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NUCLEAR MEDICINE BOARD REVIEW
QUESTIONS AND CORRECT DETAILED
ANSWERS |ALREADY GRADED A+
LATEST UPDATE | 2024-2025
Gas Ventilation
✓ Xe 133, 81 KeV, 5.3 half life; reactor produced
✓ dose: 10-20 mCi
✓ imaging: posterior position
✓ negative pressure room required
✓ uses activated charcoal trap to accumulate the exhaled xenon gas until decayed to
background
✓ single breath: during inhalation
✓ wash in / equilibrium : collected while the xenon distributes through aerated portions of
the lung
✓ wash out : while radioactivity is cleared from lungs
Sr 89 Chloride
✓ Strontium Chloride, Metastron
✓ 1.46 MeV max, .58 Mev mean
✓ half life = 50.5 days
✓ 40-60 uci/kg IV
✓ for skeletal mets, depresses bone marrow
✓ shouldn't be used if leukocyte count below 2400/ul or platelet below 60,o00/ul
✓ excretion : urinary
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I 131 Tositumomab
✓ Bexxar
✓ half life = 8.04 days
✓ 606.3 KeV max energy
✓ treatment of patients with NHL
✓ before treatment, patient must receive 650 mg acetaminophen and 50mg diphydramine
orally
✓ thyroid uptake should be minimized with SSKI
✓ activity initially seen in blood pool, liver and spleen
✓ later times, activity in liver, spleen, thyroid, bladder, and tumor sites
Y 90 ibritumomab tiuxtetan
✓ Zevalin
✓ half life = 2.67 days
✓ 2.281 MeV
✓ treatment of patients with NHL (disseminated follicular B-Cell)
✓ monoclonal antibody against lymphoma antigens
✓ before treatment, patient must receive 650 mg (imaging) acetaminophen and 50mg
diphydramine orally
✓ max dose = 32 mci
✓ platelets must be at least 100,000/mm3
Sm 153 EDTMP
|
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✓ ethylenediaminetetra methylene phosphonic
✓ Quadramet
✓ half life = 46.7 hours
✓ 0.81 MeV maximum
✓ concentrates in bone marrow
✓ for patients with more metabolically activate metastases from prostate or breast cancer,
as well as those from osteogenic sarcoma
✓ 1.0mci/kg
✓ urinary excretion
Bone therapy blood requirements
✓ 60,000-100,000/ul platelet
✓ 2400-3000/ul leukocyte
✓ 2000/ul granuolyte
I 131 MIBG
✓ metaiodobenzylguanidine
✓ half life = 8.06 days
✓ localization/treatment of primary or metastatic pheochromocytomas/ neuroblastoma
✓ 8.04 days
✓ kidney/ urinary excretion
I 131 Sodium Iodide
|
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✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
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✓ half life = 8.06 days
✓ used to treat hyperthyroidism, thyroid carcinoma
✓ 10-15 mCi for graves
✓ 20-30 mCi for nodular goiters
✓ *special release precautions
Blood Brain Barrier Imaging
✓ Tc99m Pertechnetate
✓ -least desirable (accumulated in choroid plexus)
✓ -15-30mCi
✓ -premed with KCLO4- preferred
✓ Tc99m Pentetate (DTPA)
✓ -planar
✓ -cleared by kidneys
✓ Dynamic imaging: cerebral blood flow
✓ static blood pool
✓ delayed statics: 3-30 min after
✓ 6 sec after tracer: rt and lt carotid and anterior cerebral
✓ abnormal: increased localization of RP
✓ brain death: tracer distribution in carotids, abscense of perfusion
Brain Perfusion
|
✓ Thank You for Choosing Us! ✓ Resources & Updates: [Testtrackers - Stuvia US]
✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
NUCLEAR MEDICINE BOARD REVIEW
QUESTIONS AND CORRECT DETAILED
ANSWERS |ALREADY GRADED A+
LATEST UPDATE | 2024-2025
Gas Ventilation
✓ Xe 133, 81 KeV, 5.3 half life; reactor produced
✓ dose: 10-20 mCi
✓ imaging: posterior position
✓ negative pressure room required
✓ uses activated charcoal trap to accumulate the exhaled xenon gas until decayed to
background
✓ single breath: during inhalation
✓ wash in / equilibrium : collected while the xenon distributes through aerated portions of
the lung
✓ wash out : while radioactivity is cleared from lungs
Sr 89 Chloride
✓ Strontium Chloride, Metastron
✓ 1.46 MeV max, .58 Mev mean
✓ half life = 50.5 days
✓ 40-60 uci/kg IV
✓ for skeletal mets, depresses bone marrow
✓ shouldn't be used if leukocyte count below 2400/ul or platelet below 60,o00/ul
✓ excretion : urinary
|
✓ Thank You for Choosing Us! ✓ Resources & Updates: [Testtrackers - Stuvia US]
✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
, TestTrackers: Unlock Your Exam Potential! | Quality Practice Materials | Boost Your Confidence Today!
I 131 Tositumomab
✓ Bexxar
✓ half life = 8.04 days
✓ 606.3 KeV max energy
✓ treatment of patients with NHL
✓ before treatment, patient must receive 650 mg acetaminophen and 50mg diphydramine
orally
✓ thyroid uptake should be minimized with SSKI
✓ activity initially seen in blood pool, liver and spleen
✓ later times, activity in liver, spleen, thyroid, bladder, and tumor sites
Y 90 ibritumomab tiuxtetan
✓ Zevalin
✓ half life = 2.67 days
✓ 2.281 MeV
✓ treatment of patients with NHL (disseminated follicular B-Cell)
✓ monoclonal antibody against lymphoma antigens
✓ before treatment, patient must receive 650 mg (imaging) acetaminophen and 50mg
diphydramine orally
✓ max dose = 32 mci
✓ platelets must be at least 100,000/mm3
Sm 153 EDTMP
|
✓ Thank You for Choosing Us! ✓ Resources & Updates: [Testtrackers - Stuvia US]
✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
, TestTrackers: Unlock Your Exam Potential! | Quality Practice Materials | Boost Your Confidence Today!
✓ ethylenediaminetetra methylene phosphonic
✓ Quadramet
✓ half life = 46.7 hours
✓ 0.81 MeV maximum
✓ concentrates in bone marrow
✓ for patients with more metabolically activate metastases from prostate or breast cancer,
as well as those from osteogenic sarcoma
✓ 1.0mci/kg
✓ urinary excretion
Bone therapy blood requirements
✓ 60,000-100,000/ul platelet
✓ 2400-3000/ul leukocyte
✓ 2000/ul granuolyte
I 131 MIBG
✓ metaiodobenzylguanidine
✓ half life = 8.06 days
✓ localization/treatment of primary or metastatic pheochromocytomas/ neuroblastoma
✓ 8.04 days
✓ kidney/ urinary excretion
I 131 Sodium Iodide
|
✓ Thank You for Choosing Us! ✓ Resources & Updates: [Testtrackers - Stuvia US]
✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
, TestTrackers: Unlock Your Exam Potential! | Quality Practice Materials | Boost Your Confidence Today!
✓ half life = 8.06 days
✓ used to treat hyperthyroidism, thyroid carcinoma
✓ 10-15 mCi for graves
✓ 20-30 mCi for nodular goiters
✓ *special release precautions
Blood Brain Barrier Imaging
✓ Tc99m Pertechnetate
✓ -least desirable (accumulated in choroid plexus)
✓ -15-30mCi
✓ -premed with KCLO4- preferred
✓ Tc99m Pentetate (DTPA)
✓ -planar
✓ -cleared by kidneys
✓ Dynamic imaging: cerebral blood flow
✓ static blood pool
✓ delayed statics: 3-30 min after
✓ 6 sec after tracer: rt and lt carotid and anterior cerebral
✓ abnormal: increased localization of RP
✓ brain death: tracer distribution in carotids, abscense of perfusion
Brain Perfusion
|
✓ Thank You for Choosing Us! ✓ Resources & Updates: [Testtrackers - Stuvia US]
✓ © 2024 TestTrackers ✓ Your Success is Our Mission!
✓ Customer Support: [+254707240657]
