advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
What is BEERS criteria? Answer✓✓
Recommendations of medications inappropriate for the elderly (65 and older), the
prescriber ultimately decides
What is the CYP450 (cytochrome P450)
liver enzyme system where medications are metabolized, can either be inducers or
inhibitors and create drug-drug interactions
CYP450 inducers
Speed up metabolism of drugs (drug is cleared faster), drug has lesser effect
(decrease blood levels of drug), elevate CYP450 enzymes
CYP450 inducers pneumonic
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,NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
CYP450 inducer drug names
Barbituates, St John wort, Carbamazepine, rifampin, alcohol, phenytoin, griseofulvin,
phenobarbital, sulfonylureas
CYP450 inhibitors
inhibit metabolism, increase blood levels of medications
CYP450 pneumonic
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CYP450 inhibitors drug names
Valproate, isoniazid, sulfonamides, amiodarone, chloramphenicol, ketoconazole,
grapefruit juice, quinidine
,NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
Physiological changes during pregnancy that impact pharmacodynamics and
pharmacokinetic properties of drugs? Answer✓✓
increase glomerular filtration rate leads to increased drug excretion
increase hepatic metabolism
decrease tone and motility of the bowel
increase drug absorption
Examples of medications that can be teratogenic
Antiepileptic drugs, antimicrobials such as tetracyclines and fluoroquinolones,
vitamin A in large doses, some anticoagulants, and hormonal medications such as
diethylstilbestrol (DES).
How is absorption of intramuscular medications different in neonates? Answer✓✓
slow and erratic due to low blood flow in muscles first few days of life
Why is absorption of medication in the stomach increased in infancy? Answer✓✓
delayed gastric emptying
, NR565/NR 565 -
advanced pharmacology
care of the fundamentals
real midterm Exam
verified & graded A+|
2024 Updated
Some medications that should be avoided in the pediatric patient? Answer✓✓
glucocorticoids, discoloration of developing teeth with tetracyclines, and kernicterus
with sulfonamides, levofloxacin (antibiotics)
aspirin (Severe intoxication from acute overdose)
what should be included in medication administration patient education? Answer✓✓
dosage size and timing
route and technique of administration
duration of treatment
drug storage
nature and time course of desired responses
nature and time course of adverse responses
finish taking antibiotic