Complete Verified Solutions.
AIDS/HIV - Answer profound immunosuppression, opportunistic infections, malignancies, wasting, and
CNS degeneration
HIV type 1 - Answer most infectious worldwide, multiple strains/mutations present
- US, Europe, Central Africa
HIV type 2 - Answer endemic in West Africa, rarley seen in other parts of the world, multiple
strains/mutations present
transmission of HIV - Answer sexual transmission and blood
retrovirus - Answer selectively attacks CD4+ T lymphocytes which coordinate immune response
Sexual transmission - Answer most common mode of transmission
-people with other STDs have increase risk of aquiring HIV
contact with blood/blood products - Answer needles, syringes, straws
-tranfusions of blood before 1985 resulted in HIV
perinatal transmission - Answer most common way that child becomes infected, transmitted through
utero or breast feeding
occupational HIV infection - Answer Universal blood and body fluid precautions should be followed
with ALL patients
-needle sticks
seroconversion - Answer being negative for HIV antibodies to being positive
, window period - Answer time after infection and before seroconversion
-HIV test will result in negative
where does HIV carry genetic info - Answer in RNA
integration - Answer new DNA enters nucleus of CD4+ cells and inserted into cell's original DNA
cleavage - Answer protease enzyme cuts polyprotein chain into individual protiens that will make up
new virus
HIV replication - Answer involves killing CD4+ cells and T-cells and the release of HIV copies into the
bloodstream progressing the infection
progression of HIV/AIDS - Answer CD4+ cell count gradually decreases and number of viruses in blood
increases (viral load)
clinical category A - Answer asymptomatic/persistent lymphadenopathy or symptoms of HIV infection
clinical category B - Answer symptoms immune deficiency not serious enough to be AIDS defining
clinical category C - Answer AIDS- defining illnesses that are listed in the AIDS surveillance case
defintion
primary phase - Answer acute mono like symptoms
-fever, fatigue, myalgias, sore throat, night sweats, rash, GI problems FEVER AND MALAISE most common
chronic/asymptomatic/latency phase - Answer no signs or symptoms, median time of this period is 10
years, CD4+ T cell count gradually falls