UNE Biochemistry Unit 1 UPDATED
Questions with CORRECT Answers
What is primary structure of a protein? - CORRECT ANSWER - Linear sequence of
amino acids in a polypeptide chain written from the N-terminus to the C-terminus.
What kind of structure contains a-helices and B-pleated sheets? - CORRECT ANSWER -
Secondary structure
How are a-helices formed? - CORRECT ANSWER - The CARBONYL group of a peptide
bond forms a HYDROGEN bond with the AMIDE nitrogen of another peptide bond FOUR
amino acids down the chain.
Are a-helices weak and loose or compact and rigid? - CORRECT ANSWER - Compact
and rigid
a-helices comprise what fraction of secondary structures? - CORRECT ANSWER - About
1/3
Which amino acid can cause a kink in a-helices and is therefore not typically found in them? -
CORRECT ANSWER - Proline
How are B-pleated sheets formed? - CORRECT ANSWER - B strands are connected
laterally by at least two or three hydrogen backbone bonds.
B-pleated sheets are formed laterally between which groups on either B strand? - CORRECT
ANSWER - C=O groups and NH groups
In which directions do R groups on B pleated sheets always protrude? - CORRECT
ANSWER - Up or down.
, If the B-pleated sheet has a hydrophobic side, where is it? - CORRECT ANSWER -
Buried in the protein and will rarely be exposed to the polar H2O solvent.
If the B-pleated sheet has a hydrophilic side, where is it? - CORRECT ANSWER - On the
surface of the protein and exposed to the polar H2O solvent.
What are bends/turns/loops? - CORRECT ANSWER - Shorts stretches of the polypeptide
chain that are stabilized by hydrogen bonds and are NOT random
What is tertiary protein structure? - CORRECT ANSWER - The total 3D conformation of
the polypeptide chain including interactions between a-helices, B-pleated sheets and any
loops/turns/bends
The Rossman fold is an example of what type of structure? - CORRECT ANSWER -
Tertiary
What is a structural domain? - CORRECT ANSWER - A section of protein sufficient to
perform a chemical or physical task. They are DEFINED regions with CONSERVED function.
What is a motif? - CORRECT ANSWER - Common arrangement of secondary structures
to form a tertiary arrangement
What is quaternary structure? - CORRECT ANSWER - A combination of two or more
tertiary subunits that work as one functioning unit.
What are similarities between myoglobin and hemoglobin? - CORRECT ANSWER - They
are homologous. They have similar primary sequences. They both bind oxygen.
What is the function of hemoglobin? - CORRECT ANSWER - Travels through the blood
inside a red blood cell in order to deliver oxygen form the lungs to the tissues
Questions with CORRECT Answers
What is primary structure of a protein? - CORRECT ANSWER - Linear sequence of
amino acids in a polypeptide chain written from the N-terminus to the C-terminus.
What kind of structure contains a-helices and B-pleated sheets? - CORRECT ANSWER -
Secondary structure
How are a-helices formed? - CORRECT ANSWER - The CARBONYL group of a peptide
bond forms a HYDROGEN bond with the AMIDE nitrogen of another peptide bond FOUR
amino acids down the chain.
Are a-helices weak and loose or compact and rigid? - CORRECT ANSWER - Compact
and rigid
a-helices comprise what fraction of secondary structures? - CORRECT ANSWER - About
1/3
Which amino acid can cause a kink in a-helices and is therefore not typically found in them? -
CORRECT ANSWER - Proline
How are B-pleated sheets formed? - CORRECT ANSWER - B strands are connected
laterally by at least two or three hydrogen backbone bonds.
B-pleated sheets are formed laterally between which groups on either B strand? - CORRECT
ANSWER - C=O groups and NH groups
In which directions do R groups on B pleated sheets always protrude? - CORRECT
ANSWER - Up or down.
, If the B-pleated sheet has a hydrophobic side, where is it? - CORRECT ANSWER -
Buried in the protein and will rarely be exposed to the polar H2O solvent.
If the B-pleated sheet has a hydrophilic side, where is it? - CORRECT ANSWER - On the
surface of the protein and exposed to the polar H2O solvent.
What are bends/turns/loops? - CORRECT ANSWER - Shorts stretches of the polypeptide
chain that are stabilized by hydrogen bonds and are NOT random
What is tertiary protein structure? - CORRECT ANSWER - The total 3D conformation of
the polypeptide chain including interactions between a-helices, B-pleated sheets and any
loops/turns/bends
The Rossman fold is an example of what type of structure? - CORRECT ANSWER -
Tertiary
What is a structural domain? - CORRECT ANSWER - A section of protein sufficient to
perform a chemical or physical task. They are DEFINED regions with CONSERVED function.
What is a motif? - CORRECT ANSWER - Common arrangement of secondary structures
to form a tertiary arrangement
What is quaternary structure? - CORRECT ANSWER - A combination of two or more
tertiary subunits that work as one functioning unit.
What are similarities between myoglobin and hemoglobin? - CORRECT ANSWER - They
are homologous. They have similar primary sequences. They both bind oxygen.
What is the function of hemoglobin? - CORRECT ANSWER - Travels through the blood
inside a red blood cell in order to deliver oxygen form the lungs to the tissues
