Organic Chemistry 2 Exam 2 Reactions-
questions with answers
Chlorination: What adds a chlorine to a benzene - **🔰 VERIFIED ANSWERS🔰
✔✔Cl2/FeCl3
Bromination: What adds a bromine to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔Br2/FeBr3
Iodination: What adds an Iodine to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔I2/CuCl2
Nitration: What adds a NO2 to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔HNO3/H2SO4
Sulfonation: What adds a SO3H - **🔰 VERIFIED ANSWERS🔰 ✔✔SO3/H2SO4
Freudal Craft Alkylation: What will add an alkyl group - **🔰 VERIFIED ANSWERS🔰
✔✔R-Cl/AlCl3
Freudal Craft Acylation: What will add an acyl group - **🔰 VERIFIED ANSWERS🔰
✔✔Acyl group/AlCl3
What are the 4 rules for freudal craft alkylation/ acylation. - **🔰 VERIFIED ANSWERS🔰
✔✔1. if there is a meta director(strong EWG) on the ring, there is no reaction
2. If there is a nitrogen w/pair NH2 on the benzylic carbon,then no reaction
3. if there is a vincylic halide or aryl halide then no reaction
4. we cannot alkylate with a straight chain alkyl group of 3 carbons or more.
, What are the 4 rules for freudal craft alkylation/ acylation. - **🔰 VERIFIED ANSWERS🔰
✔✔1. if there is a strong EWG on the ring, there is no reaction
2. If there is a nitrogen w/pair NH2 on the benzylic carbon,then no reaction
3. if there is a vincylic halide or aryl halide then no reaction
4. we cannot alkylate with a straight chain alkyl group of 3 carbons or more.
Nucleophillic substitution: What will substitute to add NH2( also a reducing group) - **🔰
VERIFIED ANSWERS🔰 ✔✔NaNH2
Reactions at Alkyl Groups on Benzene: What will add a COOH to the benzylic position
provided there is a hydrogen( there are 3) OXIDATION - **🔰 VERIFIED ANSWERS🔰
✔✔KMnO4/H2O*
O2/Co(III)
K2Cr2O7/H2SO4
Jones Reagent CrO3,H2O/H2SO4
What will brominate an allylic carbon? - **🔰 VERIFIED ANSWERS🔰 ✔✔NBS/peroxide
Reduction: What will reduce a whole benzene ring? - **🔰 VERIFIED ANSWERS🔰
✔✔H2, pt 2000 psi
or H2 Rh/C, 25
Reduction: What reagents(2) can reduce a ketone or no2 - **🔰 VERIFIED ANSWERS🔰
✔✔h2, pd/c
Sn/HCl
What do you need to do to make an NH2 - **🔰 VERIFIED ANSWERS🔰 ✔✔First add
HNO3/H2SO4
questions with answers
Chlorination: What adds a chlorine to a benzene - **🔰 VERIFIED ANSWERS🔰
✔✔Cl2/FeCl3
Bromination: What adds a bromine to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔Br2/FeBr3
Iodination: What adds an Iodine to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔I2/CuCl2
Nitration: What adds a NO2 to a benzene ring - **🔰 VERIFIED ANSWERS🔰
✔✔HNO3/H2SO4
Sulfonation: What adds a SO3H - **🔰 VERIFIED ANSWERS🔰 ✔✔SO3/H2SO4
Freudal Craft Alkylation: What will add an alkyl group - **🔰 VERIFIED ANSWERS🔰
✔✔R-Cl/AlCl3
Freudal Craft Acylation: What will add an acyl group - **🔰 VERIFIED ANSWERS🔰
✔✔Acyl group/AlCl3
What are the 4 rules for freudal craft alkylation/ acylation. - **🔰 VERIFIED ANSWERS🔰
✔✔1. if there is a meta director(strong EWG) on the ring, there is no reaction
2. If there is a nitrogen w/pair NH2 on the benzylic carbon,then no reaction
3. if there is a vincylic halide or aryl halide then no reaction
4. we cannot alkylate with a straight chain alkyl group of 3 carbons or more.
, What are the 4 rules for freudal craft alkylation/ acylation. - **🔰 VERIFIED ANSWERS🔰
✔✔1. if there is a strong EWG on the ring, there is no reaction
2. If there is a nitrogen w/pair NH2 on the benzylic carbon,then no reaction
3. if there is a vincylic halide or aryl halide then no reaction
4. we cannot alkylate with a straight chain alkyl group of 3 carbons or more.
Nucleophillic substitution: What will substitute to add NH2( also a reducing group) - **🔰
VERIFIED ANSWERS🔰 ✔✔NaNH2
Reactions at Alkyl Groups on Benzene: What will add a COOH to the benzylic position
provided there is a hydrogen( there are 3) OXIDATION - **🔰 VERIFIED ANSWERS🔰
✔✔KMnO4/H2O*
O2/Co(III)
K2Cr2O7/H2SO4
Jones Reagent CrO3,H2O/H2SO4
What will brominate an allylic carbon? - **🔰 VERIFIED ANSWERS🔰 ✔✔NBS/peroxide
Reduction: What will reduce a whole benzene ring? - **🔰 VERIFIED ANSWERS🔰
✔✔H2, pt 2000 psi
or H2 Rh/C, 25
Reduction: What reagents(2) can reduce a ketone or no2 - **🔰 VERIFIED ANSWERS🔰
✔✔h2, pd/c
Sn/HCl
What do you need to do to make an NH2 - **🔰 VERIFIED ANSWERS🔰 ✔✔First add
HNO3/H2SO4
