©Themoon EXAM SOLUTIONS
12/11/2024 4:18PM
Pharmacology 5334 Final Exam Questions
and Answers
PCN drug-drug interactions - Answers✓✓-aminoglycosides
-bacteriostatic antibiotics
-probenecid
Treatment for ONYCHOMYCOSIS - Answers✓✓Terbinafine (Lamisil) 1 tab daily x 3-6
months po
Best treatment for chlamydia - Answers✓✓Aziythromycin 1gm 1x dose
or
Doxycycline 100 mg po twice a day for 7 days
Patient with vaginal candidiasis, what is the treatment? - Answers✓✓Fluconazole 150mg po
once
Treatment for uncomplicated cervical gonorrhea - Answers✓✓Ceftriaxone, 250 mg IM once,
plus azithromycin, 1 g PO once
Patient with tinea capitis, what is the TX? - Answers✓✓Very difficult to treat topically
Griseofulium po 6-8 weeks
or
Terbinafine (Lamisil) po 2-4 weeks
Narrow Spectrum PCN - Answers✓✓PCN G (procaine), PCN G (benzathine), PCN V
Bugs they fight: GRAM(+) cocci- 1st drug of choice against Strep (pneumonia, pharyngitis,
endocarditis) , Clostridium (tetanus, anthrax, gas gangrene)Neisseria, spirochete (syphilis)
, ©Themoon EXAM SOLUTIONS
12/11/2024 4:18PM
Lauren comes into the clinic and is diagnosed with Trichomoniasis. The NP can prescribe: -
Answers✓✓Metronidazole, 2 g PO once or
Tinidazole, 2 g PO once
Penicillinase-resistant PCN - Answers✓✓Oxacillin, Nafacillin, Dicloxacillin
Bugs they fight: Staph
Broad spectrum PCN - Answers✓✓Ampicillin- ampiciliin/sulbactam (Unasyn)
Amoxicillin- amoxicillin/ER (Moxatog), Amoxicillin/Clavulanate(Augmentin)
Bugs they fight: Good against GRAM (-)H. influenza, e-coli, proteus mirabilis, enterococci,
salmonella and shigella
Extended Spectrum PCNs - Answers✓✓Piperacillin/tazobactam (Zosyn)
Bugs they fight: same as broad spectrum + pseudomonas, klebsiella, bacterial fragilis
Beta-lactamase inhibitors - Answers✓✓clavulanic acid, sulbactam, tazobactam
**Can not be given on their own, only in combo with PCN's i.e.> Augmentin, Unasyn, Zoysn
Cephalosporin Generation 1 - Answers✓✓-cephalexin
-cephazolin
-cephadoxil
**Cephlasporinase will destroy**
Not the drug of choice for active infections- good for prophylaxis prior to sx
Cephlasporin (2nd generation) - Answers✓✓Cefuroxime-most common
Bugs they fight: h.influenza (pneumonia), otitis sinusitis, res. tract infection
, ©Themoon EXAM SOLUTIONS
12/11/2024 4:18PM
Cephlasporin (3rd generation) - Answers✓✓Cefotaxime, Cefdinir, Cefixime, Cefodoxime,
Ceftaazidime, Ceftibuten, Ceftriaxone
**Can penetrate CSF fluid**
Bugs they fight: Great against GRAM (-) bacteria causing meningitis, h.influenza, klebsiella,
proteus, salmonella
Cephlasporin (4th generation) - Answers✓✓Cefepime-hospital associated pneumonia's &
Ceftolozone/tozobactam (Zerbaxa)- complicated UTI's and intraabdominal infections
Cephlasporin (5th generation) - Answers✓✓Ceftaroline (Teflaro)-MRSA
Cephalosporin and PCN - Answers✓✓Cross allergy w/PCN
Carbapenems - Answers✓✓Only 4: Imipenem, Meropenem, Ertrapenem, Doripenem
EXTREMELY broad spectrum, **only given IV**
not active against MRSA
Iminpenem-cilastatin - Answers✓✓Most effective antibiotic against anaerobic bacteria
Highly effective against Gram (+/) cocci & bacilli
Meropenem - Answers✓✓Bacterial meningitis-3m and up
Intraabdominal infections across ages
complicated skin infections
Ertrapenem (Invanz) - Answers✓✓Pelvic infections
Community acquired pneumonia
Complicated UTIs
Abdomen/skin infections
12/11/2024 4:18PM
Pharmacology 5334 Final Exam Questions
and Answers
PCN drug-drug interactions - Answers✓✓-aminoglycosides
-bacteriostatic antibiotics
-probenecid
Treatment for ONYCHOMYCOSIS - Answers✓✓Terbinafine (Lamisil) 1 tab daily x 3-6
months po
Best treatment for chlamydia - Answers✓✓Aziythromycin 1gm 1x dose
or
Doxycycline 100 mg po twice a day for 7 days
Patient with vaginal candidiasis, what is the treatment? - Answers✓✓Fluconazole 150mg po
once
Treatment for uncomplicated cervical gonorrhea - Answers✓✓Ceftriaxone, 250 mg IM once,
plus azithromycin, 1 g PO once
Patient with tinea capitis, what is the TX? - Answers✓✓Very difficult to treat topically
Griseofulium po 6-8 weeks
or
Terbinafine (Lamisil) po 2-4 weeks
Narrow Spectrum PCN - Answers✓✓PCN G (procaine), PCN G (benzathine), PCN V
Bugs they fight: GRAM(+) cocci- 1st drug of choice against Strep (pneumonia, pharyngitis,
endocarditis) , Clostridium (tetanus, anthrax, gas gangrene)Neisseria, spirochete (syphilis)
, ©Themoon EXAM SOLUTIONS
12/11/2024 4:18PM
Lauren comes into the clinic and is diagnosed with Trichomoniasis. The NP can prescribe: -
Answers✓✓Metronidazole, 2 g PO once or
Tinidazole, 2 g PO once
Penicillinase-resistant PCN - Answers✓✓Oxacillin, Nafacillin, Dicloxacillin
Bugs they fight: Staph
Broad spectrum PCN - Answers✓✓Ampicillin- ampiciliin/sulbactam (Unasyn)
Amoxicillin- amoxicillin/ER (Moxatog), Amoxicillin/Clavulanate(Augmentin)
Bugs they fight: Good against GRAM (-)H. influenza, e-coli, proteus mirabilis, enterococci,
salmonella and shigella
Extended Spectrum PCNs - Answers✓✓Piperacillin/tazobactam (Zosyn)
Bugs they fight: same as broad spectrum + pseudomonas, klebsiella, bacterial fragilis
Beta-lactamase inhibitors - Answers✓✓clavulanic acid, sulbactam, tazobactam
**Can not be given on their own, only in combo with PCN's i.e.> Augmentin, Unasyn, Zoysn
Cephalosporin Generation 1 - Answers✓✓-cephalexin
-cephazolin
-cephadoxil
**Cephlasporinase will destroy**
Not the drug of choice for active infections- good for prophylaxis prior to sx
Cephlasporin (2nd generation) - Answers✓✓Cefuroxime-most common
Bugs they fight: h.influenza (pneumonia), otitis sinusitis, res. tract infection
, ©Themoon EXAM SOLUTIONS
12/11/2024 4:18PM
Cephlasporin (3rd generation) - Answers✓✓Cefotaxime, Cefdinir, Cefixime, Cefodoxime,
Ceftaazidime, Ceftibuten, Ceftriaxone
**Can penetrate CSF fluid**
Bugs they fight: Great against GRAM (-) bacteria causing meningitis, h.influenza, klebsiella,
proteus, salmonella
Cephlasporin (4th generation) - Answers✓✓Cefepime-hospital associated pneumonia's &
Ceftolozone/tozobactam (Zerbaxa)- complicated UTI's and intraabdominal infections
Cephlasporin (5th generation) - Answers✓✓Ceftaroline (Teflaro)-MRSA
Cephalosporin and PCN - Answers✓✓Cross allergy w/PCN
Carbapenems - Answers✓✓Only 4: Imipenem, Meropenem, Ertrapenem, Doripenem
EXTREMELY broad spectrum, **only given IV**
not active against MRSA
Iminpenem-cilastatin - Answers✓✓Most effective antibiotic against anaerobic bacteria
Highly effective against Gram (+/) cocci & bacilli
Meropenem - Answers✓✓Bacterial meningitis-3m and up
Intraabdominal infections across ages
complicated skin infections
Ertrapenem (Invanz) - Answers✓✓Pelvic infections
Community acquired pneumonia
Complicated UTIs
Abdomen/skin infections
