©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
CMB 352 Exam #3 Questions With Correct
Answers
Which of the following statements correctly describes telomerase?
a) Telomerase carries its own DNA template
b) Inactivation of telomerase contributes to the extended lifespan of cancer cells
c) Telomerase extends the 3'-ends of the lagging strand template of linear chromosomes
d) Telomerase separates the circular daughter strands in E. coli DNA replication
e) Telomerase unwinds the DNA in the pre-priming stage of DNA replication - answer✔c)
Telomerase extends the 3'-ends of the lagging strand template of linear chromosomes
In prokaryotic transcription, the role of the sigma factor is...
a) to catalyze the formation of phosphodiester bonds
b) to position RNA polymerase at a transcription start site
c) to release the completed transcript from the template DNA
d) to separate DNA strands during elongation
e) to terminate transcription at specific secondary structures - answer✔b) to position RNA
polymerase at a transcription start site
A fundamental difference between DNA polymerase I (Kornberg enzyme) and DNA polymerase
III is...
a) Pol I has a single catalytic site for DNA synthesis while Pol III has three catalytic sites for DNA
synthesis
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, ©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
b) Pol I consists of multiple polypeptide subunits while Pol III consists of a single subunit
c) Pol I can synthesize both DNA and RNA while Pol III can only synthesis DNA
d) Pol I has a low processivity and Pol III has high processivity
e) All of the above are true - answer✔d) Pol I have low processivity and III has high processivity
During elongation of protein synthesis the charged tRNA is always added at the...
a) A site of the ribosome
b) P site of the ribosome
c) active site of the tRNA-aminoacyl synthetase
d) to the Shine-Dalgarno sequence
e) to the polyA tail of the mRNA transcript - answer✔a) A site of the ribosome
Which DNA polymerase is mainly responsible for genome replication in eukaryotic cells?
a) DNA polymerase a (alpha)
b) DNA polymerase I
c) DNA polymerase II
d) DNA polymerase III
e) DNA polymerase d (delta) - answer✔e) DNA polymerase d (delta)
If the GC content of a DNA molecule is 60%, what are the percentages of the four bases (G, C, T,
A)?
a) G = 60%, C = 60%, A = 40%, T = 40%
b) G = 30%, C = 30%, A = 20%, T = 20%
c) G = 30%, A = 30%, C = 20%, T = 20%
d) G = 60%, C = 60%, A = 40%, U = 40%
e) G = 30%, C = 30%, A = 20%, U = 20% - answer✔b) G = 30%, C = 30%, A = 20%, T = 20%
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11/16/2024 10:16 AM
CMB 352 Exam #3 Questions With Correct
Answers
Which of the following statements correctly describes telomerase?
a) Telomerase carries its own DNA template
b) Inactivation of telomerase contributes to the extended lifespan of cancer cells
c) Telomerase extends the 3'-ends of the lagging strand template of linear chromosomes
d) Telomerase separates the circular daughter strands in E. coli DNA replication
e) Telomerase unwinds the DNA in the pre-priming stage of DNA replication - answer✔c)
Telomerase extends the 3'-ends of the lagging strand template of linear chromosomes
In prokaryotic transcription, the role of the sigma factor is...
a) to catalyze the formation of phosphodiester bonds
b) to position RNA polymerase at a transcription start site
c) to release the completed transcript from the template DNA
d) to separate DNA strands during elongation
e) to terminate transcription at specific secondary structures - answer✔b) to position RNA
polymerase at a transcription start site
A fundamental difference between DNA polymerase I (Kornberg enzyme) and DNA polymerase
III is...
a) Pol I has a single catalytic site for DNA synthesis while Pol III has three catalytic sites for DNA
synthesis
1|Page
, ©BRIGHTSTARS EXAM SOLUTIONS
11/16/2024 10:16 AM
b) Pol I consists of multiple polypeptide subunits while Pol III consists of a single subunit
c) Pol I can synthesize both DNA and RNA while Pol III can only synthesis DNA
d) Pol I has a low processivity and Pol III has high processivity
e) All of the above are true - answer✔d) Pol I have low processivity and III has high processivity
During elongation of protein synthesis the charged tRNA is always added at the...
a) A site of the ribosome
b) P site of the ribosome
c) active site of the tRNA-aminoacyl synthetase
d) to the Shine-Dalgarno sequence
e) to the polyA tail of the mRNA transcript - answer✔a) A site of the ribosome
Which DNA polymerase is mainly responsible for genome replication in eukaryotic cells?
a) DNA polymerase a (alpha)
b) DNA polymerase I
c) DNA polymerase II
d) DNA polymerase III
e) DNA polymerase d (delta) - answer✔e) DNA polymerase d (delta)
If the GC content of a DNA molecule is 60%, what are the percentages of the four bases (G, C, T,
A)?
a) G = 60%, C = 60%, A = 40%, T = 40%
b) G = 30%, C = 30%, A = 20%, T = 20%
c) G = 30%, A = 30%, C = 20%, T = 20%
d) G = 60%, C = 60%, A = 40%, U = 40%
e) G = 30%, C = 30%, A = 20%, U = 20% - answer✔b) G = 30%, C = 30%, A = 20%, T = 20%
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