Cell Biology Exam 3 Question Bank
1. Imagine that you have added the ER retention (KDEL) signal to the C-terminus
of a cytoplasmic protein. If the gene was expressed in a cell, predict the final
location in which your protein will localize.
a. Mitochondria
b. ER
c. Cytoplasm
d. Nucleus
Cytoplasm
2. Which of the following protein is responsible for the ATP dependent uncoating
of the clathrin from the nascent vesicle?
a. Adaptin
b. Hsc 70
c. Rab
d. t-SNARE
Hsc 70
3. Coat proteins such as Clathrin would dissociate from the newly internalized
vesicles so that ____ .
a. the cargo proteins can associate with a receptor on the target membrane
b. the cargo proteins can dissociate with a receptor on the vesicular membrane
c. t-SNARE proteins can associate with the cargo proteins
d. Rab proteins can associate with their proper tethering proteins
Rab proteins can associate with their proper tethering proteins
4. During the process of macropinocytosis, ____.
a. significant amount of fluid will be internalized
b. a specific phospholipid will function as a receptor
c. a specific protein will function as a receptor
d. a specific protein that function as a receptor will be destructed
, significant amount of fluid will be internalized
5. Which of the following statement on SRP (Signal Recognition Particle) is NOT
true?
a. An ER signal sequence and an SRP direct a ribosome to the SRP Receptor on
the ER membrane.
b. SRP binding to the ER signal sequence on a Ribosome pauses translation
c. SRP receptor localizes on the ER membrane
d. SRP binding to the start transfer sequence will inhibit the Ribosome binding to
the ER
SRP binding to the start transfer sequence will inhibit the Ribosome binding to
the ER
6. Animal cells contain numerous membrane proteins that are decorated with
oligosaccharide. Which of the following statement is false?
a. The glycosylated membrane proteins gain the oligosaccharide in the ER.
b. The oligosaccharides decorated on the glycosylated proteins are transferred
as a preformed bloc called Dolichol.
c. When an oligosaccharide is linked to a protein through the N-Linked
glycosylation, the oligosaccharide is covalently linked to the amino terminus of
the protein.
When an oligosaccharide is linked to a protein through the N-Linked
glycosylation, the oligosaccharide is covalently linked to the amino terminus of
the protein.
7. Which of the following is a member of local mediators?
a. Delta
b. Acetylcholine
c. Nitric Oxide
d. Adrenaline
Nitric Oxide
1. Imagine that you have added the ER retention (KDEL) signal to the C-terminus
of a cytoplasmic protein. If the gene was expressed in a cell, predict the final
location in which your protein will localize.
a. Mitochondria
b. ER
c. Cytoplasm
d. Nucleus
Cytoplasm
2. Which of the following protein is responsible for the ATP dependent uncoating
of the clathrin from the nascent vesicle?
a. Adaptin
b. Hsc 70
c. Rab
d. t-SNARE
Hsc 70
3. Coat proteins such as Clathrin would dissociate from the newly internalized
vesicles so that ____ .
a. the cargo proteins can associate with a receptor on the target membrane
b. the cargo proteins can dissociate with a receptor on the vesicular membrane
c. t-SNARE proteins can associate with the cargo proteins
d. Rab proteins can associate with their proper tethering proteins
Rab proteins can associate with their proper tethering proteins
4. During the process of macropinocytosis, ____.
a. significant amount of fluid will be internalized
b. a specific phospholipid will function as a receptor
c. a specific protein will function as a receptor
d. a specific protein that function as a receptor will be destructed
, significant amount of fluid will be internalized
5. Which of the following statement on SRP (Signal Recognition Particle) is NOT
true?
a. An ER signal sequence and an SRP direct a ribosome to the SRP Receptor on
the ER membrane.
b. SRP binding to the ER signal sequence on a Ribosome pauses translation
c. SRP receptor localizes on the ER membrane
d. SRP binding to the start transfer sequence will inhibit the Ribosome binding to
the ER
SRP binding to the start transfer sequence will inhibit the Ribosome binding to
the ER
6. Animal cells contain numerous membrane proteins that are decorated with
oligosaccharide. Which of the following statement is false?
a. The glycosylated membrane proteins gain the oligosaccharide in the ER.
b. The oligosaccharides decorated on the glycosylated proteins are transferred
as a preformed bloc called Dolichol.
c. When an oligosaccharide is linked to a protein through the N-Linked
glycosylation, the oligosaccharide is covalently linked to the amino terminus of
the protein.
When an oligosaccharide is linked to a protein through the N-Linked
glycosylation, the oligosaccharide is covalently linked to the amino terminus of
the protein.
7. Which of the following is a member of local mediators?
a. Delta
b. Acetylcholine
c. Nitric Oxide
d. Adrenaline
Nitric Oxide
