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OCCTH 585 TEST 2 QUESTIONS
LATEST 2024-2025 AND CORRECT
DETAILED ANSWERS (VERIFIED
ANSWERS) |ALREADY GRADED A+
Dementia is an umbrella term that includes what 4 neurological diseases?
ANS:
✓ Alzheimer's disease
✓ Vascular dementia
✓ Frontotemporal dementia
✓ Lewy Bodies
What are 4 characteristics of Alzheimer's disease (AD)?
ANS:
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✓ •Not a process of accelerated brain aging
✓ •Specific characteristics in neurons
✓ •Insidious onset (if someone has changes in a day or 2 it is not AD)
✓ •cognitive and behavioral impairments; personality changes
AD early signs
ANS:
✓ - memory loss
✓ - misplacing items often
✓ - mood changes without any stimulation
✓ - should have issues with normal ADL tasks
✓ - vision -- visual tract from frontal, temporal to occipital -- can affect
visual tract (perception) not peripheral vision more the central visual
processing
✓ - struggling to communicate (frontal dementia - broca area) -- trouble
expressing ideas
✓ - clients still have insight to these changes in the beginning
✓ - poor judgment
✓ - confusion of time and place
✓ - social withdrawal
In people with AD, dendritic changes and neurocortical degeneration is resulting
from what 3 main causes?
ANS:
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✓ 1) Neuritic plaques (Senile plaques) (β-amyloid) - appears in normal
aging - but would expect more in AD
✓ - Develop in the parenchyma of the brain
✓ - Not strictly intraneuronal, extracellular structures
✓ - Extracellular deposits of amyloid beta in the grey matter of the brain
✓
✓ 2) Neurofibrillary tangles (tau)
✓ - tau protein
✓ - Strictly intraneuronal
✓ - Lead to the death of neuron
✓ - Specific to AD
✓
✓ 3) Due to abnormality in the metabolism of two distinctive proteins
Beta amyloid plaques
ANS:
✓ occurs in normal aging --especially over the age of 80 -- not a big
difference of people with AD vs normal aging brain -- however may
have a lower prevalence rate and lower number of plaques
✓
✓ discrete spherical lesions
✓ consist mostly of beta amyloid peptide or amyloid plaques
how does B-amyloid plaques form?
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ANS:
✓ -Defective breakdown of a benign substance known as amyloid
precursor protein (APP), integral membrane protein concentrated in
the synapses of neurons
✓ (occurs outside of the neurons)
✓
✓ -Produce sticky insoluble shards of β-amyloid plaques -> stick together
(form clusters), form dense plaques, -> damage axons
Which lobe is most severely affected by plaques?
ANS:
✓ temporal
Hippocampus volume is reduced by up to ____% in advanced AD (reduced
connectivity of the hippocampus with other brain areas)
And the volume of the Amygdala in Advanced AD is reduced by ____%
ANS:
✓ 60%
✓
✓ 45%
Examstudy - Stuvia US | Wednesday, 18 December 2024