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CSB520 (Week 7) Exam Study Guide.

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©BRIGHTSTARS EXAM SOLUTIONS 11/16/2024 10:16 AM 1 | P a g e CSB520 (Week 7) Exam Study Guide. Define horseshoe kidney Define polycystic kidney disease What is the likelihood of being a carrier of adult polycystic kidney disease if one of your parents has the disease? - answer- adult polycystic kidney disease is autosomal dominant and if you inherit one disease allele you will have the disease (you cannot be a carrier of the disease) - childhood polycystic kidney disease is autosomal recessive What has happened to the normal renal parenchyma in response to the formation and growth of the cysts (following adult polycystic kidney disease)? - answer- formation and growth of cysts - atrophy - parenchymal cells of kidney die by apoptosis (and only cysts persist) What are the differences between acute and chronic renal failure? - answerACUTE (ARF) - hours-days - pre-renal - renal - post-renal CHRONIC (CKD) - weeks-months-years What are common causes of chronic renal failure? - answer- hypertension - diabetes - heart disease ©BRIGHTSTARS EXAM SOLUTIONS 11/16/2024 10:16 AM 2 | P a g e - obesity - smoking - age ( 60) - aboriginal or torres strait islander origin - family history of CKD - personal history of ARF What are the symptoms of chronic renal failure? - answer- azotaemia/uraemia (increased urine) - hypertension - oedema - acidosis - hyperkalaemia (increased potassium) - hyperphosphatemia (increased phosphate) - anaemia What is the role of the kidneys (RENAL PHYSIOLOGY)? - answer- form urine (or remove waste) - regulate plasma ions - regulate pH - activate vitamin D, RAAS and EPO (endocrine function) - regulate blood volume - regulate blood pressure - detoxify drugs/toxins (metabolism function) What impact does chronic renal failure have on the rest of the body? - answer(1) excessive activation of RAAS - increased blood pressure - hypertension - atherosclerosis

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©BRIGHTSTARS EXAM SOLUTIONS

11/16/2024 10:16 AM



CSB520 (Week 7) Exam Study Guide.

Define horseshoe kidney
Define polycystic kidney disease
What is the likelihood of being a carrier of adult polycystic kidney disease if one of your parents
has the disease? - answer✔- adult polycystic kidney disease is autosomal dominant and if you
inherit one disease allele you will have the disease (you cannot be a carrier of the disease)
- childhood polycystic kidney disease is autosomal recessive
What has happened to the normal renal parenchyma in response to the formation and growth
of the cysts (following adult polycystic kidney disease)? - answer✔- formation and growth of
cysts
- atrophy
- parenchymal cells of kidney die by apoptosis (and only cysts persist)

What are the differences between acute and chronic renal failure? - answer✔ACUTE (ARF)
- hours-days
- pre-renal
- renal
- post-renal


CHRONIC (CKD)
- weeks-months-years

What are common causes of chronic renal failure? - answer✔- hypertension
- diabetes
- heart disease


1|Page

, ©BRIGHTSTARS EXAM SOLUTIONS

11/16/2024 10:16 AM

- obesity
- smoking
- age (> 60)
- aboriginal or torres strait islander origin
- family history of CKD
- personal history of ARF

What are the symptoms of chronic renal failure? - answer✔- azotaemia/uraemia (increased
urine)
- hypertension
- oedema
- acidosis
- hyperkalaemia (increased potassium)
- hyperphosphatemia (increased phosphate)
- anaemia

What is the role of the kidneys (RENAL PHYSIOLOGY)? - answer✔- form urine (or remove waste)
- regulate plasma ions
- regulate pH
- activate vitamin D, RAAS and EPO (endocrine function)
- regulate blood volume
- regulate blood pressure
- detoxify drugs/toxins (metabolism function)

What impact does chronic renal failure have on the rest of the body? - answer✔(1) excessive
activation of RAAS
- increased blood pressure
- hypertension
- atherosclerosis

2|Page

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