WITH FULL COMPLETE QUESTIONS AND 100%
CORRECT ANSWERS |WELL GRADED A+
what birth defect might be present with lithium use? - CORRECT ANSWERS-Epstein’s
anomaly
how do you treat lithium overdose? - CORRECT ANSWERS-*dialysis*
sodium polystyrene sulfonate
what type of bipolar symptoms does valproic acid help? - CORRECT ANSWERS-mania
- less effective with depression
what is the starting dose of lithium? - CORRECT ANSWERS-300mg BID or TID
what types of bipolar patients might benefit most from valproic acid? - CORRECT
ANSWERS-rapid cycling
mixed
patient with comorbid anxiety
comorbid substance use
what lab tests should be monitored with valproic acid? - CORRECT ANSWERS-LFT,
CBC, pregnancy test
what supplement should be started in women of childbearing age who are taking
valproic acid? - CORRECT ANSWERS-folic acid
what is the target blood level of valproic acid? - CORRECT ANSWERS-50-100 mcg/ml
what are side effects of valproic acid? - CORRECT ANSWERS-thrombocytopenia,
pancreatitis, weight gain, hair loss, GI distress, cognitive dulling, neural tube defects in
pregnancy
*weight gain and sedation
- watch for increase in ammonia and transaminitis
what two organs can be impacted by valproic acid? - CORRECT ANSWERS-liver,
pancreas
what birth defects might be observed with valproic acid? - CORRECT ANSWERS-
neural tube defects, cleft palate
what is the first line treatment for acute mania and mania prophylaxis? - CORRECT
ANSWERS-carbamazepine
, what type of bipolar symptoms is carbamazepine best for? - CORRECT ANSWERS-
mania (rapid, mixed)
what are modifiable risk factors for suicide? - CORRECT ANSWERS-- unrealistic
expectations
perfectionism
poor coping skills
what are some warnings signs of suicide? - CORRECT ANSWERS-ideation, substance
use
purposelessness, anxiety, "trapped", hopeless
withdrawal, anger, recklessness, mood changes
what three classes of medication are used as mood stabilizers? - CORRECT
ANSWERS-lithium
anticonvulsants
antipsychotics
what medication can help reduce the risk of suicide? - CORRECT ANSWERS-lithium
what symptoms of bipolar does lithium help? - CORRECT ANSWERS-mania and
depression
what blood tests need to be completed before starting lithium? - CORRECT
ANSWERS-kidney (creatinine), TSH, CBC, pregnancy test
what is the goal blood trough level for lithium? - CORRECT ANSWERS-0.6 - 1.2 mEq/L
what are the most common side effects of lithium use? - CORRECT ANSWERS-GI
upset
weight gain
tremor
hair loss/acne
can cause:
leukocytosis
polyuria/polydipsia secondary to ADH antagonism
thyroid abnormalities
what are the levels and signs of lithium toxicity? - CORRECT ANSWERS-mild (1.5-2):
lethargy, tremor, increased GI upset
moderate (2-2.5) confusion, nystagmus
severe (>2.5) convulsions, oliguria, renal failure, seizures