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ONS Chemotherapy Immunotherapy Certificate New Exam 100% Verified!!

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ONS Chemotherapy Immunotherapy Certificate New Exam 100% Verified!!...

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ONS Chemotherapy Immunotherapy Certificate New
Exam 100% Verified!!


2025-2026 Newest


3 stages of cell division: - Answer >>Interphase

Mitotic phase

Cytokinesis

6 main types of immunotherapy - Answer >>1. Monoclonal antibodies

2. Immune checkpoint inhibitors

3. Cancer vaccines

4. Nonspecific immunotherapies

5. Adoptive cell therapy (CAR T-cell therapy)

6. Oncolytic virus therapy



mAbs MOA - Answer >>Mark cancer cell surface receptor/antigen to make the cell
visible to the immune system to destroy



Different types of mAbs used in treatment of cancer - Answer >>Naked mAbs

Conjugated monoclonal antibodies

Bispecific monoclonal antibodies



mAbs ending in "-ximab" source - Answer >>Chimeric human-mouse



mAbs ending in "-zumab" source - Answer >>Humanized mouse

,mAbs ending in "-umab" source - Answer >>Fully human



mAbs ending in "-omab" source - Answer >>Murine mouse



Immune checkpoint inhibitors MOA - Answer >>Prevent cancer cells from turning off T
cells --> allows T cells to infiltrate a tumor and stop it from growing



Immune checkpoint inhibitors initially cause tumors to swell, making it appear as if the
tumor is growing. This is called _____________ - Answer >>Pseudoprogression



2 main types of cancer vaccines - Answer >>Preventative/prophylactic

Treatment/therapeutic



Mechanism of action of nonspecific immunotherapies Answer >> General stimulation of
the immune system, hopefully leading to a better immune response against cancer cells



Adoptive cell therapy MOA Answer >> T cells are taken out of the patient

T cells are grown in the laboratory

*This expands amount of T cells able to kill cancer or fight infection*

T cells are returned to patient to aid the immune system



Oncolytic virus therapy MOA - Answer >>Viruses that can naturally infect or be
genetically engineered to infect and kill a cancer cell that do not harm normal cells



Common side effects of immunotherapies - Answer >>Fatigue

Diarrhea

Colitis

Musculoskeletal pain

Dermatitis

,Common treatment for immunotherapy side effects - Answer >>Corticosteroids



Results of immunotherapy agents most commonly occur between ____________ after
starting therapy - Answer >>12-16 weeks



Hierarchy of controls when controlling workplace hazards - Answer >>Elimination

Substitution

Engineering controls

Administrative controls

PPE



3 stages of interphase: - Answer >>First growth phase (G1)

Synthesis phase (S phase)

Second growth phase (G2)



4 stages of mitosis: - Answer >>Prophase

Metaphase

Anaphase

Telophase



Innate immunity: - Answer >>Nonspecific response, either:

1. Barrier

skin

mucous membranes

flora of skin/gut

2. Cellular elements

, phagocytes

natural killer cells

granulocytes

macrophages



Adaptive immunity: - Answer >>Follows if innate immunity is unsuccessful. Memory
immunity including:

1. Humoral immunity (production of antibodies or immunoglobulins)

2. Cell mediated immunity (dependent upon T cells)

3. Regulatory T -cells (prevent autoimmune reactions and limit inflammatory responses)



Define mutations - Answer >>Variations in the nucleotide sequence of a gene



3 main goals of treatment: - Answer >>Cure

Control

Palliation



Define neoadjuvant therapy - Answer >>Treatment is given prior to surgery to shrink the
tumor



Define adjuvant therapy - Answer >>Additional cancer treatment given after the primary
treatment to lower the risk that the cancer reoccur



Define conditioning/preparative therapy - Answer >>Treatments used to prepare a
patient for stem cell transplantation



2 types of conditioning therapies: - Answer >>Myeloablative

Nonmyeloablative

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