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MICR 4423 EXAM 2 CABEEN QUESTIONS AND ANSWERS

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MICR 4423 EXAM 2 CABEEN QUESTIONS AND ANSWERS

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MICR 4423 EXAM 2 CABEEN QUESTIONS AND
ANSWERS
what makes a good antibiotic target - Answers - - the structure is different between
bacteria and host
- structure is important/essential for the bacteria

between gram + and gram - bacteria, which is typically most resistant to antibiotics and
why - Answers - gram -
presence of outer membrane

what is the cell wall made of - Answers - peptidoglycan

the cell wall is made up of ______________ strands and is held together by
_________________ cross-bridges - Answers - glycan, peptide

the cell protects against what - Answers - turgor pressure

which has more elasticity: glycan strands or peptide cross bridges - Answers - peptide
cross bridges

what does NAG stand for - Answers - N-acetyl glucosamine

what does NAM stand for - Answers - N-acetyl muramic acid

what makes up glycan strands - Answers - NAG and NAM

name the components of the pentapeptide in order of how they come off the NAM -
Answers - L-alanine
D-glutamic acid
DAP
D-ala
D-ala

what is the role of transglycosylases - Answers - polymerize glycan strands

what is the role of transpeptidases - Answers - form peptide cross bridges

what type of linkage is commonly formed between adjacent pentapeptides - Answers -
3, 4

what two enzymes are required to revert bactoprenol back to its original state - Answers
- phosphatase and flippase

what was the first beta-lactam antibiotic discovered - Answers - isopenicillin N

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