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COMLEX LEVEL 2 Complete (Original) Exam Study Guide

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COMLEX LEVEL 2 Complete (Original) Exam Study Guide First line treatment for Impetigo Leukocytosis w/ left shift indicates? - AnswerDicloxacillin Followed by Vanc if Beta-lactamase resistant - Excess neutrophils ... essential a bacterial infection Treatment: Hot tub folliculitis Impetigo by strep Contact dermatitis impetigo, abscess and folliculitis by staph - AnswerFluoroquinolon, Ciprofloxacin Cephalexin Topical steroid TMP-SMX © EVERLY 2025 ALL RIGHTS RESERVED. 2 | P a g e Difference between HIB and Influenzae What's the pnuemococcal vaccine for? - AnswerHIB - Cause lower respiratory infection - HIB vaccine reduce incidence since 1990s Influenzae - high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired. - Yearly vaccine - Treat w/ neuraminidase inhibitors (oseltamivir and zanamivir) and M2 protein inhibitors (adamantane derivatives). Pneumoccocal vaccine - Protects against S. Pneumoniae Media 1) Chocolate agar 2) Thayer-Martin 3) Eaton agar 4) Charcoal yeast - Answer1) H. Influenzae 2) N. Gonorrhea 3) Mycoplasma 4) Legionella Stains 1) PAS 2) India ink 3) Silver Stain - Answer1) Whipple diseae 2) C. neoformans © EVERLY 2025 ALL RIGHTS RESERVED. 3 | P a g e 3) Fungi (e.g., Pneumocystis), Legionella, Helicobacter pylori ___ antibiotics have better coverage than any other class List them - AnswerBeta-Lactam Penicillin, Cephalosporins, carbapenems, aztreonam Which bacteria are covered by Amoxicillin - AnswerHELPS H -- H. influenzae E -- E. Coli L -- Listeria P -- Proteus S -- Salmonella Piperacillin, ticarcillin, azlocillin, mezlocillin Cover what kind of bacteria What are they useful for - AnswerGram (-) • Cholecystitis and ascending cholangitis • Pyelonephritis • Bacteremia -All stuff that can climb up a tract • Hospital-acquired and ventilator-associated pneumonia • Neutropenia and fever Ceftriaxone, Cefotaxime, Ceftazidime - What class are these? © EVERLY 2025 ALL RIGHTS RESERVED. 4 | P a g e What is ceftriaxonde first line for? Avoid ceftriaxone in ____ pt. Why? - Answer3rd gen cephalosporin - Meningitis - Community-acquired pneumonia (in combination with macrolides) - Gonorrhea - Lyme involving the heart or brain Avoid ceftriaxone in neonates because of impaired biliary metabolism. Best therapy for community-acquired pneumonia, including penicillinresistant pneumococcus Use ___ for cystitis and pyelonephritis. ____ can be used as a single agent for diverticulitis and does not need metronidazole. - AnswerFluoroquinolones (Ciprofloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin) * Macrolides and doxycycline also used Ciprofloxacin Moxifloxacin Side effect of quinolones - AnswerBone growth abnormalities in children and pregnant woman Tendonitis and tendon rupture Treatment for cystitis and pneumocystis treatment/prophylaxis Side effects? - AnswerTrimethoprim/Sulfamethoxazole

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© EVERLY 2025 ALL RIGHTS RESERVED.




COMLEX LEVEL 2 Complete (Original)
Exam Study Guide


First line treatment for Impetigo


Leukocytosis w/ left shift indicates? - Answer✔Dicloxacillin


Followed by Vanc if Beta-lactamase resistant


- Excess neutrophils ... essential a bacterial infection
Treatment:


Hot tub folliculitis


Impetigo by strep


Contact dermatitis


impetigo, abscess and folliculitis by staph - Answer✔Fluoroquinolon, Ciprofloxacin


Cephalexin


Topical steroid


TMP-SMX


1|Page

, © EVERLY 2025 ALL RIGHTS RESERVED.

Difference between HIB and Influenzae


What's the pnuemococcal vaccine for? - Answer✔HIB
- Cause lower respiratory infection
- HIB vaccine reduce incidence since 1990s


Influenzae
- high fever, runny nose, sore throat, muscle pains, headache, coughing, and feeling tired.
- Yearly vaccine
- Treat w/ neuraminidase inhibitors (oseltamivir and zanamivir) and M2 protein inhibitors
(adamantane derivatives).




Pneumoccocal vaccine
- Protects against S. Pneumoniae
Media


1) Chocolate agar
2) Thayer-Martin
3) Eaton agar
4) Charcoal yeast - Answer✔1) H. Influenzae
2) N. Gonorrhea
3) Mycoplasma
4) Legionella
Stains


1) PAS
2) India ink
3) Silver Stain - Answer✔1) Whipple diseae
2) C. neoformans

2|Page

, © EVERLY 2025 ALL RIGHTS RESERVED.

3) Fungi (e.g., Pneumocystis), Legionella,
Helicobacter pylori
___ antibiotics have better coverage than any other class


List them - Answer✔Beta-Lactam


Penicillin, Cephalosporins, carbapenems, aztreonam
Which bacteria are covered by Amoxicillin - Answer✔HELPS


H --> H. influenzae
E --> E. Coli
L --> Listeria
P --> Proteus
S --> Salmonella
Piperacillin, ticarcillin, azlocillin, mezlocillin


Cover what kind of bacteria


What are they useful for - Answer✔Gram (-)


• Cholecystitis and ascending cholangitis
• Pyelonephritis
• Bacteremia
-All stuff that can climb up a tract


• Hospital-acquired and ventilator-associated pneumonia
• Neutropenia and fever
Ceftriaxone, Cefotaxime, Ceftazidime
- What class are these?


3|Page

, © EVERLY 2025 ALL RIGHTS RESERVED.


What is ceftriaxonde first line for?


Avoid ceftriaxone in ____ pt. Why? - Answer✔3rd gen cephalosporin


- Meningitis
- Community-acquired pneumonia (in combination with macrolides)
- Gonorrhea
- Lyme involving the heart or brain


Avoid ceftriaxone in neonates because of impaired biliary metabolism.
Best therapy for community-acquired pneumonia, including penicillinresistant pneumococcus


Use ___ for cystitis and pyelonephritis.


____ can be used as a single
agent for diverticulitis and does not need metronidazole. - Answer✔Fluoroquinolones
(Ciprofloxacin, Gemifloxacin, Levofloxacin, Moxifloxacin)
* Macrolides and doxycycline also used


Ciprofloxacin


Moxifloxacin
Side effect of quinolones - Answer✔Bone growth abnormalities in children and pregnant woman


Tendonitis and tendon rupture
Treatment for cystitis and pneumocystis treatment/prophylaxis


Side effects? - Answer✔Trimethoprim/Sulfamethoxazole


4|Page

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