COMSAE 110/ 152 Completely Solved
Questions/ A+ Score Solution.
Wernicke aphasia - Answer: Fluent aphasia
-impaired comprehension & repetition
-word salad
-superior temporal gyrus
-Brodmann area 22
-MCA
Broca aphasia - Answer: Non-fluent aphasia
-can repeat & comprehend
-inferior frontal gyrus
-Brodmann areas 44 & 45
-MCA
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,Conduction aphasia - Answer: Can't repeat
-are fluent & can comprehend
-arcuate fasciculus (supramarginal gyrus)
-MCA
Global aphasia - Answer: Can't speak, comprehend or repeat
-Mainstem MCA
Gastric ulcers:
pain
H. pylori
mechanism
other causes
risk of carcinoma - Answer: Pain greater w/ meals = weight loss
H. pylori common
Mech = dec mucosal protection against gastric acid
Other causes = NSAIDs
Risk of carcinoma increases
Duodenal ulcer:
pain
H. pylori
mechanism
other causes
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,risk of carcinoma - Answer: Pain lesser w/ meals = weight gain
No H. pylori
Mech = dec mucosal protection/increased gastric acid
Other causes = Zollinger-Ellison
Risk of carcinoma no
Krukenberg tumor - Answer: Gastric adenocarcinoma that mets to ovary
-abundant mucin-secreting signet ring cells
Chron disease:
Location
Gross morphology
Micro morphology
Complications (3)
Diarrhea
ExtraGI manifestations (4)
Tx (4) - Answer: Location = all GI, terminal ileum & colon, skip lesions, rectal
sparing
Gross morphology = transmural, fistulas, cobblestone mucosa, creeping fat, string
sign, linear ulcers & fissures
Micro morphology = noncaseating granulomas
Complications (3) = malabsorption, fistulas, & strictures
Diarrhea = may NOT be bloody
ExtraGI manifestations (4) = rash, oral ulcers, Ca2+ oxalate stones, & anti-
Saccharomyces cervisiae Abs (ASCA)
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, Tx = glucocorticoids, AZA, Abx (cipro & metronidazole) biologics (infliximab,
adalimumab)
Ulcerative colitis:
Location
Gross morphology
Micro morphology
Complications (3)
Diarrhea
ExtraGI manifestations (4)
Tx (4) - Answer: Location = colon, continuous, involves rectum
Gross morphology = mucosal & submucosal only, friable, loss of haustra (lead
pipe) appearance
Micro morphology = crypt abscesses, bleeding
Complications (3) = malabsorption, toxic megacolon, & perforation
Diarrhea = bloody
ExtraGI manifestations (4) = rash, oral ulcers, primary sclerosing cholangitis, &
MPO-ANCA/p-ANCA
Tx (4) = 5-aminosalicylic acid prep (mesalamine), 6-MP, infliximab, & colectomy
Alpha hemolytic optochin sensitive strep - Answer: Strep pneumo
Strep pneumo VF (1) & common infections (4) - Answer: VF = IgA protease
Causes: Meningitis, Otitis media, Pneumonia, Sinusitis (MOPS)
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Questions/ A+ Score Solution.
Wernicke aphasia - Answer: Fluent aphasia
-impaired comprehension & repetition
-word salad
-superior temporal gyrus
-Brodmann area 22
-MCA
Broca aphasia - Answer: Non-fluent aphasia
-can repeat & comprehend
-inferior frontal gyrus
-Brodmann areas 44 & 45
-MCA
Page 1 of 33
,Conduction aphasia - Answer: Can't repeat
-are fluent & can comprehend
-arcuate fasciculus (supramarginal gyrus)
-MCA
Global aphasia - Answer: Can't speak, comprehend or repeat
-Mainstem MCA
Gastric ulcers:
pain
H. pylori
mechanism
other causes
risk of carcinoma - Answer: Pain greater w/ meals = weight loss
H. pylori common
Mech = dec mucosal protection against gastric acid
Other causes = NSAIDs
Risk of carcinoma increases
Duodenal ulcer:
pain
H. pylori
mechanism
other causes
Page 2 of 33
,risk of carcinoma - Answer: Pain lesser w/ meals = weight gain
No H. pylori
Mech = dec mucosal protection/increased gastric acid
Other causes = Zollinger-Ellison
Risk of carcinoma no
Krukenberg tumor - Answer: Gastric adenocarcinoma that mets to ovary
-abundant mucin-secreting signet ring cells
Chron disease:
Location
Gross morphology
Micro morphology
Complications (3)
Diarrhea
ExtraGI manifestations (4)
Tx (4) - Answer: Location = all GI, terminal ileum & colon, skip lesions, rectal
sparing
Gross morphology = transmural, fistulas, cobblestone mucosa, creeping fat, string
sign, linear ulcers & fissures
Micro morphology = noncaseating granulomas
Complications (3) = malabsorption, fistulas, & strictures
Diarrhea = may NOT be bloody
ExtraGI manifestations (4) = rash, oral ulcers, Ca2+ oxalate stones, & anti-
Saccharomyces cervisiae Abs (ASCA)
Page 3 of 33
, Tx = glucocorticoids, AZA, Abx (cipro & metronidazole) biologics (infliximab,
adalimumab)
Ulcerative colitis:
Location
Gross morphology
Micro morphology
Complications (3)
Diarrhea
ExtraGI manifestations (4)
Tx (4) - Answer: Location = colon, continuous, involves rectum
Gross morphology = mucosal & submucosal only, friable, loss of haustra (lead
pipe) appearance
Micro morphology = crypt abscesses, bleeding
Complications (3) = malabsorption, toxic megacolon, & perforation
Diarrhea = bloody
ExtraGI manifestations (4) = rash, oral ulcers, primary sclerosing cholangitis, &
MPO-ANCA/p-ANCA
Tx (4) = 5-aminosalicylic acid prep (mesalamine), 6-MP, infliximab, & colectomy
Alpha hemolytic optochin sensitive strep - Answer: Strep pneumo
Strep pneumo VF (1) & common infections (4) - Answer: VF = IgA protease
Causes: Meningitis, Otitis media, Pneumonia, Sinusitis (MOPS)
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