PCol Module 1 Exam with Correct
Solutions
Pharmacology - correct answer-Study of substances that interact with living systems
through chemical processes, especially by binding to regulatory molecules and
activating or inhibiting normal body processes.
Beneficial therapeutic effect or toxic effects - correct answer-two effects of drugs in
patient and microorganism
Medical Pharmacology - correct answer-is defined as the science of substances used to
prevent, diagnose, and treat disease.
Toxicology - correct answer-is the branch of pharmacology that deals with the
undesirable effects of chemicals on living systems, from individual cells to humans to
complex ecosystem.
Materia Medica -> Francois Magendie and Claude Bernard (experimental physiology
and pharmacology) -> New concepts about drug action and biologic substrate (drug
receptor) -> Introduction to pharmacogenomics - correct answer-History of
Pharmacology (4)
Materia Medica - correct answer-Precursor to pharmacology
small interfering RNAs (siRNAs)
microRNAs (miRNAs) - correct answer-Investigation of _______________ and
_______________ as therapeutic agents (advances in the therapeutic)
antisense oligonucleotides (ANOs) - correct answer-Short nucleotide chains are called?
Drug - correct answer-It may be defined as any substance that brings about a change in
biologic function through its chemical actions
Agonist - correct answer-A drug that acts as activator of a specific molecule
Antagonist - correct answer-A drug that acts as inhibitor of a specific molecule
Xenobiotics - correct answer-What do you call chemicals not synthesized in the body?
Poison - correct answer-refers to a drug that have almost exclusively harmful effects.
, Dose - correct answer-The _______ of the drug makes the poison (Paracelsus)
Toxin - correct answer-which refers to poison of biologic origin and is usually
synthesized by plants or animals.
True - correct answer-T or F?
Can drug become solid, liquid, or gas. And can it be organic and inorganic?
100 MW - correct answer-To achieve selective binding, the drug molecule should be at
least _____ units in size.
1000 - correct answer-Drugs with MW greater than ________ do not diffuse readily
between compartments, so must be administered directly into the compartment where
they have their effect.
Covalent bond - correct answer-type of bond that is very strong and not reversible.
Aspirin (acetyl group) and cyclooxygenase - correct answer-__________ and
___________ is an example of covalent bond
Electrostatic - correct answer-type of bond that vary from relatively strong linkages
between permanently charged ionic molecules to weaker hydrogen bonds and very
weak induced dipole forces
Hydrophobic - correct answer-type of bond that is usually quite weak; it is the interaction
of highly lipid-soluble drugs with the lipids of the cell membrane
S(-) - correct answer-Which is a potent beta blocker (chirality)? S(-) carvedilol or the
R(+)?
+ enantiomer - correct answer-Which enantiomer of ketamine is more potent and is less
toxic? + or -?
Pharmacokinetics and Pharmacodynamics - correct answer-Two main division of
pharmacology
PHARMACOTHERAPEUTICS (PHARMACOTHERAPY) - correct answer-the study of
the use of drugs to treat diseases.
PHARMACOKINETICS - correct answer-Is the study of how the body absorbs,
distributes, metabolizes, and excretes drugs
Solutions
Pharmacology - correct answer-Study of substances that interact with living systems
through chemical processes, especially by binding to regulatory molecules and
activating or inhibiting normal body processes.
Beneficial therapeutic effect or toxic effects - correct answer-two effects of drugs in
patient and microorganism
Medical Pharmacology - correct answer-is defined as the science of substances used to
prevent, diagnose, and treat disease.
Toxicology - correct answer-is the branch of pharmacology that deals with the
undesirable effects of chemicals on living systems, from individual cells to humans to
complex ecosystem.
Materia Medica -> Francois Magendie and Claude Bernard (experimental physiology
and pharmacology) -> New concepts about drug action and biologic substrate (drug
receptor) -> Introduction to pharmacogenomics - correct answer-History of
Pharmacology (4)
Materia Medica - correct answer-Precursor to pharmacology
small interfering RNAs (siRNAs)
microRNAs (miRNAs) - correct answer-Investigation of _______________ and
_______________ as therapeutic agents (advances in the therapeutic)
antisense oligonucleotides (ANOs) - correct answer-Short nucleotide chains are called?
Drug - correct answer-It may be defined as any substance that brings about a change in
biologic function through its chemical actions
Agonist - correct answer-A drug that acts as activator of a specific molecule
Antagonist - correct answer-A drug that acts as inhibitor of a specific molecule
Xenobiotics - correct answer-What do you call chemicals not synthesized in the body?
Poison - correct answer-refers to a drug that have almost exclusively harmful effects.
, Dose - correct answer-The _______ of the drug makes the poison (Paracelsus)
Toxin - correct answer-which refers to poison of biologic origin and is usually
synthesized by plants or animals.
True - correct answer-T or F?
Can drug become solid, liquid, or gas. And can it be organic and inorganic?
100 MW - correct answer-To achieve selective binding, the drug molecule should be at
least _____ units in size.
1000 - correct answer-Drugs with MW greater than ________ do not diffuse readily
between compartments, so must be administered directly into the compartment where
they have their effect.
Covalent bond - correct answer-type of bond that is very strong and not reversible.
Aspirin (acetyl group) and cyclooxygenase - correct answer-__________ and
___________ is an example of covalent bond
Electrostatic - correct answer-type of bond that vary from relatively strong linkages
between permanently charged ionic molecules to weaker hydrogen bonds and very
weak induced dipole forces
Hydrophobic - correct answer-type of bond that is usually quite weak; it is the interaction
of highly lipid-soluble drugs with the lipids of the cell membrane
S(-) - correct answer-Which is a potent beta blocker (chirality)? S(-) carvedilol or the
R(+)?
+ enantiomer - correct answer-Which enantiomer of ketamine is more potent and is less
toxic? + or -?
Pharmacokinetics and Pharmacodynamics - correct answer-Two main division of
pharmacology
PHARMACOTHERAPEUTICS (PHARMACOTHERAPY) - correct answer-the study of
the use of drugs to treat diseases.
PHARMACOKINETICS - correct answer-Is the study of how the body absorbs,
distributes, metabolizes, and excretes drugs
