ZOO 3603C - Exam 1 Sample Questions
Study online at https://quizlet.com/_f1vw5t
1. How has developmental biolo- IVF (in vitro fertilization)
gy impacted modern medicine? teratology - study of congenital abnormal-
ities
Birth defects, prenatal diagnosis
cloning
2. What is regulation? the ability to respecify cells so that the
removal of cells destined to become a
particular structure can be compensated
for by other cells producing that structure
3. Who discovered Regulation? Roux
4. What is determination? the second and irreversible stage of a cell
or tissue commitment in which the cell
or tissue is capable of differentiating au-
tonomously, even when placed in a non
neutral environment
5. What "proved" determination Weisman and Conklin
Experimented with snail eggs and found
that the germ layers were determined be-
cause macho-1 was only found in early
mesodermal cells and could not be re-
versed
Shown to only be true in certain organ-
isms
6. What enables us to be able to Human embryo is regulative. Therefore,
do IVF and prenatal diagnosis? you can take one of the eight human blas-
tula cells and it is not detrimental to devel-
opment.
7. What did Hartsoeker believe He was a preformationist. He looked at his
about development? sperm through a lens and believed that a
tiny man was sitting in the acrosome. The
yolk allows the fetus to grow
8. What did Driesh believe? Entelechy
A vital force drives development
, ZOO 3603C - Exam 1 Sample Questions
Study online at https://quizlet.com/_f1vw5t
9. What did Child believe? Metabolic gradients determined the differ-
ent embryonic laters
No molecular bio to back it up though
10. Who discovered the organizer Spemann discovered the organizer by
and how? grafting it to the other side of a xenopus
embryo
-Wolpart also proposed the organizer!
11. What are examples of the orga- Dorsal lip of the blastopore (xenopus)
nizer? Zone of Polarizing Activity (organizer in
chick limb bud)
Notochord (organizes DV axis in spinal
chord)
12. How do the organizers work? Cells interpret what to do based on their
position in a field. Position determined by
concentration of morphogen.
13. What is "in situ" hybridization? A technique used to localize mRNA
Show's how morphogens are produced in
a gradient and diffuse
14. What are common mor- Shh
phogens? FGFs
Wnts
BMP (activin)
Nodal
RA - retinoic acid
15. What stops the morphogen Antagonists switch the signal off
from diffusing across an entire
embryo?
16. What commits the germ cells to cytoplasmic determinants (germ
their fate early? plasm/mRNA)
17. C. elegans - polar granules
Drosophila - pole plasm
Study online at https://quizlet.com/_f1vw5t
1. How has developmental biolo- IVF (in vitro fertilization)
gy impacted modern medicine? teratology - study of congenital abnormal-
ities
Birth defects, prenatal diagnosis
cloning
2. What is regulation? the ability to respecify cells so that the
removal of cells destined to become a
particular structure can be compensated
for by other cells producing that structure
3. Who discovered Regulation? Roux
4. What is determination? the second and irreversible stage of a cell
or tissue commitment in which the cell
or tissue is capable of differentiating au-
tonomously, even when placed in a non
neutral environment
5. What "proved" determination Weisman and Conklin
Experimented with snail eggs and found
that the germ layers were determined be-
cause macho-1 was only found in early
mesodermal cells and could not be re-
versed
Shown to only be true in certain organ-
isms
6. What enables us to be able to Human embryo is regulative. Therefore,
do IVF and prenatal diagnosis? you can take one of the eight human blas-
tula cells and it is not detrimental to devel-
opment.
7. What did Hartsoeker believe He was a preformationist. He looked at his
about development? sperm through a lens and believed that a
tiny man was sitting in the acrosome. The
yolk allows the fetus to grow
8. What did Driesh believe? Entelechy
A vital force drives development
, ZOO 3603C - Exam 1 Sample Questions
Study online at https://quizlet.com/_f1vw5t
9. What did Child believe? Metabolic gradients determined the differ-
ent embryonic laters
No molecular bio to back it up though
10. Who discovered the organizer Spemann discovered the organizer by
and how? grafting it to the other side of a xenopus
embryo
-Wolpart also proposed the organizer!
11. What are examples of the orga- Dorsal lip of the blastopore (xenopus)
nizer? Zone of Polarizing Activity (organizer in
chick limb bud)
Notochord (organizes DV axis in spinal
chord)
12. How do the organizers work? Cells interpret what to do based on their
position in a field. Position determined by
concentration of morphogen.
13. What is "in situ" hybridization? A technique used to localize mRNA
Show's how morphogens are produced in
a gradient and diffuse
14. What are common mor- Shh
phogens? FGFs
Wnts
BMP (activin)
Nodal
RA - retinoic acid
15. What stops the morphogen Antagonists switch the signal off
from diffusing across an entire
embryo?
16. What commits the germ cells to cytoplasmic determinants (germ
their fate early? plasm/mRNA)
17. C. elegans - polar granules
Drosophila - pole plasm
