Midterm Practice Exam) NR 565 midterm: Advanced
pharmacology: MOCK practice Exam
Drugs that APRNs can prescribe - ANSWER:Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - ANSWER:Prescriptive authority
regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
ANSWER:Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
ANSWER:Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - ANSWER:BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site - ANSWER:Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - ANSWER:Reasons for
medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- ANSWER:IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
ANSWER:Oral administration in neonates/infants
Based on body surface area (BSA) calculation - ANSWER:Dosage determination for pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment - ANSWER:Guiding
principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine - ANSWER:CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
ANSWER:Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions - ANSWER:Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - ANSWER:Impacts of polypharmacy
They decrease medication metabolism - ANSWER:CYP450 inhibitors function
, May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - ANSWER:CYP450
inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity - ANSWER:Poor metabolism phenotype
Ensures safety, efficiency, and security of human and veterinary drugs, biological products, and medical
devices - ANSWER:US FDA regulation
Include heroin, oxycodone, methadone, and morphine. - ANSWER:Pure Opioid Agonists
Include naloxone, methylnaltrexone, and naloxegol. - ANSWER:Pure Opioid Antagonists
Include pentazocine, buprenorphine, and nalbuphine. - ANSWER:Agonist-Antagonist Opioids
Predicts overdose risk based on a 5-item measure. - ANSWER:Opioid Risk Tool (ORT)
Database tracking patient's controlled substance history. - ANSWER:Prescription Drug Monitoring
Program
Includes prior overdose, misuse, high doses, and benzodiazepines. - ANSWER:Naloxone Prescription
Criteria
Include attendance drop, secretive behavior, and friend changes. - ANSWER:Behavioral Signs of Drug
Abuse
Include personality change, mood swings, and paranoia. - ANSWER:Psychological Signs of Drug Abuse
High abuse potential requiring written prescriptions. - ANSWER:Schedule II Drugs
Include heroin, LSD, marijuana, and methaqualone. - ANSWER:Schedule I Drugs
Moderate abuse potential, like codeine products and steroids. - ANSWER:Schedule III Drugs
Low abuse potential, like Xanax, Valium, and Ambien. - ANSWER:Schedule IV Drugs
Contain limited narcotics for analgesic purposes. - ANSWER:Schedule V Drugs
Risk of QT prolongation, Torsade's de Pointes, and respiratory depression. - ANSWER:Methadone Black
Box Warning
Improves conditions, reduces risks, and criminal behavior. - ANSWER:Methadone Benefits
Converts to morphine, toxic in children, and breast milk risks. - ANSWER:Codeine Black Box Warning
High abuse potential, fatal respiratory depression risk. - ANSWER:Hydromorphone and Oxymorphone
Warning
High abuse potential, risk of fatal respiratory depression. - ANSWER:Oxycodone Black Box Warning
Contains acetaminophen, associated with hepatotoxicity. - ANSWER:Hydrocodone Black Box Warning
Combination deters misuse, enhances opioid blocking. - ANSWER:Buprenorphine and Naloxone Benefit
For neuropathic pain, seizures, and fibromyalgia. - ANSWER:Pregabalin Use
pharmacology: MOCK practice Exam
Drugs that APRNs can prescribe - ANSWER:Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - ANSWER:Prescriptive authority
regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
ANSWER:Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
ANSWER:Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - ANSWER:BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site - ANSWER:Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - ANSWER:Reasons for
medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- ANSWER:IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
ANSWER:Oral administration in neonates/infants
Based on body surface area (BSA) calculation - ANSWER:Dosage determination for pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment - ANSWER:Guiding
principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine - ANSWER:CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
ANSWER:Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions - ANSWER:Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - ANSWER:Impacts of polypharmacy
They decrease medication metabolism - ANSWER:CYP450 inhibitors function
, May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive - ANSWER:CYP450
inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity - ANSWER:Poor metabolism phenotype
Ensures safety, efficiency, and security of human and veterinary drugs, biological products, and medical
devices - ANSWER:US FDA regulation
Include heroin, oxycodone, methadone, and morphine. - ANSWER:Pure Opioid Agonists
Include naloxone, methylnaltrexone, and naloxegol. - ANSWER:Pure Opioid Antagonists
Include pentazocine, buprenorphine, and nalbuphine. - ANSWER:Agonist-Antagonist Opioids
Predicts overdose risk based on a 5-item measure. - ANSWER:Opioid Risk Tool (ORT)
Database tracking patient's controlled substance history. - ANSWER:Prescription Drug Monitoring
Program
Includes prior overdose, misuse, high doses, and benzodiazepines. - ANSWER:Naloxone Prescription
Criteria
Include attendance drop, secretive behavior, and friend changes. - ANSWER:Behavioral Signs of Drug
Abuse
Include personality change, mood swings, and paranoia. - ANSWER:Psychological Signs of Drug Abuse
High abuse potential requiring written prescriptions. - ANSWER:Schedule II Drugs
Include heroin, LSD, marijuana, and methaqualone. - ANSWER:Schedule I Drugs
Moderate abuse potential, like codeine products and steroids. - ANSWER:Schedule III Drugs
Low abuse potential, like Xanax, Valium, and Ambien. - ANSWER:Schedule IV Drugs
Contain limited narcotics for analgesic purposes. - ANSWER:Schedule V Drugs
Risk of QT prolongation, Torsade's de Pointes, and respiratory depression. - ANSWER:Methadone Black
Box Warning
Improves conditions, reduces risks, and criminal behavior. - ANSWER:Methadone Benefits
Converts to morphine, toxic in children, and breast milk risks. - ANSWER:Codeine Black Box Warning
High abuse potential, fatal respiratory depression risk. - ANSWER:Hydromorphone and Oxymorphone
Warning
High abuse potential, risk of fatal respiratory depression. - ANSWER:Oxycodone Black Box Warning
Contains acetaminophen, associated with hepatotoxicity. - ANSWER:Hydrocodone Black Box Warning
Combination deters misuse, enhances opioid blocking. - ANSWER:Buprenorphine and Naloxone Benefit
For neuropathic pain, seizures, and fibromyalgia. - ANSWER:Pregabalin Use
