Antibiotics Acute Care Nurse Practitioner ACNP
2024 Exam Quiz Study Guide- Qs & As
4th generation PCN Correct Ans-Pipercillin - even greater penetration into tough to crack
bacteria like pseudomonas, looses some coverage of klebsiella. Used for primarily pseudomonas
coverage combined others
PCN family - beta lactamase inhibitors Correct Ans-expand gram negative coverage w/ added
MSSA coverage
Beta Lactamase Inhibitors Correct Ans-Amox/Clavulanic Acid PO (augmentin) --> complete
coverage of strep, MSSA, gram - enterics like ecoli, klebsiella & very well anaerobes
Ampicillin/Sulbactam (Unasyn) IV equivalent of above w/ superior klebsiella coverage so
perfect for intraabdominal process
Pip/Tazo (Zosyn) IV --> adds pseudomonas coverage of piperacillin to above
Monobactams Correct Ans-loose one ring of the typical structure so loose G+ coverage - gain
broad G - coverage
some enterococus coverage, enterics well, non enterics somewhat
Carbapenems Correct Ans-meropenem, imipenem, entrapenem
cefepime equivalent - big gun for gram -
, Bactrim (TMP/SMX) Correct Ans-inhibits bacterial DNA synthesis
many side effects
g+ coverage --> strep pretty well, MSSA/MRSA fairly well, some enteric coverage, some
atypical coverage (not used for this)
COPD flair
Macrolides Correct Ans-interfere w/ protein transcription
erythromycin, azythromycin, clarithromycin (mycin does not equal macrolide)
no g+ coverage
some coverage of enterics/nonenterics
covers pharynx bugs like hflu well
COMPLETE COVERAGE OF ATYPICALS
Clindamycin Correct Ans-same mechanism as macrolides
anaerobes above the neck, MRSA and STAPH well
clinda = mouth infection
Fluroquinolones Correct Ans-DNA gyrase inhibitor
levo, cipro
COMPLETE COVERAGE OF ATYPICALS
enterics pretty well, some coverage of non enterics, complete coverage of pharynx bugs like H
flu
2024 Exam Quiz Study Guide- Qs & As
4th generation PCN Correct Ans-Pipercillin - even greater penetration into tough to crack
bacteria like pseudomonas, looses some coverage of klebsiella. Used for primarily pseudomonas
coverage combined others
PCN family - beta lactamase inhibitors Correct Ans-expand gram negative coverage w/ added
MSSA coverage
Beta Lactamase Inhibitors Correct Ans-Amox/Clavulanic Acid PO (augmentin) --> complete
coverage of strep, MSSA, gram - enterics like ecoli, klebsiella & very well anaerobes
Ampicillin/Sulbactam (Unasyn) IV equivalent of above w/ superior klebsiella coverage so
perfect for intraabdominal process
Pip/Tazo (Zosyn) IV --> adds pseudomonas coverage of piperacillin to above
Monobactams Correct Ans-loose one ring of the typical structure so loose G+ coverage - gain
broad G - coverage
some enterococus coverage, enterics well, non enterics somewhat
Carbapenems Correct Ans-meropenem, imipenem, entrapenem
cefepime equivalent - big gun for gram -
, Bactrim (TMP/SMX) Correct Ans-inhibits bacterial DNA synthesis
many side effects
g+ coverage --> strep pretty well, MSSA/MRSA fairly well, some enteric coverage, some
atypical coverage (not used for this)
COPD flair
Macrolides Correct Ans-interfere w/ protein transcription
erythromycin, azythromycin, clarithromycin (mycin does not equal macrolide)
no g+ coverage
some coverage of enterics/nonenterics
covers pharynx bugs like hflu well
COMPLETE COVERAGE OF ATYPICALS
Clindamycin Correct Ans-same mechanism as macrolides
anaerobes above the neck, MRSA and STAPH well
clinda = mouth infection
Fluroquinolones Correct Ans-DNA gyrase inhibitor
levo, cipro
COMPLETE COVERAGE OF ATYPICALS
enterics pretty well, some coverage of non enterics, complete coverage of pharynx bugs like H
flu
