PAIN CONTROL WITH OPIOD ANALGESIA
NEWEST ACTUAL EXAM QUESTIONS
AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY
GRADED A+
1. What are the three receptors associated with Opiods?: mu delta kappa
2. What is the spectrum of clinical uses for opioids?: analgesics
antitussives antidiarrheal drugs
3. T/F: analgesic opioids may be classified as strong, moderate and weak
agonists and their classification is independent of potency: True
4. Opioid drugs may be classified as what three types?: agonists (full or
partial receptor)
antagonists (receptor blockers)
mixed agonist-antagonists (able to activate one opioid receptor subtype and block
another subtype)
5. What drugs are used to treat for addiction?: Antagonists: naloxone,
naltrexone, and nalmefine
6. What drugs used to treat for pain?: Strong Agonists: morphine,
methadone, meperidine, hydromorphone, fentanyl, sufentanil 7. Which drugs
, .
are strong agonists?: morphine methadone meperidine hydromorphone
fentanyl sufentanil
8. Which drugs are moderate agonists?: codeine oxycodone
9. What drugs are weak agonists?: propoxyphene
10. Which drugs are mixed agonist-antagonists?: buprenorphine
nalbuphine
11. What drugs are antagonists?: naloxone naltrexone nalmefine
12. Which drugs undergo extensive first pass metabolism?: morphine
hydromorphone oxymorphone
**but all other drugs besides these are well absorbed when taken orally**
13. Opioids are metabolized by what enzymes? and inactivate what?:
1. hepatic enzymes
2. inactivate glucuronide conjugates
14 T/F: morphine-6-glucuronide has analgesic activity equivalent to that of
morphine & morphine-3-glucuronide: True
15. T/F: The primary metabolite (morphine-3-glucuronide) is
neuroinhibitory: False: it is neuroexcitatory
NEWEST ACTUAL EXAM QUESTIONS
AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY
GRADED A+
1. What are the three receptors associated with Opiods?: mu delta kappa
2. What is the spectrum of clinical uses for opioids?: analgesics
antitussives antidiarrheal drugs
3. T/F: analgesic opioids may be classified as strong, moderate and weak
agonists and their classification is independent of potency: True
4. Opioid drugs may be classified as what three types?: agonists (full or
partial receptor)
antagonists (receptor blockers)
mixed agonist-antagonists (able to activate one opioid receptor subtype and block
another subtype)
5. What drugs are used to treat for addiction?: Antagonists: naloxone,
naltrexone, and nalmefine
6. What drugs used to treat for pain?: Strong Agonists: morphine,
methadone, meperidine, hydromorphone, fentanyl, sufentanil 7. Which drugs
, .
are strong agonists?: morphine methadone meperidine hydromorphone
fentanyl sufentanil
8. Which drugs are moderate agonists?: codeine oxycodone
9. What drugs are weak agonists?: propoxyphene
10. Which drugs are mixed agonist-antagonists?: buprenorphine
nalbuphine
11. What drugs are antagonists?: naloxone naltrexone nalmefine
12. Which drugs undergo extensive first pass metabolism?: morphine
hydromorphone oxymorphone
**but all other drugs besides these are well absorbed when taken orally**
13. Opioids are metabolized by what enzymes? and inactivate what?:
1. hepatic enzymes
2. inactivate glucuronide conjugates
14 T/F: morphine-6-glucuronide has analgesic activity equivalent to that of
morphine & morphine-3-glucuronide: True
15. T/F: The primary metabolite (morphine-3-glucuronide) is
neuroinhibitory: False: it is neuroexcitatory
