PHCH 667 final Exam prep - Questions with 100%
Correct Answers | Verified |
Which of the following is not increased during hepatitis infection? - ✔✔Serum
albumin
Unconjugated bilirubin (indirect) is insoluble in aqueous conditions and cannot be
directly detected by the van der Bergh reaction. Conjugated bilirubin is formed in the
liver by UGT1A1-catalyzed glucuronidation and can be detected by the van der Bergh
reaction. - ✔✔True
In order for someone to be infected with hepatitis D, they must also be infected with
which of the following? - ✔✔Hepatitis B
Elevated ALP and normal 5-NT (or normal ALT) means the problem is probably a
nonhepatic etiology - ✔✔True
Which of the following proteins has a half-life of approximately 20 days and decreased
concentrations in serum are indicative of liver disease? - ✔✔Albumin
A new cardiovascular prevention guideline was released in 2013 by AHA and American
College of Cardiology to calculate the ASCVD risks based on risk factors. Serum
cholesterol levels (TC and HDL) are considered as risk factors in the new calculation -
✔✔True
Serum total cholesterol can be measured using chemical or enzymatic assays. Which of
the following is false about TC assays? - ✔✔In enzymatic assay, cholesterol is
quantified by LC/MS-based analytical assays.
,Which of the following is FALSE about lipoproteins? - ✔✔HDL contains the highest
percent of cholesterol in its lipid payload and is the major carrier of cholesterol in the
blood
LDL is often calculated based on the Friedewald equation. Which of the following is the
correct Friedewald equation - ✔✔[LCL-C] = [TC] - [HDL-C] - [TG]/5
If lipid profile is measured using nonfasting blood samples, which lipid results can still be
accurate? - ✔✔TC and HDL
According to the NCEP 2001 guideline, what is the desirable TC level and what HDL level
is considered low (if desirable)? - ✔✔TC < 200mg/dL and HDL < 40 mg/dL
A new cardiovascular prevention guideline was released in 2013 by AHA and American
College of Cardiology to calculate the ASCVD risks based on risk factors. Serum
cholesterol levels (Tc and HDL) are considered as risk factors in the new calculation. -
✔✔True
Triglycerides are esterified form of glycerol and fatty acids. Serum TG levels are not
significantly altered after a fatty meal. - ✔✔False
Generally, BNP and NT-BMP levels are predicative as follows: - ✔✔Low levels of BNP
or NT-BNP (100 and 300) are indicative that heart failure is unlikely
Serum biomarkers for heart attack are released into serum in which order (from first to
last)? - ✔✔Myoglobin, troponins = creatine kinase, lactase dehydrogenase
Myocardial infarction leads to death of heart muscle due to lack of oxygen which leads
to release of cardiac enzymes and proteins into the serum. Which parameters is the
, MOST challenging in terms evaluating serum biomarker results? - ✔✔Determining
when a heart attack started (time zero)
Generally, high levels of hs-CRP are predictive of which of the following? - ✔✔Lower
survival rates and recurrent events
Which of the following is true? - ✔✔UA/NSTEMI is defined by ST- depression or
prominent T-inversion and/or positive biomarkers
Which of the following characteristics is not a key role for myoglobin as an early
biomarker for MI? - ✔✔Specific isoform of protein in cardiac cells
Which of the following troponins have unique form(s) in cardiac cells and are thus used
as serum biomarkers - ✔✔Troponins I and T
What is the function of thyroid hormone? - ✔✔Regulate carbohydrate, lipid and
protein metabolism within cells
What is the most common type of laboratory assay that is widely used to assess thyroid
hormone concentrations, such as FT4? - ✔✔Immunoassay
Hypothyroidism is diagnosed by which of the following? - ✔✔Decreased T4 and
decreased T3
TSH is secreted by the _______ - ✔✔Pituitary gland
A disorder of the thyroid caused by autoimmune reaction to TSH receptor is ______ -
✔✔Grave's disease
Correct Answers | Verified |
Which of the following is not increased during hepatitis infection? - ✔✔Serum
albumin
Unconjugated bilirubin (indirect) is insoluble in aqueous conditions and cannot be
directly detected by the van der Bergh reaction. Conjugated bilirubin is formed in the
liver by UGT1A1-catalyzed glucuronidation and can be detected by the van der Bergh
reaction. - ✔✔True
In order for someone to be infected with hepatitis D, they must also be infected with
which of the following? - ✔✔Hepatitis B
Elevated ALP and normal 5-NT (or normal ALT) means the problem is probably a
nonhepatic etiology - ✔✔True
Which of the following proteins has a half-life of approximately 20 days and decreased
concentrations in serum are indicative of liver disease? - ✔✔Albumin
A new cardiovascular prevention guideline was released in 2013 by AHA and American
College of Cardiology to calculate the ASCVD risks based on risk factors. Serum
cholesterol levels (TC and HDL) are considered as risk factors in the new calculation -
✔✔True
Serum total cholesterol can be measured using chemical or enzymatic assays. Which of
the following is false about TC assays? - ✔✔In enzymatic assay, cholesterol is
quantified by LC/MS-based analytical assays.
,Which of the following is FALSE about lipoproteins? - ✔✔HDL contains the highest
percent of cholesterol in its lipid payload and is the major carrier of cholesterol in the
blood
LDL is often calculated based on the Friedewald equation. Which of the following is the
correct Friedewald equation - ✔✔[LCL-C] = [TC] - [HDL-C] - [TG]/5
If lipid profile is measured using nonfasting blood samples, which lipid results can still be
accurate? - ✔✔TC and HDL
According to the NCEP 2001 guideline, what is the desirable TC level and what HDL level
is considered low (if desirable)? - ✔✔TC < 200mg/dL and HDL < 40 mg/dL
A new cardiovascular prevention guideline was released in 2013 by AHA and American
College of Cardiology to calculate the ASCVD risks based on risk factors. Serum
cholesterol levels (Tc and HDL) are considered as risk factors in the new calculation. -
✔✔True
Triglycerides are esterified form of glycerol and fatty acids. Serum TG levels are not
significantly altered after a fatty meal. - ✔✔False
Generally, BNP and NT-BMP levels are predicative as follows: - ✔✔Low levels of BNP
or NT-BNP (100 and 300) are indicative that heart failure is unlikely
Serum biomarkers for heart attack are released into serum in which order (from first to
last)? - ✔✔Myoglobin, troponins = creatine kinase, lactase dehydrogenase
Myocardial infarction leads to death of heart muscle due to lack of oxygen which leads
to release of cardiac enzymes and proteins into the serum. Which parameters is the
, MOST challenging in terms evaluating serum biomarker results? - ✔✔Determining
when a heart attack started (time zero)
Generally, high levels of hs-CRP are predictive of which of the following? - ✔✔Lower
survival rates and recurrent events
Which of the following is true? - ✔✔UA/NSTEMI is defined by ST- depression or
prominent T-inversion and/or positive biomarkers
Which of the following characteristics is not a key role for myoglobin as an early
biomarker for MI? - ✔✔Specific isoform of protein in cardiac cells
Which of the following troponins have unique form(s) in cardiac cells and are thus used
as serum biomarkers - ✔✔Troponins I and T
What is the function of thyroid hormone? - ✔✔Regulate carbohydrate, lipid and
protein metabolism within cells
What is the most common type of laboratory assay that is widely used to assess thyroid
hormone concentrations, such as FT4? - ✔✔Immunoassay
Hypothyroidism is diagnosed by which of the following? - ✔✔Decreased T4 and
decreased T3
TSH is secreted by the _______ - ✔✔Pituitary gland
A disorder of the thyroid caused by autoimmune reaction to TSH receptor is ______ -
✔✔Grave's disease
