EXAM 98 NEWEST QUESTIONS AND
CORRECT VERIFIED ANSWERS WITH
RATIONALES| PN FUNDAMENTALS ATI
PROCTORED EXAM 2024| WELL GRADE
A+|| LATEST UPDADE
P-glycoprotein - CORRECT ANSWERS-a transporter protein that moves drugs out of
cells and into the gut, urine, or bile
Parent drug - CORRECT ANSWERS-the chemical form of a drug that is administered
before it is metabolized by the body into its active or inactive metabolites
Peak effect - CORRECT ANSWERS-the time required for a drug to reach its maximum
therapeutic response in the body
Peak level - CORRECT ANSWERS-The maximum concentration of a drug in the body
after administration, usually measured in a blood sample for therapeutic drug
monitoring.
Pharmaceutics - CORRECT ANSWERS-The science of preparing and dispensing
drugs, including dosage form design.
Pharmacodynamics - CORRECT ANSWERS-the study of the effects of medications on
the body
Pharmaeconomics - CORRECT ANSWERS-The study of economic factors impacting
the cost of drug therapy.
Pharmacogenomics - CORRECT ANSWERS-The study of the influence of genetic
factors on drug response that result in the absence, overabundance, or insufficiency of
drug-metabolizing enzymes
Pharmacognosy - CORRECT ANSWERS-The study of drugs that are obtained from
natural plant and animal sources.
Pharmacokinetics - CORRECT ANSWERS-The process by which drugs are absorbed,
distributed within the body, metabolized, and excreted.
, Pharmacology - CORRECT ANSWERS-study of drugs
Pharmacotherapeutics - CORRECT ANSWERS-The treatment of pathologic conditions
through the use of drugs
Prodrug - CORRECT ANSWERS-An inactive drug dosage form that is converted to an
active metabolite by various biochemical reactions once it is inside the body.
Prototypical drug - CORRECT ANSWERS-The first form of a drug, or first in a class of
drugs
Receptor - CORRECT ANSWERS-A molecular structure within or on the outer surface
of a cell. Receptors bind specific substances (e.g., drug molecules), and one or more
corresponding cellular effects (drug actions) occur as a result of this drug-receptor
interaction.
Steady state - CORRECT ANSWERS-The physiologic state in which the amount of
drug removed via elimination is equal to the amount of drug absorbed with each dose.
Substrates - CORRECT ANSWERS-substances on which an enzyme acts
synergistic effect - CORRECT ANSWERS-Drug interactions in which the effect of a
combination of two or more drugs with similar actions is greater than the sum of the
individual effects of the same drugs given alone
Therapeutic drug monitoring - CORRECT ANSWERS-The process of measuring drug
levels to identify a patient's drug exposure and to allow adjustment of dosages with the
goals of maximizing therapeutic effects and minimizing toxicity.
Therapeutic effect - CORRECT ANSWERS-The desired or intended effect of a
particular medication.
Therapeutic index - CORRECT ANSWERS-the ratio between the toxic and therapeutic
concentrations of a drug
Tolerance - CORRECT ANSWERS-reduced response to a drug after prolonged use
Toxic - CORRECT ANSWERS-The quality of being poisonous
Toxicity - CORRECT ANSWERS-The condition of producing adverse bodily effects due
to poisonous qualities.
Toxicology - CORRECT ANSWERS-The study of poisons, including toxic drug effects,
and applicable treatments.