©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
Quiz 1 Pharmacology 5334 Study Guide.
PCN drug-drug interactions - answer✔-aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - answer✔-cephalexin
-cephazolin
-cephadoxil
Cephalosporin and PCN - answer✔Cross allergy w/PCN
Carbapenems - answer✔not active against MRSA
Vancomycin treats - answer✔gram positive
Vancomycin AE - answer✔ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - answer✔Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it increases
mortality
Monobactams treats - answer✔gram negative aerobic
Fosfomycin treats - answer✔enterococcus and Ecoli
Aminoglycosides treat - answer✔gram negative bacilli
Aminoglycosides adverse effects - answer✔ototoxicity and nephrotoxicity
aminoglycosides peak and trough - answer✔Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero)
Sulfonamides MOA - answer✔inhibit folic acid synthesis
UTI drugs - answer✔1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - answer✔TMP/SMZ, Cipro, Levo, augmentin, cephalexin
, ©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
recurrent UTI prophylaxis - answer✔TMP
Recurrent UTI other tx - answer✔SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos.
Acute Bact Prostatitis Tx - answer✔Floxacins
Tetracycline adverse effects - answer✔-Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - answer✔-magnesium laxative
-antacids
-Calcium
-iron sup.
-milk
tetracycline treats - answer✔-lyme dx
-anthrax
-helicobacter pylori
-mycoplasma
Linezolid treats - answer✔VRE and MRSA
Telithromycin BBW - answer✔muscle weakness w/myasthenia gravis
Dalfopristin/Quinupristin BBW - answer✔reserve only for infection when not responding to vanco. to
delay resistance
Chloramphenicol BBW - answer✔fatal aplastic anemia
Retapamulin and mupirocin tx - answer✔topical treatment for impetigo
Mupirocin (topical) - answer✔MRSA in nostrils
TB treatment - answer✔RIPE (rifampin, isoniazid, pyrazinamide, ethambutol); rifapentine and rifabutin
TB treatment is effective when - answer✔no mycobacteria in sputum and no colonies present in culture
11/9/2024 2:18 PM
Quiz 1 Pharmacology 5334 Study Guide.
PCN drug-drug interactions - answer✔-aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - answer✔-cephalexin
-cephazolin
-cephadoxil
Cephalosporin and PCN - answer✔Cross allergy w/PCN
Carbapenems - answer✔not active against MRSA
Vancomycin treats - answer✔gram positive
Vancomycin AE - answer✔ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - answer✔Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it increases
mortality
Monobactams treats - answer✔gram negative aerobic
Fosfomycin treats - answer✔enterococcus and Ecoli
Aminoglycosides treat - answer✔gram negative bacilli
Aminoglycosides adverse effects - answer✔ototoxicity and nephrotoxicity
aminoglycosides peak and trough - answer✔Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero)
Sulfonamides MOA - answer✔inhibit folic acid synthesis
UTI drugs - answer✔1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - answer✔TMP/SMZ, Cipro, Levo, augmentin, cephalexin
, ©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
recurrent UTI prophylaxis - answer✔TMP
Recurrent UTI other tx - answer✔SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos.
Acute Bact Prostatitis Tx - answer✔Floxacins
Tetracycline adverse effects - answer✔-Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - answer✔-magnesium laxative
-antacids
-Calcium
-iron sup.
-milk
tetracycline treats - answer✔-lyme dx
-anthrax
-helicobacter pylori
-mycoplasma
Linezolid treats - answer✔VRE and MRSA
Telithromycin BBW - answer✔muscle weakness w/myasthenia gravis
Dalfopristin/Quinupristin BBW - answer✔reserve only for infection when not responding to vanco. to
delay resistance
Chloramphenicol BBW - answer✔fatal aplastic anemia
Retapamulin and mupirocin tx - answer✔topical treatment for impetigo
Mupirocin (topical) - answer✔MRSA in nostrils
TB treatment - answer✔RIPE (rifampin, isoniazid, pyrazinamide, ethambutol); rifapentine and rifabutin
TB treatment is effective when - answer✔no mycobacteria in sputum and no colonies present in culture
