not cause sexual dys-
start treatment with medication. The function. This will help the patient with a history of
patient has a history of sexual dys- sexual dysfunction. This will enhance the patient's
function and is concerned about tak- libido, which will help with both depression and
ing medication that may worsen this sexual dysfunction.
condition.
Which antidepressant has the benefit
of enhancing libido?
10. A patient is wheezing and short of YES Tachycardia
breath. The nurse assesses a heart
rate of 88 beats per minute, a respi- Correct! Beta-agonists are used for asthma be-
ratory rate of 24 breaths per minute, cause of their beta2 effects on bronchial smooth
and a blood pressure of 124/78 mm muscle, causing dilation. Beta1 effects cause
Hg. The prescriber orders a nonspecif- tachycardia and hypertension. Beta receptors do
ic beta-agonist medication. not exert effects on the bladder.
Besides evaluating the patient for a
reduction in respiratory distress, the
nurse should monitor for which side
effect?
11. A patient is experiencing toxic side ef- YES Physostigmine
fects from atropine, including deliri-
um and hallucinations. Which medica- Correct! Physostigmine is the drug of choice for
tion should the provider administer? treating poisoning from atropine and other drugs
that cause muscarinic blockade. Donepezil is used
prehensive questions and verified answers/accurate solutions|Already
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1. A patient presents to an emer- YES With food or an empty stomach
gency room complaining of palpita-
tions and irregular heartbeat. The
advanced practice registered nurse
(APRN) places the patient on a car-
diac monitor and observes atrial fibril-
lation. The APRN orders dofetilide.
How should the APRN recommend this
medication be taken?
2. A 70-year-old male calls a clinic com- Do not take the nitroglycerin and call 911
plaining of chest pain that started after
having sexual activity. He took silde- Taking the medications together can cause a seri-
nafil 50 mg about eight hours ago. He ous drop in blood pressure leading to cardiovas-
has nitroglycerin 0.3 mg on hand. cular collapse.
How should the advanced practice reg-
istered nurse respond?
3. A patient diagnosed with bipolar disor- A baseline blood urea nitrogen (BUN) and crea-
der who is in a mental health clinic is tinine (CREA) level needs to be drawn to assess
discussing the possibility of beginning kidney function prior to treatment.
lithium with an advanced practice reg-
istered nurse (APRN). The patient ex- This drug can cause decreased renal function,
presses understanding and wishes to and a baseline should be drawn for future com-
proceed with treatment. The APRN ex- parison.
plains to the patient that this medica-
tion requires specific lab monitoring
and wants to draw baseline labs. The
patient asks why the test is needed.
, 2024/25|WGU D116 Pharmacology ||2024-2025 most recent version|Co
prehensive questions and verified answers/accurate solutions|Already
graded A+|Get it 100% correct.
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Which explanation should the APRN
provide to this patient?
4. An advanced practice registered nurse YES A 54-year-male with a medical history of hy-
(APRN) is reviewing the medications pertension, mild eczema, and previous history of
that will be commonly experienced a urolithiasis where all is well controlled and there
with a new nurse to determine are no current complications
whether the drugs are safe for the pa-
tients. The new nurse is given a sce-
nario where a patient is being pre-
scribed sildenafil 25 mg po prn, a pro-
totype drug for erectile dysfunction.
Which patient may take this drug safe-
ly?
5. A 30-year-old patient presents to a pri- YES Influences receptor activity on target cells
mary care clinic with a history of anxi-
ety. The advanced practice registered Correct! This medication influences the activity in
nurse reviews the mechanism of ac- the receptors, and it targets cells.
tion by which many neuropharmaco-
logical agents act and decides to pre-
scribe citalopram.
What is the mechanism of action of
this medication?
6. A patient is admitted with a diagno- NO Modulates the effects of glutamate at NMDA
sis of Huntington disease. On admis- receptors
sion, the patient exhibits uncontrolled YES Inhibits neurotransmitter GABA
twitching, difficulty walking, trouble NO Halts the breakdown of acetylcholine by
swallowing, confusion, and memory acetylcholinesterase
, 2024/25|WGU D116 Pharmacology ||2024-2025 most recent version|Co
prehensive questions and verified answers/accurate solutions|Already
graded A+|Get it 100% correct.
Study online at https://quizlet.com/_g5yr8e
loss. The advanced practice registered Alters the synthesis and release of norepineph-
nurse (APRN) prescribes baclofen. rine, serotonin, and dopamine
What is the mechanism of action of Incorrect. Cholinesterase inhibitors prevent
this medication? the breakdown of acetylcholine by acetyl-
cholinesterase. They are used in patients with
Alzheimer's.
Correct! Huntington's disease involves a defi-
ciency of the neurotransmitters acetylcholine and
y-aminobutyric acid in the basal ganglia and ex-
trapyramidal system.
7. A 21-year-old patient accompanied by Atonic
a parent comes to a clinic for an emer- NO Myoclonic
gency visit with an advanced practice YES Tonic-clonic
registered nurse (APRN) following a Absence
seizure. Upon interviewing the patient Incorrect. Myoclonic seizures consist of a sudden
and the parent, the APRN determines muscle contraction that lasts for just one second.
that the seizure is classified by marked Correct! A tonic-clonic seizure is a type of seizure
impairment of consciousness and is that is also called a convulsion. This type of seizure
followed by a period of central nervous can include muscle stiffness, loss of conscious-
system (CNS) depression. ness, and body jerking.
Which type of seizure is this patient
experiencing?
8. A patient has been taking oral oxy- YES Physical dependence
codone every six hours for back pain Correct! The patient suddenly stopping the med-
during the past three years. The pa- ication will cause physical symptoms that can
tient suddenly decides to stop taking range from nausea to seizures.
the pain medication and is trying an al-
ternative therapy without a clinician's
, 2024/25|WGU D116 Pharmacology ||2024-2025 most recent version|Co
prehensive questions and verified answers/accurate solutions|Already
graded A+|Get it 100% correct.
Study online at https://quizlet.com/_g5yr8e
approval.
Which risk is of clinical concern?
9. An advanced practice registered nurse YES Bupropion
has diagnosed a 44-year-old male with
depression. A plan is developed to Correct! Bupropion does not cause sexual dys-
start treatment with medication. The function. This will help the patient with a history of
patient has a history of sexual dys- sexual dysfunction. This will enhance the patient's
function and is concerned about tak- libido, which will help with both depression and
ing medication that may worsen this sexual dysfunction.
condition.
Which antidepressant has the benefit
of enhancing libido?
10. A patient is wheezing and short of YES Tachycardia
breath. The nurse assesses a heart
rate of 88 beats per minute, a respi- Correct! Beta-agonists are used for asthma be-
ratory rate of 24 breaths per minute, cause of their beta2 effects on bronchial smooth
and a blood pressure of 124/78 mm muscle, causing dilation. Beta1 effects cause
Hg. The prescriber orders a nonspecif- tachycardia and hypertension. Beta receptors do
ic beta-agonist medication. not exert effects on the bladder.
Besides evaluating the patient for a
reduction in respiratory distress, the
nurse should monitor for which side
effect?
11. A patient is experiencing toxic side ef- YES Physostigmine
fects from atropine, including deliri-
um and hallucinations. Which medica- Correct! Physostigmine is the drug of choice for
tion should the provider administer? treating poisoning from atropine and other drugs
that cause muscarinic blockade. Donepezil is used
