©FYNDLAY.
ASCP 6500 Review Exam Study Guide.
Soluable Antigen + Specific Antibody= what reaction - Answers✔Precipitation
Bone marrow stain - Answers✔Romansky and Prussian Blue
Rise in titers - Answers✔Significant in serological testing
Secondary Response - Answers✔IgG
Most common coag inhibitor - Answers✔Lupus inhibitor
3' end - Answers✔OH
Haptens are only antigenic when coupled with - Answers✔Proteins
5' end - Answers✔Phosphate
RA - Answers✔IgE
Most pathogens enter through - Answers✔Mucous membranes
Increased Megakaryocytes in bone marrow decreased platelets - Answers✔Folic Acid Def
Autoimmune disease mechanism - Answers✔Circulating immune complexes
Cells Positive acid phosphatase, not inhibited with tartate - Answers✔Hairy Cell Leukemia
Most common SLE - Answers✔nuclear antigen
Light Chains - Answers✔Kappa/Lamda
Mononucleosis - Answers✔False positive RPR
Negative Glucose oxidase and positive reducing sugars - Answers✔Non-glucose reducing sugars
such as galactose
Hep B vaccine - Answers✔Passive Immunity
Titer - Answers✔Recipricol of maximum reactive dilution
Decreased complement - Answers✔In lupus
Clinical signs of HIV but AB test are negative - Answers✔Window phase before AB production
1
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Lymphokine - Answers✔Soluable mediator produced by lymphocytes
Increased protein in urine - Answers✔renal disease
Bethseda Assay - Answers✔Used to quantify coagulation inhibitor
Platelet neutralization - Answers✔Used to see if a patient has a lupus anticoagulant.
ITP - Answers✔Ages 2-4
Spherocytes - Answers✔Membrane defect, Increased destruction of RBCs, caused by
intracorpuscular abnormality
Ependymal clump - Answers✔
MCH range - Answers✔27-33
MCHC - Answers✔33-36%
Manual Platelet count Microscope - Answers✔Phase contrase
A.A decreased in patients with sickle cell - Answers✔L-glutamine
Chediak Higashi Syndrome - Answers✔Albino, Photophobia, pyonic infections, giant dark
granules in neutrophils and monocytes
Aspirin - Answers✔Not likely to cause an abnormal thrombin time
RBCs are usually smaller - Answers✔than the nucleus of a lymphocyte
-a/aa - Answers✔silent carrier
CD20 - Answers✔B cell marker
Platelets - Answers✔do not circulate in inactive form, Spiny sticky form become activated in
response to blood vessel damage
Hemoglobin Chromosome 16 - Answers✔Alpha zeta
Hemoglobin Chromosome 11 - Answers✔beta, delta, episilon and gamma
Megaloblastic anemia - Answers✔Oval microcytes and Hypersegmented neutrophils
Doesn't soley develop in the bone marrow - Answers✔Lymphocytes
Transferrin Saturation - Answers✔(serum Iron/TIBC)X100
Beta Thalasemia minor - Answers✔B+/B, B0/B
Howell-Jolly bodies are composed of - Answers✔DNA
2
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CLL CD - Answers✔CD19, CD20, CD23, co-expression of CD5
ADAMTS13 enzyme - Answers✔Cleaving ultalarge molecules of von willebrand factor to keep
them out of circulation
Least likely to stimulate production of reactive lymphocytes - Answers✔HIV
Why ferritin is less than optimal for HH - Answers✔It is an acute phase reactant that is elevated
in a variety of clinical conditions
Barr Bodies - Answers✔Normal in Females not in males
Hexose monophosphate shunt - Answers✔Provide Reduced glutathione to prevent oxidation of
hemoglobin
CML Vs Leukmoid Reaction - Answers✔LAP stain
Aquired Hemophilia A - Answers✔Anti-Factor VIII inhibitor
HbS Protection against Sickling - Answers✔HbF
Absolute Cell count - Answers✔Total count X % of cells counted
Early abnormality in lymph node of AIDS patient - Answers✔Reactive Lymphadenopathy
Clinical symptom thrombocytopenia - Answers✔Petechiae
Lymphocyte - Answers✔Pale-Blue Cytoplasm, Nucleus oval or round
Monocyte - Answers✔Blue-Gray opaque cytoplasm, Nucleus convolutions
Newborns will develop 30% of what HB in HbH - Answers✔Bart
Abnormal Granulation - Answers✔Alder anomaly & Chediak-Higashi
Hemoglobinopathies can not be caused by - Answers✔The deletion of a global chain
Hemolytic anemia - Answers✔Not where basophilic stippling is found
Alpha Thalassemia - Answers✔Decrease in the rate of production of Alpha chains due to partial
or total deletion of the genetic code
Which is NOT associated with Macrocytosis - Answers✔Thalassemia
Warfarin inhibits vitamin K dependent factors - Answers✔2,7,9,10
Flow cytometry is NOT a useful tool in - Answers✔Hepatitis
Clot would have most of an effect on - Answers✔Platelets
3
ASCP 6500 Review Exam Study Guide.
Soluable Antigen + Specific Antibody= what reaction - Answers✔Precipitation
Bone marrow stain - Answers✔Romansky and Prussian Blue
Rise in titers - Answers✔Significant in serological testing
Secondary Response - Answers✔IgG
Most common coag inhibitor - Answers✔Lupus inhibitor
3' end - Answers✔OH
Haptens are only antigenic when coupled with - Answers✔Proteins
5' end - Answers✔Phosphate
RA - Answers✔IgE
Most pathogens enter through - Answers✔Mucous membranes
Increased Megakaryocytes in bone marrow decreased platelets - Answers✔Folic Acid Def
Autoimmune disease mechanism - Answers✔Circulating immune complexes
Cells Positive acid phosphatase, not inhibited with tartate - Answers✔Hairy Cell Leukemia
Most common SLE - Answers✔nuclear antigen
Light Chains - Answers✔Kappa/Lamda
Mononucleosis - Answers✔False positive RPR
Negative Glucose oxidase and positive reducing sugars - Answers✔Non-glucose reducing sugars
such as galactose
Hep B vaccine - Answers✔Passive Immunity
Titer - Answers✔Recipricol of maximum reactive dilution
Decreased complement - Answers✔In lupus
Clinical signs of HIV but AB test are negative - Answers✔Window phase before AB production
1
, ©FYNDLAY.
Lymphokine - Answers✔Soluable mediator produced by lymphocytes
Increased protein in urine - Answers✔renal disease
Bethseda Assay - Answers✔Used to quantify coagulation inhibitor
Platelet neutralization - Answers✔Used to see if a patient has a lupus anticoagulant.
ITP - Answers✔Ages 2-4
Spherocytes - Answers✔Membrane defect, Increased destruction of RBCs, caused by
intracorpuscular abnormality
Ependymal clump - Answers✔
MCH range - Answers✔27-33
MCHC - Answers✔33-36%
Manual Platelet count Microscope - Answers✔Phase contrase
A.A decreased in patients with sickle cell - Answers✔L-glutamine
Chediak Higashi Syndrome - Answers✔Albino, Photophobia, pyonic infections, giant dark
granules in neutrophils and monocytes
Aspirin - Answers✔Not likely to cause an abnormal thrombin time
RBCs are usually smaller - Answers✔than the nucleus of a lymphocyte
-a/aa - Answers✔silent carrier
CD20 - Answers✔B cell marker
Platelets - Answers✔do not circulate in inactive form, Spiny sticky form become activated in
response to blood vessel damage
Hemoglobin Chromosome 16 - Answers✔Alpha zeta
Hemoglobin Chromosome 11 - Answers✔beta, delta, episilon and gamma
Megaloblastic anemia - Answers✔Oval microcytes and Hypersegmented neutrophils
Doesn't soley develop in the bone marrow - Answers✔Lymphocytes
Transferrin Saturation - Answers✔(serum Iron/TIBC)X100
Beta Thalasemia minor - Answers✔B+/B, B0/B
Howell-Jolly bodies are composed of - Answers✔DNA
2
, ©FYNDLAY.
CLL CD - Answers✔CD19, CD20, CD23, co-expression of CD5
ADAMTS13 enzyme - Answers✔Cleaving ultalarge molecules of von willebrand factor to keep
them out of circulation
Least likely to stimulate production of reactive lymphocytes - Answers✔HIV
Why ferritin is less than optimal for HH - Answers✔It is an acute phase reactant that is elevated
in a variety of clinical conditions
Barr Bodies - Answers✔Normal in Females not in males
Hexose monophosphate shunt - Answers✔Provide Reduced glutathione to prevent oxidation of
hemoglobin
CML Vs Leukmoid Reaction - Answers✔LAP stain
Aquired Hemophilia A - Answers✔Anti-Factor VIII inhibitor
HbS Protection against Sickling - Answers✔HbF
Absolute Cell count - Answers✔Total count X % of cells counted
Early abnormality in lymph node of AIDS patient - Answers✔Reactive Lymphadenopathy
Clinical symptom thrombocytopenia - Answers✔Petechiae
Lymphocyte - Answers✔Pale-Blue Cytoplasm, Nucleus oval or round
Monocyte - Answers✔Blue-Gray opaque cytoplasm, Nucleus convolutions
Newborns will develop 30% of what HB in HbH - Answers✔Bart
Abnormal Granulation - Answers✔Alder anomaly & Chediak-Higashi
Hemoglobinopathies can not be caused by - Answers✔The deletion of a global chain
Hemolytic anemia - Answers✔Not where basophilic stippling is found
Alpha Thalassemia - Answers✔Decrease in the rate of production of Alpha chains due to partial
or total deletion of the genetic code
Which is NOT associated with Macrocytosis - Answers✔Thalassemia
Warfarin inhibits vitamin K dependent factors - Answers✔2,7,9,10
Flow cytometry is NOT a useful tool in - Answers✔Hepatitis
Clot would have most of an effect on - Answers✔Platelets
3
