UNE biochem Unit 4 exam UPDATED
Questions with CORRECT Answers
Ubiquitination is a means of targeting a protein for which of the following cellular processes? -
CORRECT ANSWER - Proteasomal degradation
The reaction of ammonia with a-ketoglutarate is catalyzed by_______ and requires ________ as
a reactant? - CORRECT ANSWER - Glutamate dehydrogenase; NADH or NADPH
Most enzymes involved in a protein digestion require cleavage for activation. These proteins are
secreted as inactive protein forms called: - CORRECT ANSWER - Zymogens
The urea cycle takes place in which of the following sub cellular locations? - CORRECT
ANSWER - the cytosol and mitochondria
Which of the following amino acids is considered non essential because its generated by the urea
cycle? - CORRECT ANSWER - arginine
Which of the following enzymes is regulated by N-acteyl glutamate (NAGs)? - CORRECT
ANSWER - CPS I
Which of the following enzymes is correctly paired with its activator? - CORRECT
ANSWER - N-acetylglutamate synthase; arginine
Which of the following enzymes will be active in both the fed and fasted state? - CORRECT
ANSWER - Glutaminase
Which of the following compounds stimulates the synthesis of N-acetylglutamate? - CORRECT
ANSWER - arginine
, Which of the following statements is consistent with nitrogen transport in the fasted state -
CORRECT ANSWER - Glutaminase will be active
Which of the following is the primary role of glutaminase in the liver? - CORRECT
ANSWER - to free an amine group from glutamine
in the case of urea cycle deficiency, which of the following amino acids may become essential? -
CORRECT ANSWER - arginine
When is the process of autophage most likely occurring in the cell? - CORRECT
ANSWER - When there is low energy in the cell; ratio of AMP/ATP >1
Unlike many of the other metabolic pathways, the urea cycle can be active under which of the
following conditions? - CORRECT ANSWER - Both the fed and fasted state
Pepsinogen is activated by which of the following mechanisms or enzymes? - CORRECT
ANSWER - A change in pH catalyzes the activation of pepsinogen to pepsin
The process of autophagy is defined as which of the following processes? - CORRECT
ANSWER - Recycling of proteins under conditions of cellular need or starvation
Which of the following enzymes is the regulatory step in the urea cycle? - CORRECT
ANSWER - Carbamoyl phosphate synthetase (CPSI)
The pancreatic zymogen trypsinogen is activated by which of the following enzymes or
compounds? - CORRECT ANSWER - Enteropeptidase
Alanine can be shuttled from the skeletal muscle to the liver where it is deaminated by which of
the following enzymes? - CORRECT ANSWER - Alanine aminotransferase
Questions with CORRECT Answers
Ubiquitination is a means of targeting a protein for which of the following cellular processes? -
CORRECT ANSWER - Proteasomal degradation
The reaction of ammonia with a-ketoglutarate is catalyzed by_______ and requires ________ as
a reactant? - CORRECT ANSWER - Glutamate dehydrogenase; NADH or NADPH
Most enzymes involved in a protein digestion require cleavage for activation. These proteins are
secreted as inactive protein forms called: - CORRECT ANSWER - Zymogens
The urea cycle takes place in which of the following sub cellular locations? - CORRECT
ANSWER - the cytosol and mitochondria
Which of the following amino acids is considered non essential because its generated by the urea
cycle? - CORRECT ANSWER - arginine
Which of the following enzymes is regulated by N-acteyl glutamate (NAGs)? - CORRECT
ANSWER - CPS I
Which of the following enzymes is correctly paired with its activator? - CORRECT
ANSWER - N-acetylglutamate synthase; arginine
Which of the following enzymes will be active in both the fed and fasted state? - CORRECT
ANSWER - Glutaminase
Which of the following compounds stimulates the synthesis of N-acetylglutamate? - CORRECT
ANSWER - arginine
, Which of the following statements is consistent with nitrogen transport in the fasted state -
CORRECT ANSWER - Glutaminase will be active
Which of the following is the primary role of glutaminase in the liver? - CORRECT
ANSWER - to free an amine group from glutamine
in the case of urea cycle deficiency, which of the following amino acids may become essential? -
CORRECT ANSWER - arginine
When is the process of autophage most likely occurring in the cell? - CORRECT
ANSWER - When there is low energy in the cell; ratio of AMP/ATP >1
Unlike many of the other metabolic pathways, the urea cycle can be active under which of the
following conditions? - CORRECT ANSWER - Both the fed and fasted state
Pepsinogen is activated by which of the following mechanisms or enzymes? - CORRECT
ANSWER - A change in pH catalyzes the activation of pepsinogen to pepsin
The process of autophagy is defined as which of the following processes? - CORRECT
ANSWER - Recycling of proteins under conditions of cellular need or starvation
Which of the following enzymes is the regulatory step in the urea cycle? - CORRECT
ANSWER - Carbamoyl phosphate synthetase (CPSI)
The pancreatic zymogen trypsinogen is activated by which of the following enzymes or
compounds? - CORRECT ANSWER - Enteropeptidase
Alanine can be shuttled from the skeletal muscle to the liver where it is deaminated by which of
the following enzymes? - CORRECT ANSWER - Alanine aminotransferase
