, Pharmacotherapeutics for APN Prescribers, 6e s s s s Ch01
Chapter 1. The Role of the Advanced Practice Nurse as Prescriber
s s s s s s s s s s
MULTIPLE CHOICE s
1. Nurse practitioner prescriptive authority is regulated by:
s s s s s s
A. The National Council of State Boards of Nursing
s s s s s s s
B. The U.S. Drug Enforcement Administration
s s s s
C. The State Board of Nursing for each state
s s s s s s s
D. The State Board of Pharmacy
s s s s
ANS: C s PTS: 1 s
2. The benefits to the patient of having an advanced practice registered nurse (APRN) prescriber
s s s s s s s s s s s s s
include:
s
A. Nurses know more about pharmacology than other prescribers because they take it
s s s s s s s s s s s
both in their basic nursing program and in their APRN program.
s s s s s s s s s s s
B. Nurses care for the patient from a holistic approach and include the patient in
s s s s s s s s s s s s s
decision-making regarding their care.
s s s s
C. APRNs are less likely to prescribe narcotics and other controlled substances.
s s s s s s s s s s
D. APRNs are able to prescribe independently in all states, whereas a physician’s
s s s s s s s s s s s
assistant needs to have a physician supervising their practice.
s s s s s s s s s
ANS: B s PTS: 1 s
3. Clinical judgment in prescribing includes:
s s s s
A. Factoring in the cost to the patient of the medication prescribed
s s s s s s s s s s
B. Always prescribing the newest medication available for the disease process
s s s s s s s s s
C. Handing out drug samples to poor patients s s s s s s
D. Prescribing all generic medications to cut costs s s s s s s
ANS: A s PTS: 1 s
4. The process for choosing an effective drug for a disorder includes:
s s s s s s s s s s
A. Asking the patient what drug they think would work best for them
s s s s s s s s s s s
B. Consulting nationally recognized guidelines for disease management
s s s s s s
C. Prescribing medications that are available as samples before writing a prescription
s s s s s s s s s s
D. Following U.S. Drug Enforcement Administration guidelines for prescribing
s s s s s s s
ANS: B s PTS: 1 s
5. Nonintentional nonadherence of drug therapy may occur due to: s s s s s s s s
A. Belief that medication does not work
s s s s s
B. Adverse drug reactions s s
C. Chronic conditions that require daily therapys s s s s
D. Forgetfulness or distraction s s
ANS: D s PTS: 1 s
, Woo 1
Pharmacotherapeutics for APN Prescribers, 6e s s s s Ch02
Chapter 2. Review of Basic Principles of Pharmacology
s s s s s s s
MULTIPLE CHOICE s
1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical
s s s s s s s s s s s
to prescribing because:
s s s
A. Distribution of drugs to target tissue may be affected. s s s s s s s s
B. The solubility of the drug will not match the site of absorption.
s s s s s s s s s s s
C. There will be less free drug available to generate an effect.
s s s s s s s s s s
D. Drugs bound to albumin are readily excreted by the kidneys.
s s s s s s s s s
ANS: A s PTS: 1 s
2. Drugs that have a significant first-pass effect:
s s s s s s
A. Must be given by the enteral (oral) route only
s s s s s s s s
B. Bypass the hepatic circulation s s s
C. Are rapidly metabolized by the liver and may have little, if any, desired action
s s s s s s s s s s s s s
D. Are converted by the liver to more active and fat-soluble forms
s s s s s s s s s s
ANS: C s PTS: 1 s
3. The route of excretion of a volatile drug will likely be the:
s s s s s s s s s s s
A. Kidneys
B. Lungs
C. Bile and feces s s
D. Skin
ANS: B s PTS: 1 s
4. A major disadvantage to IV administration is that:
s s s s s s s
A. First-pass metabolism is eliminated. s s s
B. Needles and sterility are required. s s s s
C. Absorption of the drug cannot be slowed after administration. s s s s s s s s
D. It is significantly more expensive than other routes.
s s s s s s s
ANS: C s PTS: 1 ss s
5. The nurse practitioner (NP) chooses to give cephalexin every 8 hours based on knowledge of
s s s s s s s s s s s s s s
the drug’s:
s s
A. Propensity to go to the target receptor s s s s s s
B. Biological half-life s
C. Pharmacodynamics
D. Safety and side effects s s s
ANS: B s PTS: 1 s
6. Deferasirox is a chelating agent used to treat iron overload by binding iron to render it
s s s s s s s s s s s s s s s
biologically inactive. This is best characterized as a(n):
s s s s s s s s
, Woo 2
Pharmacotherapeutics for APN Prescribers, 6e s s s s Ch02
A. Nonreceptor mechanism s
B. Partial agonist s
C. Full agonist s
D. Noncompetitive antagonist s
ANS: A s PTS: 1 s
7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic
s s s s s s s s s s s s s s s s
effect is the:
s s s
A. Minimum adverse effect level s s s
B. Peak of action s s
C. Onset of action s s
D. Therapeutic range s
ANS: C s PTS: 1 s
8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
s s s s s s s s s s s s s
A. When the drug has a wide therapeutic range
s s s s s s s
B. When the drug will be administered for a short time only
s s s s s s s s s s
C. When there is a high correlation between the dose and saturation of receptor sites
s s s s s s s s s s s s s
D. To determine if a drug is in the therapeutic range
s s s s s s s s s
ANS: D s PTS: 1 s
9. A laboratory result indicates that the peak level for a drug is above the minimum toxic
s s s s s s s s s s s s s s s
concentration. This means that the:
s s s s s
A. Concentration will produce therapeutic effects. s s s s
B. Concentration will produce an adverse response. s s s s s
C. Time between doses must be shortened.
s s s s s
D. Duration of action of the drug is too long. s s s s s s s s
ANS: B s PTS: 1 s
10. Drugs that are receptor agonists may demonstrate what property?
s s s s s s s s
A. Irreversible binding to the drug receptor site s s s s s s
B. Up-regulation with chronic use s s s
C. Desensitization or down-regulation with continuous use s s s s s
D. Inverse relationship between drug concentration and drug action
s s s s s s s
ANS: C s PTS: 1 s
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
s s s s s s s s s s
A. Down-regulation of the drug receptor s s s s
B. An exaggerated response if abruptly discontinued
s s s s s
C. Partial blockade of the effects of agonist drugs
s s s s s s s
D. An exaggerated response to competitive drug agonists
s s s s s s
ANS: B s PTS: 1 s
Chapter 1. The Role of the Advanced Practice Nurse as Prescriber
s s s s s s s s s s
MULTIPLE CHOICE s
1. Nurse practitioner prescriptive authority is regulated by:
s s s s s s
A. The National Council of State Boards of Nursing
s s s s s s s
B. The U.S. Drug Enforcement Administration
s s s s
C. The State Board of Nursing for each state
s s s s s s s
D. The State Board of Pharmacy
s s s s
ANS: C s PTS: 1 s
2. The benefits to the patient of having an advanced practice registered nurse (APRN) prescriber
s s s s s s s s s s s s s
include:
s
A. Nurses know more about pharmacology than other prescribers because they take it
s s s s s s s s s s s
both in their basic nursing program and in their APRN program.
s s s s s s s s s s s
B. Nurses care for the patient from a holistic approach and include the patient in
s s s s s s s s s s s s s
decision-making regarding their care.
s s s s
C. APRNs are less likely to prescribe narcotics and other controlled substances.
s s s s s s s s s s
D. APRNs are able to prescribe independently in all states, whereas a physician’s
s s s s s s s s s s s
assistant needs to have a physician supervising their practice.
s s s s s s s s s
ANS: B s PTS: 1 s
3. Clinical judgment in prescribing includes:
s s s s
A. Factoring in the cost to the patient of the medication prescribed
s s s s s s s s s s
B. Always prescribing the newest medication available for the disease process
s s s s s s s s s
C. Handing out drug samples to poor patients s s s s s s
D. Prescribing all generic medications to cut costs s s s s s s
ANS: A s PTS: 1 s
4. The process for choosing an effective drug for a disorder includes:
s s s s s s s s s s
A. Asking the patient what drug they think would work best for them
s s s s s s s s s s s
B. Consulting nationally recognized guidelines for disease management
s s s s s s
C. Prescribing medications that are available as samples before writing a prescription
s s s s s s s s s s
D. Following U.S. Drug Enforcement Administration guidelines for prescribing
s s s s s s s
ANS: B s PTS: 1 s
5. Nonintentional nonadherence of drug therapy may occur due to: s s s s s s s s
A. Belief that medication does not work
s s s s s
B. Adverse drug reactions s s
C. Chronic conditions that require daily therapys s s s s
D. Forgetfulness or distraction s s
ANS: D s PTS: 1 s
, Woo 1
Pharmacotherapeutics for APN Prescribers, 6e s s s s Ch02
Chapter 2. Review of Basic Principles of Pharmacology
s s s s s s s
MULTIPLE CHOICE s
1. A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical
s s s s s s s s s s s
to prescribing because:
s s s
A. Distribution of drugs to target tissue may be affected. s s s s s s s s
B. The solubility of the drug will not match the site of absorption.
s s s s s s s s s s s
C. There will be less free drug available to generate an effect.
s s s s s s s s s s
D. Drugs bound to albumin are readily excreted by the kidneys.
s s s s s s s s s
ANS: A s PTS: 1 s
2. Drugs that have a significant first-pass effect:
s s s s s s
A. Must be given by the enteral (oral) route only
s s s s s s s s
B. Bypass the hepatic circulation s s s
C. Are rapidly metabolized by the liver and may have little, if any, desired action
s s s s s s s s s s s s s
D. Are converted by the liver to more active and fat-soluble forms
s s s s s s s s s s
ANS: C s PTS: 1 s
3. The route of excretion of a volatile drug will likely be the:
s s s s s s s s s s s
A. Kidneys
B. Lungs
C. Bile and feces s s
D. Skin
ANS: B s PTS: 1 s
4. A major disadvantage to IV administration is that:
s s s s s s s
A. First-pass metabolism is eliminated. s s s
B. Needles and sterility are required. s s s s
C. Absorption of the drug cannot be slowed after administration. s s s s s s s s
D. It is significantly more expensive than other routes.
s s s s s s s
ANS: C s PTS: 1 ss s
5. The nurse practitioner (NP) chooses to give cephalexin every 8 hours based on knowledge of
s s s s s s s s s s s s s s
the drug’s:
s s
A. Propensity to go to the target receptor s s s s s s
B. Biological half-life s
C. Pharmacodynamics
D. Safety and side effects s s s
ANS: B s PTS: 1 s
6. Deferasirox is a chelating agent used to treat iron overload by binding iron to render it
s s s s s s s s s s s s s s s
biologically inactive. This is best characterized as a(n):
s s s s s s s s
, Woo 2
Pharmacotherapeutics for APN Prescribers, 6e s s s s Ch02
A. Nonreceptor mechanism s
B. Partial agonist s
C. Full agonist s
D. Noncompetitive antagonist s
ANS: A s PTS: 1 s
7. The point in time on the drug concentration curve that indicates the first sign of a therapeutic
s s s s s s s s s s s s s s s s
effect is the:
s s s
A. Minimum adverse effect level s s s
B. Peak of action s s
C. Onset of action s s
D. Therapeutic range s
ANS: C s PTS: 1 s
8. Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
s s s s s s s s s s s s s
A. When the drug has a wide therapeutic range
s s s s s s s
B. When the drug will be administered for a short time only
s s s s s s s s s s
C. When there is a high correlation between the dose and saturation of receptor sites
s s s s s s s s s s s s s
D. To determine if a drug is in the therapeutic range
s s s s s s s s s
ANS: D s PTS: 1 s
9. A laboratory result indicates that the peak level for a drug is above the minimum toxic
s s s s s s s s s s s s s s s
concentration. This means that the:
s s s s s
A. Concentration will produce therapeutic effects. s s s s
B. Concentration will produce an adverse response. s s s s s
C. Time between doses must be shortened.
s s s s s
D. Duration of action of the drug is too long. s s s s s s s s
ANS: B s PTS: 1 s
10. Drugs that are receptor agonists may demonstrate what property?
s s s s s s s s
A. Irreversible binding to the drug receptor site s s s s s s
B. Up-regulation with chronic use s s s
C. Desensitization or down-regulation with continuous use s s s s s
D. Inverse relationship between drug concentration and drug action
s s s s s s s
ANS: C s PTS: 1 s
11. Drugs that are receptor antagonists, such as beta blockers, may cause:
s s s s s s s s s s
A. Down-regulation of the drug receptor s s s s
B. An exaggerated response if abruptly discontinued
s s s s s
C. Partial blockade of the effects of agonist drugs
s s s s s s s
D. An exaggerated response to competitive drug agonists
s s s s s s
ANS: B s PTS: 1 s
