©SIRJOEL EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
NU 345 Exam 1 Study Guide.
MAOI's - Answers✔antidepressant
monoamine oxidase inhibitors
MAOI action - Answers✔impending the destruction/breakdown of the neurotransmitter
serotonin
MAOI examples - Answers✔Isocarboxazid, phenelzine, tranyclypromine, selegine transdermal
patch
caution with MAOI's - Answers✔elevated tyramine levels coudl couse a hypertensive crisis
NO wine, aged cheese, chocolate, beer, nuts
tricyclics - Answers✔antidepressant
tricyclic action - Answers✔blocks the reuptake of norepinephrine and serotonin
tricyclic examples - Answers✔amoxapine, amitripytline, clomipramine, desipramine, doxepin,
imipramine, notriptyline, protripytline, trimioramine
tricyclic side effects - Answers✔anti-cholinergic (can't see, can't pee, can't spit, can't poop)
1|Page
, ©SIRJOEL EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
caution with tricyclics - Answers✔toxicity is huge risk. lethal in OD
SSRI's - Answers✔antidepressant
considered first tx of choice for depression & anxiety
selective serotonin reuptake inhibitors
SSRI action - Answers✔inhibits the reuptake of serontonin which increases serotinon levels at
the synapse resulting in elevated mmod
SSRI examples - Answers✔citalopram (celexa), escitalopram (lexapro), fluoxetine (prozac),
fluvoxamine (luvox), paroxetine (paxil), sertraline (zoloft)
SSRI side effects - Answers✔weight gain & sexual dysfunction
caution with SSRI - Answers✔serotonin syndrome; confusion, agitation, hypomania,
tachycardia, BP instability, hyperreflexia, rigidity, restlessness, tremors, ataxia, diaphoresis,
increased respirations, elevated temp, nonreactive pupil
SNRI's - Answers✔atypical antidepressant
serotonin & norepinephrine reuptake inhibitors
SNRI action - Answers✔works very similar to SSRI's but acts on both neurotransmitters
(serontonin & norepinephrine)
SNRI examples - Answers✔desvenlafaxene (pristiq), venlafaxine (effexor), duloxetine (cymbalta)
2|Page
ALL RIGHTS RESERVED.
NU 345 Exam 1 Study Guide.
MAOI's - Answers✔antidepressant
monoamine oxidase inhibitors
MAOI action - Answers✔impending the destruction/breakdown of the neurotransmitter
serotonin
MAOI examples - Answers✔Isocarboxazid, phenelzine, tranyclypromine, selegine transdermal
patch
caution with MAOI's - Answers✔elevated tyramine levels coudl couse a hypertensive crisis
NO wine, aged cheese, chocolate, beer, nuts
tricyclics - Answers✔antidepressant
tricyclic action - Answers✔blocks the reuptake of norepinephrine and serotonin
tricyclic examples - Answers✔amoxapine, amitripytline, clomipramine, desipramine, doxepin,
imipramine, notriptyline, protripytline, trimioramine
tricyclic side effects - Answers✔anti-cholinergic (can't see, can't pee, can't spit, can't poop)
1|Page
, ©SIRJOEL EXAM SOLUTIONS 2024/2025
ALL RIGHTS RESERVED.
caution with tricyclics - Answers✔toxicity is huge risk. lethal in OD
SSRI's - Answers✔antidepressant
considered first tx of choice for depression & anxiety
selective serotonin reuptake inhibitors
SSRI action - Answers✔inhibits the reuptake of serontonin which increases serotinon levels at
the synapse resulting in elevated mmod
SSRI examples - Answers✔citalopram (celexa), escitalopram (lexapro), fluoxetine (prozac),
fluvoxamine (luvox), paroxetine (paxil), sertraline (zoloft)
SSRI side effects - Answers✔weight gain & sexual dysfunction
caution with SSRI - Answers✔serotonin syndrome; confusion, agitation, hypomania,
tachycardia, BP instability, hyperreflexia, rigidity, restlessness, tremors, ataxia, diaphoresis,
increased respirations, elevated temp, nonreactive pupil
SNRI's - Answers✔atypical antidepressant
serotonin & norepinephrine reuptake inhibitors
SNRI action - Answers✔works very similar to SSRI's but acts on both neurotransmitters
(serontonin & norepinephrine)
SNRI examples - Answers✔desvenlafaxene (pristiq), venlafaxine (effexor), duloxetine (cymbalta)
2|Page
