Midterm: Which of the following descriptions of human male gametes is incorrect?
a) Haploid
b) Homogametic
c) Hemizygous
d) Contains X or Y chromosomes
e) Fertilized a female gamete to form a zygote - ANSWER b) Homogametic
Midterm: Select the inaccurate statement.
a) Chromosomes are loosely packaged in M phase
b) The "beads-on-sting" conformation of DNA packaging is easily transcribed
c) Mitotic chromosomes are considered transcriptionally inactive
d) Histones are proteins that package DNA into heterochromatin
e) Centromeres are examples of DNA packaged into heterochromatin - ANSWER a)
Chromosomes are loosely packaged in M phase
Midterm: Select the most accurate statement. Human chromosomes:
a) Consist of 1 molecule of DNA before S phase of the cell cycle
b) Consists of 2 molecules of DNA before S phase of the cell cycle
c) Consists of 1 molecule of DNA after S phase of the cell cycle
d) Are located within the cytoplasm of the cell
e) None of the above statements are correct - ANSWER a) Consist of 1 molecule of
DNA before S phase of the cell cycle
Midterm: What is the mode of inheritance in this pedigree?
a) Y-linked inheritance
b) X-linked recessive inheritance
c) X-linked dominant inheritance
d) Autosomal recessive inheritance
e) Autosomal dominant inheritance - ANSWER e) Autosomal dominant inheritance
Midterm: Individual IV-4 marries an unaffected woman. What is the probability that their
first child will be phenotypically normal?
a) 1/2 chance that the first child will be phenotypically normal
b) 1/3 chance that the first child will be phenotypically normal
c) 3/4 chance the first female will be phenotypically normal; all male children will be
phenotypically normal
d) 1/8 chance that the first child will be phenotypically normal
, e) 7/8 chance the first male will be phenotypically normal; all female will be
phenotypically normal - ANSWER a) 1/2 chance that the first child will be phenotypically
normal
Which one of the following is an example of this mode of inheritance?
a) Albanism
b) Marfan Syndrome
c) Coffin-Lowry Syndrome
d) Male Infertility
e) Heamophilia - ANSWER b) Marfan Syndrome
Is the following statement correct or incorrect? An infant born with Patau Syndrome
have an extra copy of chromosome 18, suffer severe neurological developmental
deficiencies and have a short life expectancy.
a) correct
b) incorrect - ANSWER b) incorrect
Midterm: Select the most accurate statement:
a) classic haemophilia occurs to severe decrease in blood clotting factor IX
b) Treatments of haemophilia are restricted to blood transfusions
c) Haemophiliacs have decreased ability to produce fibrin needed for blood clot
formation
d) Christmas Disease occurs due to severe decrease in blood clotting factor VIII
e) All of the above are correct - ANSWER c) Haemophiliacs have decreased ability to
produce fibrin needed for blood clot formation
Midterm: Select the correct statement. The exchange of genetic material via
chromosomal cross-over occurs only during:
a) Prophase of mitosis
b) Prophase of mitosis ad both prophases of meiosis
c) Prophase I of meiosis
d) Prophase II of meiosis
e) Metaphase I of meiosis - ANSWER c) Prophase I of meiosis
Midterm: How many chromatids would be found in a primary oocyte during Prophase I?
a) 23
b) 46
c) 69
d) 92
e) none of the above - ANSWER d) 92