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MAOI's - ✔✔antidepressant
monoamine oxidase inhibitors
MAOI action - ✔✔impending the destruction/breakdown of the
neurotransmitter serotonin
MAOI examples - ✔✔Isocarboxazid, phenelzine, tranyclypromine, selegine
transdermal patch
caution with MAOI's - ✔✔elevated tyramine levels coudl couse a
hypertensive crisis
NO wine, aged cheese, chocolate, beer, nuts
tricyclics - ✔✔antidepressant
tricyclic action - ✔✔blocks the reuptake of norepinephrine and serotonin
tricyclic examples - ✔✔amoxapine, amitripytline, clomipramine,
desipramine, doxepin, imipramine, notriptyline, protripytline, trimioramine
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, tricyclic side effects - ✔✔anti-cholinergic (can't see, can't pee, can't spit,
can't poop)
caution with tricyclics - ✔✔toxicity is huge risk. lethal in OD
SSRI's - ✔✔antidepressant
considered first tx of choice for depression & anxiety
selective serotonin reuptake inhibitors
SSRI action - ✔✔inhibits the reuptake of serontonin which increases
serotinon levels at the synapse resulting in elevated mmod
SSRI examples - ✔✔citalopram (celexa), escitalopram (lexapro), fluoxetine
(prozac), fluvoxamine (luvox), paroxetine (paxil), sertraline (zoloft)
SSRI side effects - ✔✔weight gain & sexual dysfunction
caution with SSRI - ✔✔serotonin syndrome; confusion, agitation,
hypomania, tachycardia, BP instability, hyperreflexia, rigidity, restlessness,
tremors, ataxia, diaphoresis, increased respirations, elevated temp,
nonreactive pupil
SNRI's - ✔✔atypical antidepressant
serotonin & norepinephrine reuptake inhibitors
SNRI action - ✔✔works very similar to SSRI's but acts on both
neurotransmitters (serontonin & norepinephrine)
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©JOSHCLAY 2024/2025. YEAR PUBLISHED 2024.