Lehne's Basic
Principles Of
Pharmacotherapeut
ics for Advanced
Practice Nurses
and Physician
Assistants 2nd
Edition Revised
2024/2025
Questions and
Answers
CHAPTER I: Basic Principles of Pharmacology
,Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and
Physician
Assistants, 2nd Edition
QUESTIONS
A patient with bipolar disorder is prescribed daily lithium. Which action is most important
for the provider to take in order to determine if the therapeutic level is maintained?
✓ Order periodic laboratory testing.
Which factor best supports an increase for full prescriptive authority for both advanced
practice registered nurses (APRNs) and physician assistants (PAs)?
✓ More patients will have access to health care.
A pediatric patient prescribed ampicillin for streptococcal pharyngitis reports new onset
of a pruritic, dull red, maculopapular rash on the chest and neck. Which action is most
important for the provider to take to minimize this patient's risk for injury?
✓ Discontinue the ampicillin.
Which prescriber action will have the greatest impact on the patient's commitment to
adherence to any type of medication therapy?
✓ Providing medication education that the patient can easily understand
Which patient statement suggests to the provider that the patient's nonadherence with
their medication plan is related to dissatisfaction with the therapy?
✓ "I've been taking this medication for well over a week and I lost only a half a pound."
How can the prescriber's regular collaboration with a pharmacist improve positive
outcomes for patients?
✓ Pharmacists have additional information on drug interactions. The pharmacist can
suggest adequate medication dosing. Pharmacists have firsthand knowledge of the
facility formulary.
, Which statements made by the prescriber demonstrate an understanding of effective
medication education?
✓ "This medication needs to be stored in the refrigerator. "Take 3 tablets daily: 1 with
breakfast, 1 with lunch, and one with dinner." "You need to take the medication as
we discussed until all the tablets are gone." "Call the office immediately if you begin
experiencing any itching, headache, or difficulty breathing."
The patient who has been prescribed lithium for a diagnosis of bipolar disorder asks why
blood tests are required on a regular basis. Which provider responses demonstrate an
understanding of why the patient requires a variety of laboratory tests?
✓ "We need to monitor how your thyroid is functioning." "We need to monitor kidney
function while you are on this drug. This medication can cause you to lose sodium, so
we need to measure sodium levels."
When prescribing lovastatin, what will a provider advise to decrease the risk of
developing muscle toxicity?
✓ Substitute grapefruit juice with orange juice
When prescribing drugs with a narrow therapeutic index, what intervention does the
provider take to decrease risk to the patient?
✓ Monitor the patient's plasma drug levels at regular intervals.
A patient reports that a medication no longer effectively alleviates symptoms. What
process informs the provider's response to the patient's concerns?
✓ Desensitization of receptor sites results from continual exposure to the drug.
A patient reports that Brand X tablets work faster than Brand Y tablets of the same
amount of the same drug. Which statement informs the prescriber's response when
explaining this phenomenon to the patient?
✓ Inactive ingredients used in composition can result in differing rates of dissolution,
which can alter the drug's onset of action.
Principles Of
Pharmacotherapeut
ics for Advanced
Practice Nurses
and Physician
Assistants 2nd
Edition Revised
2024/2025
Questions and
Answers
CHAPTER I: Basic Principles of Pharmacology
,Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and
Physician
Assistants, 2nd Edition
QUESTIONS
A patient with bipolar disorder is prescribed daily lithium. Which action is most important
for the provider to take in order to determine if the therapeutic level is maintained?
✓ Order periodic laboratory testing.
Which factor best supports an increase for full prescriptive authority for both advanced
practice registered nurses (APRNs) and physician assistants (PAs)?
✓ More patients will have access to health care.
A pediatric patient prescribed ampicillin for streptococcal pharyngitis reports new onset
of a pruritic, dull red, maculopapular rash on the chest and neck. Which action is most
important for the provider to take to minimize this patient's risk for injury?
✓ Discontinue the ampicillin.
Which prescriber action will have the greatest impact on the patient's commitment to
adherence to any type of medication therapy?
✓ Providing medication education that the patient can easily understand
Which patient statement suggests to the provider that the patient's nonadherence with
their medication plan is related to dissatisfaction with the therapy?
✓ "I've been taking this medication for well over a week and I lost only a half a pound."
How can the prescriber's regular collaboration with a pharmacist improve positive
outcomes for patients?
✓ Pharmacists have additional information on drug interactions. The pharmacist can
suggest adequate medication dosing. Pharmacists have firsthand knowledge of the
facility formulary.
, Which statements made by the prescriber demonstrate an understanding of effective
medication education?
✓ "This medication needs to be stored in the refrigerator. "Take 3 tablets daily: 1 with
breakfast, 1 with lunch, and one with dinner." "You need to take the medication as
we discussed until all the tablets are gone." "Call the office immediately if you begin
experiencing any itching, headache, or difficulty breathing."
The patient who has been prescribed lithium for a diagnosis of bipolar disorder asks why
blood tests are required on a regular basis. Which provider responses demonstrate an
understanding of why the patient requires a variety of laboratory tests?
✓ "We need to monitor how your thyroid is functioning." "We need to monitor kidney
function while you are on this drug. This medication can cause you to lose sodium, so
we need to measure sodium levels."
When prescribing lovastatin, what will a provider advise to decrease the risk of
developing muscle toxicity?
✓ Substitute grapefruit juice with orange juice
When prescribing drugs with a narrow therapeutic index, what intervention does the
provider take to decrease risk to the patient?
✓ Monitor the patient's plasma drug levels at regular intervals.
A patient reports that a medication no longer effectively alleviates symptoms. What
process informs the provider's response to the patient's concerns?
✓ Desensitization of receptor sites results from continual exposure to the drug.
A patient reports that Brand X tablets work faster than Brand Y tablets of the same
amount of the same drug. Which statement informs the prescriber's response when
explaining this phenomenon to the patient?
✓ Inactive ingredients used in composition can result in differing rates of dissolution,
which can alter the drug's onset of action.
