GEORGETTE MODULE 3 EXAM WITH
ALL NEEDED TO PASS
What his ha hdecreased heffect hof hthe hsame hdose hof ha hmedication hovertime? h-
hTolerance
Ex. htaking h2 hpills hof hibuprofen hover ha hperiod hof htime hso hnow hneeding hto
htake h3 hpills hto hachieve hthe hsame heffect
What his hit hcalled hwhen hthere his ha htendency hof hsome hregions hof hthe hbrain
hto hreact hto hrepeated hLOW hlevel hbioelectrical hstimulation hby hprogressively
hboosting hsynaptic hdischarges hthereby hlowering hseizure hthresholds? h- hKindling
Kindling hexplanation/definition h- hprocess hof hneuronal hmembrane hthreshold
hsensitivity hdysfunction
-d/t hsubthreshold hbrain hstimulation
-brain's hoverly hsensitive hto helectrical hstimuli
-neuronal hmisfiring h(occurs hw/o hstimuli)
,3 htypes hof hADHD h- hInattention
Hyperactivity/impulsivity
Combined htype
Dx hcriteria hfor hADHD h(all h3 htypes) h- h-Hyperactivity h& hInattentive htype= h6 hfor
hchildren, h5 hfor hadults
-Combined htype h(6 hin heach harea)
-6 hMONTHS
-BEFORE hAGE h12
-2 hSETTINGS
Inattentive hADHD hcriteria hsymptoms h- h1. hLack hof hattention hto hdetail
2. hDif. hsustaining hattention
3. hNo hlisten hwhen hspoken hto hdirectly
4. hDoesn't hfollow hthrough hon hinstruction
5. hDif. horganizing htasks/activities
6. hAvoids hsustained hmental heffort
7. hLoses hthings
8. hEasily hdistracted
9. hForgetful
Hyperactivity hADHD hCriteria hsymptoms h- h1. hFidgets/squirms hin hseat
2. hLeaves hseat hfrequently
3. hRestless/run hor hclimbs hwhere hinappropriate
4. hCan't hengage hin hleisure hactivities hQUIETLY
5. hAlways h"on hthe hgo"
6. hTalks hexcessively
7. hBlurts hout hanswer hbefore hquestion hcompleted
8. hDifficulty hwaiting hturn
9. hInterrupts hothers
Brain hAbnormalities hEtiology hof hADHD h- habnormalities hin hfronto-subcortical
hpathway haka hthe hFrontal hcortex, hBasal hGanglia, hRAS
Basal hGanglia hfunction h- h-Motor hcontrol/learning
-Executive hfunction
-Emotions
RAS h(reticular hactivating hsystem) h- hregulates harousal hand hsleep-wake
htransitions, hability hto hfocus, hfight-flight hreponse
what hneurotransmitter habnormalities hare hseen hin hADHD?? h- hNeurotransmitters=
h**DNS**(DA, hNE, h5HT)**
, Stimulants hfor hADHD hinclude hand hwhat hages hare hthey happroved hfor?? h-
hAdderall h(3 hand hup)
Methylphenidate h(6 hand hup)
What hshould hyou hassess hprior hto hgiving ha hstimulant hfor hADHD? hwhy?? h-
hcardiac hhx hbecause hthey hcan hcause helevated hHR h& hBP, hincrease hrisk hof
hMI/CVA/Aneurysm hrupture
Amphetamines hare happroved hfor hwhat hage?? h- h***age h3 hand holder***
Methylphenidate his happroved hfor hwhat hage?? h- h**age h6 hand holder**
Non-stimulants hfor hADHD hinclude h- h1. hAlpha-agonists/Alpha2 hadrenergic
hagonists= h**Clonidine h& hGuanfacine** h(approved hages h6-17 hw/ hADHD)
2. hStraterra h(atomoxetine) happroved hfor h>/= h6yr
Alpha-agonists hFDA happroved hfor hADHD hand hat hwhat hage h- hGuanfacine h&
hClonidine h
ages h6-17 hwith hconfirmed hdx
Straterra h(Atomoxetine) his happroved hfor hwhat hage hin hADHD h- h>/= h6 hyears
hwith hADHD
***know** hthat hfor hchildren h<6 hyears hold, hwhat hto hgive hfor hADHD h- hAdderall
**Know** hwhat hto hgive hwhen hchildren hturn h6 hfor hADHD h- hMethylphenidate
DNS hstands hfor hand hwhat his hit?? h- hDA, hNE, h5HT
(abnormalities hin hADHD hand hsome hothers)
If hchoosing hbetween hGuanfacine h& hClonidine hfor hADHD, hwhich hshould hyou
hchoose hon hthe htest?? hwhy? h- hGuanfacine, hlasts hlonger h& his hless hsedating
Signs hof hstimulant habuse?? h- h**Insomnia
**Tremors
**Increase hin hBP h& hHR
**Heart hPalpitations
Agitation/Anxiety/Irritability/Mood hswings/Elevated hmood
Nonpharmacological hmanagement hfor hADHD hincludes... h- h-Behavioral htherapy
-Pt h& hParent hCBT hprogram
-Psychoeducation
-Tx hof hlearning hd/o
-Family htherapy/edu.
ALL NEEDED TO PASS
What his ha hdecreased heffect hof hthe hsame hdose hof ha hmedication hovertime? h-
hTolerance
Ex. htaking h2 hpills hof hibuprofen hover ha hperiod hof htime hso hnow hneeding hto
htake h3 hpills hto hachieve hthe hsame heffect
What his hit hcalled hwhen hthere his ha htendency hof hsome hregions hof hthe hbrain
hto hreact hto hrepeated hLOW hlevel hbioelectrical hstimulation hby hprogressively
hboosting hsynaptic hdischarges hthereby hlowering hseizure hthresholds? h- hKindling
Kindling hexplanation/definition h- hprocess hof hneuronal hmembrane hthreshold
hsensitivity hdysfunction
-d/t hsubthreshold hbrain hstimulation
-brain's hoverly hsensitive hto helectrical hstimuli
-neuronal hmisfiring h(occurs hw/o hstimuli)
,3 htypes hof hADHD h- hInattention
Hyperactivity/impulsivity
Combined htype
Dx hcriteria hfor hADHD h(all h3 htypes) h- h-Hyperactivity h& hInattentive htype= h6 hfor
hchildren, h5 hfor hadults
-Combined htype h(6 hin heach harea)
-6 hMONTHS
-BEFORE hAGE h12
-2 hSETTINGS
Inattentive hADHD hcriteria hsymptoms h- h1. hLack hof hattention hto hdetail
2. hDif. hsustaining hattention
3. hNo hlisten hwhen hspoken hto hdirectly
4. hDoesn't hfollow hthrough hon hinstruction
5. hDif. horganizing htasks/activities
6. hAvoids hsustained hmental heffort
7. hLoses hthings
8. hEasily hdistracted
9. hForgetful
Hyperactivity hADHD hCriteria hsymptoms h- h1. hFidgets/squirms hin hseat
2. hLeaves hseat hfrequently
3. hRestless/run hor hclimbs hwhere hinappropriate
4. hCan't hengage hin hleisure hactivities hQUIETLY
5. hAlways h"on hthe hgo"
6. hTalks hexcessively
7. hBlurts hout hanswer hbefore hquestion hcompleted
8. hDifficulty hwaiting hturn
9. hInterrupts hothers
Brain hAbnormalities hEtiology hof hADHD h- habnormalities hin hfronto-subcortical
hpathway haka hthe hFrontal hcortex, hBasal hGanglia, hRAS
Basal hGanglia hfunction h- h-Motor hcontrol/learning
-Executive hfunction
-Emotions
RAS h(reticular hactivating hsystem) h- hregulates harousal hand hsleep-wake
htransitions, hability hto hfocus, hfight-flight hreponse
what hneurotransmitter habnormalities hare hseen hin hADHD?? h- hNeurotransmitters=
h**DNS**(DA, hNE, h5HT)**
, Stimulants hfor hADHD hinclude hand hwhat hages hare hthey happroved hfor?? h-
hAdderall h(3 hand hup)
Methylphenidate h(6 hand hup)
What hshould hyou hassess hprior hto hgiving ha hstimulant hfor hADHD? hwhy?? h-
hcardiac hhx hbecause hthey hcan hcause helevated hHR h& hBP, hincrease hrisk hof
hMI/CVA/Aneurysm hrupture
Amphetamines hare happroved hfor hwhat hage?? h- h***age h3 hand holder***
Methylphenidate his happroved hfor hwhat hage?? h- h**age h6 hand holder**
Non-stimulants hfor hADHD hinclude h- h1. hAlpha-agonists/Alpha2 hadrenergic
hagonists= h**Clonidine h& hGuanfacine** h(approved hages h6-17 hw/ hADHD)
2. hStraterra h(atomoxetine) happroved hfor h>/= h6yr
Alpha-agonists hFDA happroved hfor hADHD hand hat hwhat hage h- hGuanfacine h&
hClonidine h
ages h6-17 hwith hconfirmed hdx
Straterra h(Atomoxetine) his happroved hfor hwhat hage hin hADHD h- h>/= h6 hyears
hwith hADHD
***know** hthat hfor hchildren h<6 hyears hold, hwhat hto hgive hfor hADHD h- hAdderall
**Know** hwhat hto hgive hwhen hchildren hturn h6 hfor hADHD h- hMethylphenidate
DNS hstands hfor hand hwhat his hit?? h- hDA, hNE, h5HT
(abnormalities hin hADHD hand hsome hothers)
If hchoosing hbetween hGuanfacine h& hClonidine hfor hADHD, hwhich hshould hyou
hchoose hon hthe htest?? hwhy? h- hGuanfacine, hlasts hlonger h& his hless hsedating
Signs hof hstimulant habuse?? h- h**Insomnia
**Tremors
**Increase hin hBP h& hHR
**Heart hPalpitations
Agitation/Anxiety/Irritability/Mood hswings/Elevated hmood
Nonpharmacological hmanagement hfor hADHD hincludes... h- h-Behavioral htherapy
-Pt h& hParent hCBT hprogram
-Psychoeducation
-Tx hof hlearning hd/o
-Family htherapy/edu.