©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
NURS 5334 Advanced Pharmacology Module
1 Exam Questions And Answers 100% Pass
What is prescriptive authority? - answer✔Legal right to prescribe drugs
Varies for nonphysician providers
Limitations tied to oversight by MD or DO
Arguments for full prescriptive authority - answer✔- APRNs are educated to practice and prescribe
independently without supervision
- National examinations validate ability to provide safe competent care
- Licensure ensures compliance with standards to promote public health and safety - Limited
prescriptive authority creates numerous barriers to quality, affordable, & accessible patient care
Drug selection factors - answer✔cost, guidelines, availability, interactions, side effects, allergies, liver &
renal function, need for monitoring, special populations
Elements needed to complete a prescription - answer✔- Prescriber name, license number, and contact
information
- Prescriber DEA number, if applicable
- Patient name and date of birth
- Patient allergies
- Name of medication
- Indication of medication
- Medication strength (e.g., 25 mg, 500 mg/mL)
- Dose of medication and frequency (e.g., 12.5 mg once daily)
- Number of tablets/capsules to dispense
- Number of refills
, ©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
Pharmokinetics - answer✔the study of drugs within the body, absorption , distribution, metabolism,
excretion
3 ways drugs cross cell membrane - answer✔1. channels & pores
2. transport systems (p glycoprotein)
3. direct penetration of membrane ( most common -> drugs too large to pass through pores & channels)
absorption - answer✔the movement of a drug from its site of administration into the blood
rate of absorption determines how soon effects will begin
amount of absorption determine intensity of effects
factors affecting absorption - answer✔rate of dissolution, surface area, blood flow, lipid solubility, pH
partitioning
P-glycoprotein - answer✔Transmembrane protein that transports a wide variety of drugs out of cells
How does the liver aid in pharmacokinetics? - answer✔transports drugs into bile for elimination
How do the kidneys aid in pharmacokinetics? - answer✔pumps drugs into urine for excretion
How does the placenta aid in pharmacokinetics? - answer✔transports drugs back into the maternal
blood
How does the brain aid in pharmacokinetics? - answer✔pumps drugs into blood to limit drugs' access to
the brain
passive diffusion - answer✔molecules move from one side of a barrier to another without expending
energy; moving from an area of higher concentration to lower concentration
"like dissolves like" rule - answer✔Cell membranes are composed primarily of lipids; therefore, to
directly penetrate membranes, a drug must be lipid soluble (lipophilic)
polar molecules - answer✔Molecules that have an unequal distribution of charges
No net charge
ions - answer✔molecules that have a net electrical charge
quaternary ammonium compounds - answer✔molecules that contain at least 1 atom of nitrogen and
carry a positive charge at all times
pH dependent ionization - answer✔Acid is a proton donor - tends to ionize in basic (alkaline) media
11/9/2024 2:18 PM
NURS 5334 Advanced Pharmacology Module
1 Exam Questions And Answers 100% Pass
What is prescriptive authority? - answer✔Legal right to prescribe drugs
Varies for nonphysician providers
Limitations tied to oversight by MD or DO
Arguments for full prescriptive authority - answer✔- APRNs are educated to practice and prescribe
independently without supervision
- National examinations validate ability to provide safe competent care
- Licensure ensures compliance with standards to promote public health and safety - Limited
prescriptive authority creates numerous barriers to quality, affordable, & accessible patient care
Drug selection factors - answer✔cost, guidelines, availability, interactions, side effects, allergies, liver &
renal function, need for monitoring, special populations
Elements needed to complete a prescription - answer✔- Prescriber name, license number, and contact
information
- Prescriber DEA number, if applicable
- Patient name and date of birth
- Patient allergies
- Name of medication
- Indication of medication
- Medication strength (e.g., 25 mg, 500 mg/mL)
- Dose of medication and frequency (e.g., 12.5 mg once daily)
- Number of tablets/capsules to dispense
- Number of refills
, ©THEBRIGHT EXAM SOLUTIONS
11/9/2024 2:18 PM
Pharmokinetics - answer✔the study of drugs within the body, absorption , distribution, metabolism,
excretion
3 ways drugs cross cell membrane - answer✔1. channels & pores
2. transport systems (p glycoprotein)
3. direct penetration of membrane ( most common -> drugs too large to pass through pores & channels)
absorption - answer✔the movement of a drug from its site of administration into the blood
rate of absorption determines how soon effects will begin
amount of absorption determine intensity of effects
factors affecting absorption - answer✔rate of dissolution, surface area, blood flow, lipid solubility, pH
partitioning
P-glycoprotein - answer✔Transmembrane protein that transports a wide variety of drugs out of cells
How does the liver aid in pharmacokinetics? - answer✔transports drugs into bile for elimination
How do the kidneys aid in pharmacokinetics? - answer✔pumps drugs into urine for excretion
How does the placenta aid in pharmacokinetics? - answer✔transports drugs back into the maternal
blood
How does the brain aid in pharmacokinetics? - answer✔pumps drugs into blood to limit drugs' access to
the brain
passive diffusion - answer✔molecules move from one side of a barrier to another without expending
energy; moving from an area of higher concentration to lower concentration
"like dissolves like" rule - answer✔Cell membranes are composed primarily of lipids; therefore, to
directly penetrate membranes, a drug must be lipid soluble (lipophilic)
polar molecules - answer✔Molecules that have an unequal distribution of charges
No net charge
ions - answer✔molecules that have a net electrical charge
quaternary ammonium compounds - answer✔molecules that contain at least 1 atom of nitrogen and
carry a positive charge at all times
pH dependent ionization - answer✔Acid is a proton donor - tends to ionize in basic (alkaline) media
