NUR 3197 (UF-AGPCNP) Genetics & Genomics in HC Midterms (Qns & Ans) 2025.

NUR 3197

Genetics & Genomics in Health Care

Midterms (Qns & Ans)

2025




1. Which of the following technologies is most commonly used
for genome-wide association studies (GWAS)?


A) Sanger Sequencing
B) Polymerase Chain Reaction (PCR)
C) DNA Microarrays
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, D) CRISPR-Cas9


ANS: C) DNA Microarrays
Rationale: DNA microarrays are used to detect expression of
thousands of genes at once, aiding in GWAS to find genetic
variants in different populations.


2. Which ethical principle is particularly concerned with
balancing the benefits and risks of genetic testing in healthcare?


A) Autonomy
B) Beneficence
C) Justice
D) Non-maleficence


ANS: B) Beneficence
Rationale: Beneficence involves taking actions that serve the
best interests of patients, which includes weighing benefits and
risks in genetic testing.


3. What is the primary goal of pharmacogenomics?


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, A) To develop new drugs
B) To identify genetic disorders
C) To personalize drug therapy based on genetic profile
D) To provide genetic counseling


ANS: C) To personalize drug therapy based on genetic profile
Rationale: Pharmacogenomics uses genetic information to
optimize drug therapy and dosing for individuals.


4. Which of the following best describes the term "epigenome"?


A) The sequence of genes in the human genome
B) A record of chemical changes to DNA that affect gene
expression
C) A type of cancer genome
D) A subset of hereditary mutations


ANS: B) A record of chemical changes to DNA that affect
gene expression
Rationale: The epigenome consists of chemical modifications
to DNA that influence gene activity without altering the DNA
sequence.
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