STUDENT C O M P A N I O N
F U N D A M
a
E N T A L S O F
Biochemistry
LIFE AT a
THE
a MOLECULAR
LEVEL
a
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
a a a a
Donald Voet Judith G. Voet Charlotte W. Pratt
a a a a a a
,This apage ais aintentionally aleft ablank
,STUDENT COMPANION TO ACCOMPANY a a a
FUNDAMENTALS OF a
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
a a a a
Fourth Edition a
Akif Uzman
a
University of Houston a a
Jerry Johnson
a
University of Houston a a
Joseph Eichberg a
University of Houston a a
William Widger a
University of Houston a a
Donald Voet a
University of Pennsylvania a a
Judith G. Voet a a
Swarthmore College a
Charlotte W. Pratt a a
Seattle, Washington a
JOHN aWILEY a& aSONS, aINC
, Cover aDesigner aMadelyn aLesure
aCover aIllustration aNorm
aChristiansenaCover aPhotos
(Vitruvian aMan): a© aOdysseus/Alamy aand a© aDennis aHallinan/Alamy
Molecular astructures aclockwise afrom atop: abased aon aX-ray astructures athat awere arespectively
adetermined aby aRichard aDickerson aand aHorace aDrew, aCaltech; aGerard aBunick, aUniversity aof
aTennessee; aThomas aSteitz, aYale aUniversity; aAlfonso aMondragón, aNorthwestern a University; aVenki
aRamakrishnan, aMRC aLaboratory aof aMolecular aBiology, aCambridge, aU.K.; aAndrew aLeslie aand
aJohn aWalker, aMRC aLaboratoryaof aMolecular aBiology, aCambridge, aU.K.
Founded ain a1807, aJohn aWiley a& aSons, aInc. ahas abeen aa avalued asource aof aknowledge aand
aunderstanding afor amore athan a200 ayears, ahelping apeople aaround athe aworld ameet atheir aneeds aand
afulfill atheir aaspirations. aOur acompany ais abuilt aon aa afoundation aof aprinciples athat ainclude
aresponsibility ato athe acommunities awe aserve a andawhere awe alive a and awork. aIn a2008, awe alaunched a a
aCorporate aCitizenship aInitiative, aa aglobal a effort ato aaddress athe a environmental, asocial, aeconomic, aand
aethical achallenges awe aface ain aour abusiness. aAmong a the aissues a we aare aaddressing aare a carbon aimpact,
apaper aspecifications aand aprocurement, aethical aconduct awithin aour abusiness aand a among aour avendors,
aand acommunity aand acharitable asupport. aFor amore ainformation, aplease avisit aour awebsite:
awww.wiley.com/go/citizenship.
Copyright a© a2012 John aWiley a& aSons, aInc.
All arights areserved. aNo apart aof athis apublication amay abe areproduced, astored ain aa aretrieval asystem aor
atransmitted ain aany a form aor aby a any ameans, aelectronic, amechanical, aphotocopying, arecording,
ascanning aor aotherwise, aexcept aas apermitted aunder aSections a107 aor a108 aof athe a1976 aUnited aStates
aCopyright aAct, awithout aeither athe aprior awritten apermission aof athe aPublisher, aor aauthorization
athrough apayment aof athe aappropriate aper-copy afee ato athe aCopyright aClearance aCenter, aInc., a222
aRosewood aDrive, aDanvers, aMA a01923, awebsite awww.copyright.com. aRequests ato athe aPublisher afor
apermission ashould abe aaddressed ato atheaPermissions aDepartment, aJohn aWiley a& aSons, aInc. a111
aRiver aStreet, aHoboken, aNJ a07030-5774, a(201) a748-6011, afax a(201) a748-6008, awebsite
ahttp://www.wiley.com/go/permissions.
To aorder abooks aor afor acustomer aservice, aplease acall a1-800-CALL aWILEY a(225-5945).
Student aCompanion a(paperback) ISBN-13 a 978-1-1182-1827-3
Printed ain athe aUnited aStates aof
Americaa10
a a 9 a8 a7 a 6 a5 a4 a 3 a2 a1
F U N D A M
a
E N T A L S O F
Biochemistry
LIFE AT a
THE
a MOLECULAR
LEVEL
a
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
a a a a
Donald Voet Judith G. Voet Charlotte W. Pratt
a a a a a a
,This apage ais aintentionally aleft ablank
,STUDENT COMPANION TO ACCOMPANY a a a
FUNDAMENTALS OF a
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
a a a a
Fourth Edition a
Akif Uzman
a
University of Houston a a
Jerry Johnson
a
University of Houston a a
Joseph Eichberg a
University of Houston a a
William Widger a
University of Houston a a
Donald Voet a
University of Pennsylvania a a
Judith G. Voet a a
Swarthmore College a
Charlotte W. Pratt a a
Seattle, Washington a
JOHN aWILEY a& aSONS, aINC
, Cover aDesigner aMadelyn aLesure
aCover aIllustration aNorm
aChristiansenaCover aPhotos
(Vitruvian aMan): a© aOdysseus/Alamy aand a© aDennis aHallinan/Alamy
Molecular astructures aclockwise afrom atop: abased aon aX-ray astructures athat awere arespectively
adetermined aby aRichard aDickerson aand aHorace aDrew, aCaltech; aGerard aBunick, aUniversity aof
aTennessee; aThomas aSteitz, aYale aUniversity; aAlfonso aMondragón, aNorthwestern a University; aVenki
aRamakrishnan, aMRC aLaboratory aof aMolecular aBiology, aCambridge, aU.K.; aAndrew aLeslie aand
aJohn aWalker, aMRC aLaboratoryaof aMolecular aBiology, aCambridge, aU.K.
Founded ain a1807, aJohn aWiley a& aSons, aInc. ahas abeen aa avalued asource aof aknowledge aand
aunderstanding afor amore athan a200 ayears, ahelping apeople aaround athe aworld ameet atheir aneeds aand
afulfill atheir aaspirations. aOur acompany ais abuilt aon aa afoundation aof aprinciples athat ainclude
aresponsibility ato athe acommunities awe aserve a andawhere awe alive a and awork. aIn a2008, awe alaunched a a
aCorporate aCitizenship aInitiative, aa aglobal a effort ato aaddress athe a environmental, asocial, aeconomic, aand
aethical achallenges awe aface ain aour abusiness. aAmong a the aissues a we aare aaddressing aare a carbon aimpact,
apaper aspecifications aand aprocurement, aethical aconduct awithin aour abusiness aand a among aour avendors,
aand acommunity aand acharitable asupport. aFor amore ainformation, aplease avisit aour awebsite:
awww.wiley.com/go/citizenship.
Copyright a© a2012 John aWiley a& aSons, aInc.
All arights areserved. aNo apart aof athis apublication amay abe areproduced, astored ain aa aretrieval asystem aor
atransmitted ain aany a form aor aby a any ameans, aelectronic, amechanical, aphotocopying, arecording,
ascanning aor aotherwise, aexcept aas apermitted aunder aSections a107 aor a108 aof athe a1976 aUnited aStates
aCopyright aAct, awithout aeither athe aprior awritten apermission aof athe aPublisher, aor aauthorization
athrough apayment aof athe aappropriate aper-copy afee ato athe aCopyright aClearance aCenter, aInc., a222
aRosewood aDrive, aDanvers, aMA a01923, awebsite awww.copyright.com. aRequests ato athe aPublisher afor
apermission ashould abe aaddressed ato atheaPermissions aDepartment, aJohn aWiley a& aSons, aInc. a111
aRiver aStreet, aHoboken, aNJ a07030-5774, a(201) a748-6011, afax a(201) a748-6008, awebsite
ahttp://www.wiley.com/go/permissions.
To aorder abooks aor afor acustomer aservice, aplease acall a1-800-CALL aWILEY a(225-5945).
Student aCompanion a(paperback) ISBN-13 a 978-1-1182-1827-3
Printed ain athe aUnited aStates aof
Americaa10
a a 9 a8 a7 a 6 a5 a4 a 3 a2 a1
