Chapter 37 Anticancer Drugs
MULTIPLE CHOICE
1. A patient who has been instructed to use a liquid antacid medication to treat gastrointestinal
upset asks the nurse about how to take this medication. What information will the nurse
include when teaching this patient?
a. Take a laxative if constipation occurs.
b. Take 60 minutes after meals and at bedtime.
c. Take with at least 8 ounces of water to improve absorption.
d. Take with milk to improve effectiveness.
ANS B
Since maximum acid secretion occurs after eating and at bedtime, antacids should be taken 1 to
3 hours after eating and at bedtime. Taking antacids before meals slows gastric emptying time
and causes increased gastrointestinal (GI) secretions. Patients should not self-treat constipation
or diarrhea. Patients should use 2 to 4 ounces of water when taking to ensure that the drug
enters the stomach; more than that will increase GI secretions. Antacids should not be taken
with milk or foods high in vitamin D.
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MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
2. A patient who has symptoms of peptic ulcer disease will undergo a test that requires drinking
a liquid containing 13C urea and breathing into a container. The nurse will explain to the
patient that this test is performed to
a. assess the level of hydrochloric acid.
b. detect H. pylori antibodies.
c. measure the pH of gastric secretions.
d. test for the presence of 13CO2.
ANS D
When H. pylori is suspected, a noninvasive test is performed by administering 13C urea
which, in the presence of H. pylori, will release 13CO2. The test does not measure the amount
of HCl acid or the pH and does not detect H. pylori antibodies.
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MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
3. A patient is taking esomeprazole (Nexium) 15 mg per day to treat a duodenal ulcer. After
10 days of treatment, the patient reports that the pain has subsided. The nurse will counsel the
patient to
a. continue the medication for 4 more weeks.
b. reduce the medication dose by half.
c. stop taking the medication.
, d. take the medication every other day.
ANS A
With treatment, ulcer pain may subside in 10 days, but the healing process may take 1 to 2
months. Patients should be counseled to take the drug for the length of time prescribed.
Reducing the dose or taking less frequently is not indicated.
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MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
4. A patient with a peptic ulcer has been diagnosed with H. pylori. The provider has ordered
lansoprazole (Prevacid), clarithromycin (Biaxin), and metronidazole (Flagyl). The patient
asks the nurse why two antibiotics are needed. The nurse will explain that two antibiotics a.
allow for less toxic dosing.
b. combat bacterial resistance.
c. have synergistic effects.
d. improve acid suppression.
ANS B
The use of two antibiotics when treating H. pylori peptic ulcer disease helps to combat bacterial
resistance because H. pylori develops resistance rapidly. Giving two antibiotics, in this case, is
not to reduce the dose or to cause synergistic effects. Antibiotics do not affect acid production.
DIF COGNITIVE LEVEL Understanding (Comprehension) REF dm 695 TOP
NURSING PROCESS Nursing Intervention Patient Teaching
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
5. A patient who takes propantheline bromine (Pro-Banthine) and omeprazole (Prilosec) for an
ulcer will begin taking an antacid. The nurse will give which instruction to the patient
regarding how to take the antacid?
a. Take the antacid 2 hours after taking the propantheline.
b. Take the antacid along with a meal.
c. Take the antacid with milk.
d. Take the antacid with the propantheline bromine.
ANS A
Antacids can slow the absorption of anticholinergics and should be taken 2 hours after
anticholinergic administration. Antacids should be given 1 to 3 hours after a meal and should
not be given with dairy products.
DIF COGNITIVE LEVEL Applying (Application) REF dm 699 TOP
NURSING PROCESS Nursing Intervention
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
6. Which antacid is likely to cause acid rebound?
a. Aluminum hydroxide
b. Calcium carbonate
MULTIPLE CHOICE
1. A patient who has been instructed to use a liquid antacid medication to treat gastrointestinal
upset asks the nurse about how to take this medication. What information will the nurse
include when teaching this patient?
a. Take a laxative if constipation occurs.
b. Take 60 minutes after meals and at bedtime.
c. Take with at least 8 ounces of water to improve absorption.
d. Take with milk to improve effectiveness.
ANS B
Since maximum acid secretion occurs after eating and at bedtime, antacids should be taken 1 to
3 hours after eating and at bedtime. Taking antacids before meals slows gastric emptying time
and causes increased gastrointestinal (GI) secretions. Patients should not self-treat constipation
or diarrhea. Patients should use 2 to 4 ounces of water when taking to ensure that the drug
enters the stomach; more than that will increase GI secretions. Antacids should not be taken
with milk or foods high in vitamin D.
DIF COGNITIVE LEVEL Applying (Application) REF dm 698 TOP
NURSING PROCESS Nursing Intervention Teaching
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
2. A patient who has symptoms of peptic ulcer disease will undergo a test that requires drinking
a liquid containing 13C urea and breathing into a container. The nurse will explain to the
patient that this test is performed to
a. assess the level of hydrochloric acid.
b. detect H. pylori antibodies.
c. measure the pH of gastric secretions.
d. test for the presence of 13CO2.
ANS D
When H. pylori is suspected, a noninvasive test is performed by administering 13C urea
which, in the presence of H. pylori, will release 13CO2. The test does not measure the amount
of HCl acid or the pH and does not detect H. pylori antibodies.
DIF COGNITIVE LEVEL Understanding (Comprehension) REF dm 695 TOP
NURSING PROCESS Assessment/Nursing Intervention
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
3. A patient is taking esomeprazole (Nexium) 15 mg per day to treat a duodenal ulcer. After
10 days of treatment, the patient reports that the pain has subsided. The nurse will counsel the
patient to
a. continue the medication for 4 more weeks.
b. reduce the medication dose by half.
c. stop taking the medication.
, d. take the medication every other day.
ANS A
With treatment, ulcer pain may subside in 10 days, but the healing process may take 1 to 2
months. Patients should be counseled to take the drug for the length of time prescribed.
Reducing the dose or taking less frequently is not indicated.
DIF COGNITIVE LEVEL Applying (Application) REF dm 695
TOP NURSING PROCESS Nursing Intervention Patient Teaching
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
4. A patient with a peptic ulcer has been diagnosed with H. pylori. The provider has ordered
lansoprazole (Prevacid), clarithromycin (Biaxin), and metronidazole (Flagyl). The patient
asks the nurse why two antibiotics are needed. The nurse will explain that two antibiotics a.
allow for less toxic dosing.
b. combat bacterial resistance.
c. have synergistic effects.
d. improve acid suppression.
ANS B
The use of two antibiotics when treating H. pylori peptic ulcer disease helps to combat bacterial
resistance because H. pylori develops resistance rapidly. Giving two antibiotics, in this case, is
not to reduce the dose or to cause synergistic effects. Antibiotics do not affect acid production.
DIF COGNITIVE LEVEL Understanding (Comprehension) REF dm 695 TOP
NURSING PROCESS Nursing Intervention Patient Teaching
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
5. A patient who takes propantheline bromine (Pro-Banthine) and omeprazole (Prilosec) for an
ulcer will begin taking an antacid. The nurse will give which instruction to the patient
regarding how to take the antacid?
a. Take the antacid 2 hours after taking the propantheline.
b. Take the antacid along with a meal.
c. Take the antacid with milk.
d. Take the antacid with the propantheline bromine.
ANS A
Antacids can slow the absorption of anticholinergics and should be taken 2 hours after
anticholinergic administration. Antacids should be given 1 to 3 hours after a meal and should
not be given with dairy products.
DIF COGNITIVE LEVEL Applying (Application) REF dm 699 TOP
NURSING PROCESS Nursing Intervention
MSC NCLEX Physiological Integrity Pharmacological and Parenteral Therapies
6. Which antacid is likely to cause acid rebound?
a. Aluminum hydroxide
b. Calcium carbonate
