TEST BANK For Katzung's Basic and Clinical Pharmacology, 16th Edition By {Todd W. Vanderah, 2024,} Verified Chapters 1 - 66, Complete Newest Version

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY
16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-
66/COMPLETE GUIDE 2024-2025

,CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a hospital client who
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is having a computed tomography (CT) scan. The nursing attendant worki
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ng on the oncology unit administers chemotherapy to hospital clients who
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have cancer. At the Public Health Department, a nursing attendant adminis
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ters a measles-mumps-rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology best de
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scribes the actions of all three qm qm qm qm qm




nursing attendants? qm




A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ACCURATE CHOICE:- qm B
Reasoning :->>>>>> qm




Pharmacology is the study of the biologic effects of chemicals. Nursing atte qm qm qm qm qm qm qm qm qm qm qm




ndants are involved with clinical pharmacology or pharmacotherapeutics, w
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hich is a branch of pharmacology that deals with the uses of drugs to treat,pr
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event, and diagnose disease. The radiology nursing attendant is administeri
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ng a drug to help diagnose a disease. The oncology nursing attendant is ad
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ministering a drug to help treat a disease. Pharmacoeconomics includes any
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costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body and qm qm qm qm qm qm qm qm




pharmacokinetics is how the body acts on the body. qm qm qm qm qm qm qm qm




2.
When involved in phase III drug evaluation studies, w
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hatresponsibilities would the nursing attendant have?
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A) Working with animals who are given experimental drugs qm qm qm qm qm qm qm




B) Choosing appropriate hospital clients to be involved in the drug study
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C) Monitoring and observing hospital clients closely for adverse effects qm qm qm qm qm qm qm q m




D) Conducting research to determine effectiveness of the drug qm qm qm qm qm qm qm

,ACCURATE CHOICE:- qm C
Reasoning:->>>>>>

Phase III studies involve use of a drug in a vast clinical population in which
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hospital clients are asked to record any symptoms they experience while ta
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king the drugs. Nursing attendants may be responsible for helping collect a
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nd analyzethe information to be shared with the Food and Drug Administr
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ation (FDA)but would not conduct research independently because nursin
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g attendants donot prescribe medications. Use of animals in drug testing is
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done in the preclinical trials. Select hospital clients who are involved in ph
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ase II studies to participate in studies where the participants have the disea
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se the drug is intended to treat. These hospital clients are monitored closel
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y for drug action and adverse effects. Phase I studies involve healthy huma
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n volunteers who are usually paid for their participation. Nursing attendan
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ts may observe for
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adverse effects and toxicity. qm qm qm




3.
A physician has ordered intramuscular (IM) injections of morphine, a nar
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cotic, every 4 hours as needed for pain in a motor vehicle accident victim.The
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nursing attendant is aware this drug has a high abuse potential. Under wha
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t category would morphine be classified?
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A) Schedule I qm




B) Schedule II qm




C) Schedule III qm




D) Schedule IV qm




ACCURATE CHOICE:- qm B
Reasoning:->>>>>>

Narcotics with a high abuse potential are classified as Schedule II drugs bec
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ause of severe dependence liability. Schedule I drugs have high abuse poten
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tial and no accepted medical use. Schedule III drugs have a lesser abuse pot
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ential than II and an accepted medical use. Schedule IV drugs havelow abuse
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potential and limited dependence liability. qm qm qm qm




4.
What concept is considered when generic drugs are substituted for bra
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ndname drugs? q
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A) Bioavailability

, Page 5 of 822 qm qm qm




B) Critical concentration qm




C) Distribution
D) Half-life
ACCURATE CHOICE:-A qm




Reasoning:->>>>>>

Bioavailability is the portion of a dose of a drug that reaches the systemic ci qm qm qm qm qm qm qm qm qm qm qm qm qm qm




rculation and is available to act on body cells. Binders used in a generic dru
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g may not be the same as those used in the brand name drug. Therefore, th
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e way the body breaks down and uses the drug may differ, which may elimi
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nate a generic drug substitution. Critical concentration is the amount ofa dr
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ug that is needed to cause a therapeutic effect and should not differ betwee
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n generic and brand name medications. Distribution is the phase of pharma
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cokinetics, which involves the movement of a drug to the bodys tissues and
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is the same in generic and brand name drugs. A drugs half-
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life isthe time it takes for the amount of drug to decrease to half the peak le
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vel, which should not change when substituting a generic medication.
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5. A nursing attendant is assessing the hospital clients home medication use. After
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listening to the hospital client list current medications, the nursing attend
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ant askswhat priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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ACCURATE CHOICE:- qm D
Reasoning:->>>>>>

It is important for the nursing attendant to specifically question use of over
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- the-
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counter medications because hospital clients may not consider them import
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ant. The hospital client is unlikely to know the meaning of orphan drugs u
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nless they too are primary health care providers. Safety during pregnancy,
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use of a genericmedication, or classification of orphan drugs are things the
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hospital client would be unable to answer but could be found in reference b
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ooks if the nursing attendant wishes to research them.
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