ACNP--Rosh review Questions and
Answers
What is a Mallory-Weiss tear? Signs? Correct Ans-tear of distal esophagus and proximal
stomach caused by forceful retching (usually pt with hx of alcoholism and hiatal hernia. Signs
include hematemesis and epigastric or back pain. Endoscopy is requried to make diagnosis.
Charcot's triad Correct Ans-RUQ pain, jaundice, and fever/chills in the setting of ascending
cholangitis
Depression Symptoms Correct Ans-SIG E CAPS (sleep, interest, guilt, energy, cognition,
appetite, psychomotor (restless), suicide)
What is Low-intensity statin therapy? Correct Ans-Lowers by 30%, Simvastatin 10mg,
Pravastatin 10mg, Lovastatin, 20 mg, Fluvastatin 20-40mg)
What is Moderate-intensity statin therapy? Correct Ans-Atorvastatin 10-20 mg
Rosuvastatin 10 mg
Simvastatin 20-40 mg
Pravastatin 40-80 mg
Lovastatin 40 mg
Fluvastatin XL 80 mg
Pitavastatin 2-4 mg
, What is high-intensity statin therapy? Correct Ans-Atorvastatin 40-80 mg
Rosuvastatin 20-40 mg
Hemophilia B is Correct Ans-genetically inherited deficiency in factor IX associated with
prolonged aPTT. PT may be normal. Treatment with Factor IX concentrate.
Hemophilia A is Correct Ans-X-linked recessive, decreased synthesis of Fctor VIII, treatment
with recombinant FActor VIII
Von Willebrand Disease Correct Ans-bleeding disorder caused by a deficiency of von
Willebrand factor, a "sticky" protein that lines blood vessels and reacts with platelets to form a
plug that leads to clot formation (most common genetic coagulopathy); Treated with nasal
DDAVP.
Pulmonary HTN functional class II Correct Ans-slight limitation of physical activity. They
are comfortable at rest. Ordinary physical activity causes undue dyspnea or fatigue, chest pain or
near syncope.
Pulmonary HTN functional class III Correct Ans-marked limitation of physical activity. They
are comfortable at rest. Less than ordinary activity causes undue dyspnea or fatigue, chest pain or
near syncope.
Pulmonary HTN functional class IV Correct Ans-inability to carry out any physical activity
without symptoms. These patients manifest signs of right heart failure. Dyspnea and/or fatigue
may even be present at rest. Discomfort is increased by any physical activity.
Answers
What is a Mallory-Weiss tear? Signs? Correct Ans-tear of distal esophagus and proximal
stomach caused by forceful retching (usually pt with hx of alcoholism and hiatal hernia. Signs
include hematemesis and epigastric or back pain. Endoscopy is requried to make diagnosis.
Charcot's triad Correct Ans-RUQ pain, jaundice, and fever/chills in the setting of ascending
cholangitis
Depression Symptoms Correct Ans-SIG E CAPS (sleep, interest, guilt, energy, cognition,
appetite, psychomotor (restless), suicide)
What is Low-intensity statin therapy? Correct Ans-Lowers by 30%, Simvastatin 10mg,
Pravastatin 10mg, Lovastatin, 20 mg, Fluvastatin 20-40mg)
What is Moderate-intensity statin therapy? Correct Ans-Atorvastatin 10-20 mg
Rosuvastatin 10 mg
Simvastatin 20-40 mg
Pravastatin 40-80 mg
Lovastatin 40 mg
Fluvastatin XL 80 mg
Pitavastatin 2-4 mg
, What is high-intensity statin therapy? Correct Ans-Atorvastatin 40-80 mg
Rosuvastatin 20-40 mg
Hemophilia B is Correct Ans-genetically inherited deficiency in factor IX associated with
prolonged aPTT. PT may be normal. Treatment with Factor IX concentrate.
Hemophilia A is Correct Ans-X-linked recessive, decreased synthesis of Fctor VIII, treatment
with recombinant FActor VIII
Von Willebrand Disease Correct Ans-bleeding disorder caused by a deficiency of von
Willebrand factor, a "sticky" protein that lines blood vessels and reacts with platelets to form a
plug that leads to clot formation (most common genetic coagulopathy); Treated with nasal
DDAVP.
Pulmonary HTN functional class II Correct Ans-slight limitation of physical activity. They
are comfortable at rest. Ordinary physical activity causes undue dyspnea or fatigue, chest pain or
near syncope.
Pulmonary HTN functional class III Correct Ans-marked limitation of physical activity. They
are comfortable at rest. Less than ordinary activity causes undue dyspnea or fatigue, chest pain or
near syncope.
Pulmonary HTN functional class IV Correct Ans-inability to carry out any physical activity
without symptoms. These patients manifest signs of right heart failure. Dyspnea and/or fatigue
may even be present at rest. Discomfort is increased by any physical activity.
