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Summary Topic 6 Specific Defence Immunology

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Edexcel Biology Topic 6 Specific Defence Immunology Macrophages, T Helper, T Killer.

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Specific defence
Specific immune response
-

antigens

Antigen = 3D structure protein on he cell surface
S.I units membrane of cells and pathogens

↳ gene DNA bases can mutate



Specific receptors -
specific antigensa specific
pathogen .




to bind to
Lymphocytes with specific receptor a
specific
antigen
Humoral
B-cells
response : recognises specificantigen of a pathogen and
birds to it ,
fusing membranes


MHL it cell
genes process antigen and present on



surface membrane

L I- Helper all receptor binds to specific
antigen
↓ clonal expansion e
mitosis

~
some will remain in blood as
memory
cells
will secrete
cytokines by exocytosis
~
some


Ball clonal expansion stimulated
by cytokines
B cells
memory
-




B
effector alls
-




L
differentiate into plasma cells
Plasma cells produce antibodies
gene stimulated
-




>
-
DNA base transcribed
-
mRNA
> 4
polypeptides modified
- -

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