MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
1. Chronic health effect Problems that de-
velop over a rela-
tively long period
of time, following
either one signifi-
cant exposure that
initiates a prob-
lem, or following a
series of small ex-
posures which ac-
cumulate in some
manner and result
in a development
of a disease or dis-
order
2. acute toxicity Poisoning from a
single dose over a
much shorter du-
ration of time
3. How soon do health effects occur from accrue toxic- Within 24 hours of
ity? exposure
4. Chronic health risk problems (major examples) Mutagenicity,
oncogenicity,
carcinogenicity,
teratogenicity,
neurotoxicity
5. Mutagenicity Ability of a sub-
stance or agent
to cause muta-
tions to genes or
chromosomes
6. Changes from mutagenicity are... Almost always
harmful
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
7. Tests to detect mutagenicity Varied. Tests on
cells to tests on
whole animals
8. It's believed that chemicals that cause mutations are Cancers
more likely to be ones that can also cause...
9. Why is mutation testing used as a first screen for new Faster and cheap-
compounds? er than animal life-
time testing
10. Oncogenicity The ability of a
chemical to cause
abnormal growths
or tumors in tis-
sues
11. Carcinogenicity Ability of a sub-
stance or agent
to cause malig-
nant tumors
12. How do they test chemicals for their ability to cause Administering dai-
tumors ly doses to ani-
mals for their en-
tire lifetime and
then dissecting
them to detect
presence of tu-
mors in the ani-
mals tissues
13. A rodent carcinogenicity study takes how long typi- 2-3 years
cally?
14. Pesticide companies are required to submit test data Several animal
on oncogenicity from.... species
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
15. There are currently how many pesticide active ingre- Over 70
dients considered known, likely, or probable carcino-
gens
16. MDAR Massachusetts
Department of
Agricultural
Resources
17. Act to protect children and families from harmful pes- Passed in 2000.
ticides Pesticide products
that contain car-
cinogens may not
be used in or
around schools,
daycares, or after
school programs
18. Teratogenicity Ability of a sub-
stance to cause
abnormal growth
or deformity in
developing fetus-
es (birth defects)
19. How is teratogenicity tested Administering
doses of chemical
to female test
animals at various
stages of
pregnancies and
observing
number of
miscarriages and
defective
offspring verses
what would
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
normally be
expected
20. Examples of animals used to test teratogenicity Rodents, rabbits,
dogs, monkeys
21. Effects of chemicals are usually considered signifi- They occur at dos-
cant for teratogenicity if... es not toxic by
themselves to the
mother
22. Testing for teratogenicity is standard part of pesticide Data gaps
registration although ___________ May exist for older
chemicals
23. Neurotoxicity Gradual damage
to basic nerve
structure. Does
not refer to re-
versible effects
24. Test animal for neurotoxicity Chicken
25. Hepatoxicity Damage to liver
26. Nephrotoxicity damage to the kid-
neys
27. Immunotoxicity Compromise im-
mune system
28. Fetotoxicity Direct toxic injury
or death of fetus
29. Hemotoxic effects Blood disorders
30. Cholinesterases Enzymes found in
humans, insects,
and other species
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
1. Chronic health effect Problems that de-
velop over a rela-
tively long period
of time, following
either one signifi-
cant exposure that
initiates a prob-
lem, or following a
series of small ex-
posures which ac-
cumulate in some
manner and result
in a development
of a disease or dis-
order
2. acute toxicity Poisoning from a
single dose over a
much shorter du-
ration of time
3. How soon do health effects occur from accrue toxic- Within 24 hours of
ity? exposure
4. Chronic health risk problems (major examples) Mutagenicity,
oncogenicity,
carcinogenicity,
teratogenicity,
neurotoxicity
5. Mutagenicity Ability of a sub-
stance or agent
to cause muta-
tions to genes or
chromosomes
6. Changes from mutagenicity are... Almost always
harmful
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
7. Tests to detect mutagenicity Varied. Tests on
cells to tests on
whole animals
8. It's believed that chemicals that cause mutations are Cancers
more likely to be ones that can also cause...
9. Why is mutation testing used as a first screen for new Faster and cheap-
compounds? er than animal life-
time testing
10. Oncogenicity The ability of a
chemical to cause
abnormal growths
or tumors in tis-
sues
11. Carcinogenicity Ability of a sub-
stance or agent
to cause malig-
nant tumors
12. How do they test chemicals for their ability to cause Administering dai-
tumors ly doses to ani-
mals for their en-
tire lifetime and
then dissecting
them to detect
presence of tu-
mors in the ani-
mals tissues
13. A rodent carcinogenicity study takes how long typi- 2-3 years
cally?
14. Pesticide companies are required to submit test data Several animal
on oncogenicity from.... species
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
15. There are currently how many pesticide active ingre- Over 70
dients considered known, likely, or probable carcino-
gens
16. MDAR Massachusetts
Department of
Agricultural
Resources
17. Act to protect children and families from harmful pes- Passed in 2000.
ticides Pesticide products
that contain car-
cinogens may not
be used in or
around schools,
daycares, or after
school programs
18. Teratogenicity Ability of a sub-
stance to cause
abnormal growth
or deformity in
developing fetus-
es (birth defects)
19. How is teratogenicity tested Administering
doses of chemical
to female test
animals at various
stages of
pregnancies and
observing
number of
miscarriages and
defective
offspring verses
what would
, MASSACHUSETTS PESTICIDE APPLICATOR CORE EXAM LATEST
2024-2025 ACTUAL EXAM ALL 400 QUESTIONS AND CORRECT DETAIL
ANSWERS WITH RATIONALES
Study online at https://quizlet.com/_g12t9m
normally be
expected
20. Examples of animals used to test teratogenicity Rodents, rabbits,
dogs, monkeys
21. Effects of chemicals are usually considered signifi- They occur at dos-
cant for teratogenicity if... es not toxic by
themselves to the
mother
22. Testing for teratogenicity is standard part of pesticide Data gaps
registration although ___________ May exist for older
chemicals
23. Neurotoxicity Gradual damage
to basic nerve
structure. Does
not refer to re-
versible effects
24. Test animal for neurotoxicity Chicken
25. Hepatoxicity Damage to liver
26. Nephrotoxicity damage to the kid-
neys
27. Immunotoxicity Compromise im-
mune system
28. Fetotoxicity Direct toxic injury
or death of fetus
29. Hemotoxic effects Blood disorders
30. Cholinesterases Enzymes found in
humans, insects,
and other species
