NURS6203
Advanced Pharmacology
Comprehensive Midterm Review (Qns & Ans)
2025
Multiple Choice Questions
1. Which of the following pharmacokinetic changes is most likely
to occur in older adults?
- A) Increased hepatic metabolism
- B) Decreased renal excretion
- C) Enhanced gastrointestinal absorption
- D) Reduced protein binding
ANS: B) Decreased renal excretion.
©2024/2025
, Rationale: Aging is often associated with a decline in renal
function, leading to slower excretion of drugs.
2. A patient on warfarin therapy has an increased risk of bleeding.
Which of the following supplements should be avoided?
- A) Vitamin C
- B) Vitamin D
- C) Vitamin E
- D) Vitamin B12
ANS: C) Vitamin E.
Rationale: Vitamin E can potentiate the effects of warfarin,
increasing the risk of bleeding.
3. Which drug class is primarily used to treat arrhythmias through
sodium channel blockade?
- A) Beta-blockers
- B) Calcium channel blockers
- C) ACE inhibitors
- D) Class I antiarrhythmics
ANS: D) Class I antiarrhythmics.
©2024/2025
, Rationale: Class I antiarrhythmics work by blocking sodium
channels, which helps regulate heart rhythm.
4. Which of the following drugs is a monoclonal antibody used in
cancer therapy?
- A) Methotrexate
- B) Doxorubicin
- C) Trastuzumab
- D) Cisplatin
ANS: C) Trastuzumab.
Rationale: Trastuzumab is a monoclonal antibody targeting
the HER2 receptor in certain breast cancers.
5. What is the primary therapeutic use of selective serotonin
reuptake inhibitors (SSRIs)?
- A) Diabetes management
- B) Hypertension
- C) Depression treatment
- D) Antimicrobial therapy
ANS: C) Depression treatment.
©2024/2025
Advanced Pharmacology
Comprehensive Midterm Review (Qns & Ans)
2025
Multiple Choice Questions
1. Which of the following pharmacokinetic changes is most likely
to occur in older adults?
- A) Increased hepatic metabolism
- B) Decreased renal excretion
- C) Enhanced gastrointestinal absorption
- D) Reduced protein binding
ANS: B) Decreased renal excretion.
©2024/2025
, Rationale: Aging is often associated with a decline in renal
function, leading to slower excretion of drugs.
2. A patient on warfarin therapy has an increased risk of bleeding.
Which of the following supplements should be avoided?
- A) Vitamin C
- B) Vitamin D
- C) Vitamin E
- D) Vitamin B12
ANS: C) Vitamin E.
Rationale: Vitamin E can potentiate the effects of warfarin,
increasing the risk of bleeding.
3. Which drug class is primarily used to treat arrhythmias through
sodium channel blockade?
- A) Beta-blockers
- B) Calcium channel blockers
- C) ACE inhibitors
- D) Class I antiarrhythmics
ANS: D) Class I antiarrhythmics.
©2024/2025
, Rationale: Class I antiarrhythmics work by blocking sodium
channels, which helps regulate heart rhythm.
4. Which of the following drugs is a monoclonal antibody used in
cancer therapy?
- A) Methotrexate
- B) Doxorubicin
- C) Trastuzumab
- D) Cisplatin
ANS: C) Trastuzumab.
Rationale: Trastuzumab is a monoclonal antibody targeting
the HER2 receptor in certain breast cancers.
5. What is the primary therapeutic use of selective serotonin
reuptake inhibitors (SSRIs)?
- A) Diabetes management
- B) Hypertension
- C) Depression treatment
- D) Antimicrobial therapy
ANS: C) Depression treatment.
©2024/2025