Chapter 1- Basic Principles of
Pharmacology
Pharmacology -
The study of drugs and their actions on living organisms
Pharmacy -
The practice of preparing and dispensing medications
Drug -
Any substance that alters physiologic function in an organism
Understanding basic drug mechanisms -
Can help allied health professionals better understand a patient's response to a drug
It is important to understand how certain medications may affect rehabilitation procedures -
This knowledge may help optimize patient therapy
Scheduling therapy with a patient when certain drugs reach their peak effect may _____ or
______ affect the therapy session -
Improve or Negatively
Drugs that decrease pain -
(analgesics)
Drugs that improve motor skills -
(anti-Parkinson drugs)
It is important to understand possible adverse interactions
between medications and therapy treatment -
Example:
An individual taking vasodilators may experience:
Dizziness
Orthostatic Hypotension
Weakness
Pharmacotherapeutics include: -
Pharmacokinetics
Pharmacodynamics
Pharmacokinetics -
Absorption
Distribution
Metabolism
Elimination
Pharmacodynamics -
1|Page
, Systemic Effects
Cellular Effects
Pharmacotherapeutics -
The use of specific drugs to prevent, treat or diagnose a disease
________ is the clinical purpose or indication for giving a drug -
Pharmacotherapeutics
An individual with a bacterial infection may be given __________ -
an antibiotic
Pharmacokinetics -
The study of drug movement throughout the body
(How the body deals with drugs)
Pharmacokinetics Involves analysis of how a drug is: -
Absorbed
Distributed
Metabolized
Eliminated
Absorption -
Process by which drug molecules cross biological membranes
Example:
Movement of a drug from site of administration into the bloodstream
Distribution -
Movement of drug molecules through the body to peripheral tissues
Metabolism (Biotransformation) -
The process by which a drug is converted into another substance (metabolite) so
that it is no longer active
Elimination (Excretion) -
The removal of the drug or the metabolite from the body
Pharmacodynamics -
The study of the:
-Biochemical and physiologic effects of a drug
>>>>This includes systemic effects and cellular effects
-Mechanism by which a drug exerts its effect
(So, basically it is the study of what drugs do to
the body and how they do it)
_______ Relates to the body's effect on a drug -
Pharmacokinetics
________ Relates to the drug's effects on the body -
Pharmacodynamics
2|Page
Pharmacology
Pharmacology -
The study of drugs and their actions on living organisms
Pharmacy -
The practice of preparing and dispensing medications
Drug -
Any substance that alters physiologic function in an organism
Understanding basic drug mechanisms -
Can help allied health professionals better understand a patient's response to a drug
It is important to understand how certain medications may affect rehabilitation procedures -
This knowledge may help optimize patient therapy
Scheduling therapy with a patient when certain drugs reach their peak effect may _____ or
______ affect the therapy session -
Improve or Negatively
Drugs that decrease pain -
(analgesics)
Drugs that improve motor skills -
(anti-Parkinson drugs)
It is important to understand possible adverse interactions
between medications and therapy treatment -
Example:
An individual taking vasodilators may experience:
Dizziness
Orthostatic Hypotension
Weakness
Pharmacotherapeutics include: -
Pharmacokinetics
Pharmacodynamics
Pharmacokinetics -
Absorption
Distribution
Metabolism
Elimination
Pharmacodynamics -
1|Page
, Systemic Effects
Cellular Effects
Pharmacotherapeutics -
The use of specific drugs to prevent, treat or diagnose a disease
________ is the clinical purpose or indication for giving a drug -
Pharmacotherapeutics
An individual with a bacterial infection may be given __________ -
an antibiotic
Pharmacokinetics -
The study of drug movement throughout the body
(How the body deals with drugs)
Pharmacokinetics Involves analysis of how a drug is: -
Absorbed
Distributed
Metabolized
Eliminated
Absorption -
Process by which drug molecules cross biological membranes
Example:
Movement of a drug from site of administration into the bloodstream
Distribution -
Movement of drug molecules through the body to peripheral tissues
Metabolism (Biotransformation) -
The process by which a drug is converted into another substance (metabolite) so
that it is no longer active
Elimination (Excretion) -
The removal of the drug or the metabolite from the body
Pharmacodynamics -
The study of the:
-Biochemical and physiologic effects of a drug
>>>>This includes systemic effects and cellular effects
-Mechanism by which a drug exerts its effect
(So, basically it is the study of what drugs do to
the body and how they do it)
_______ Relates to the body's effect on a drug -
Pharmacokinetics
________ Relates to the drug's effects on the body -
Pharmacodynamics
2|Page
