Mutation
What is Mutation : change in DNA base sequence
mutation ?
Causes alteration protein by
:
in shape
S.I units
change in DNA base sequence
-
Change in mRNA triplet code
-
change in
Sequence
-
amino acid
-
folds differently due to
different type and
position of bonds
-different shape of protein
↳
affectsfunction .
Causes
of Carcinogens
-
mutation : -
errors in DNA replication
virul
infection
-
radiation
-
ionising
Point
Types of mutation: mutation DNA base
-
>
change in a
single
Substitution -
>
swapping of base(s)
for another
Insertion -
> addition
of a base
Deletion
of base
-
> removal a
Frameshift mutation -
>
causes
remaining
amino to be
affected/changed
changes subsequent triplet
-
every
subsequent acid
changes amino
-
every
Germ cells -
>
produce gametes
Germ line to
offspring
mutation
-
>
passed
Somatic =
body cells
Somatic not to
offspring
->
mutation passed
What is Mutation : change in DNA base sequence
mutation ?
Causes alteration protein by
:
in shape
S.I units
change in DNA base sequence
-
Change in mRNA triplet code
-
change in
Sequence
-
amino acid
-
folds differently due to
different type and
position of bonds
-different shape of protein
↳
affectsfunction .
Causes
of Carcinogens
-
mutation : -
errors in DNA replication
virul
infection
-
radiation
-
ionising
Point
Types of mutation: mutation DNA base
-
>
change in a
single
Substitution -
>
swapping of base(s)
for another
Insertion -
> addition
of a base
Deletion
of base
-
> removal a
Frameshift mutation -
>
causes
remaining
amino to be
affected/changed
changes subsequent triplet
-
every
subsequent acid
changes amino
-
every
Germ cells -
>
produce gametes
Germ line to
offspring
mutation
-
>
passed
Somatic =
body cells
Somatic not to
offspring
->
mutation passed
