ONS/ONCC Chemotherapy Immunotherapy
Certification Exams | Already passed
What are regulatory t-cells also known as? - ✔✔supressor t-cells
What do regulatory t-cells do? - ✔✔regulate the immune response to prevent autoimmune reactions
and limit inflammatory responses
What are cytokines? - ✔✔cytokines are secreted by lymphocytes with the intention of stimulating
macrophages and cytotoxic t lymphocytes to identify and kill pathogen infected cells or tumor cells
What do proto-oncogenes do? - ✔✔regulate normal cell growth and division.
What are proto-oncogenes? - ✔✔they are a large family of genes that code for proteins and
enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and become what? -
✔✔oncogene
What are two examples of an oncogene? - ✔✔EGFR/Erb- B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - ✔✔p53
What is the p53 gene also called? - ✔✔suicide gene
, What does neoadjuvant therapy refer to? - ✔✔treatment given as a first step to shrink a tumor before
the main treatment
What is adjuvant therapy? - ✔✔additional cancer treatment given after the primary treatment to
lower the risk that cancer will occur
How do alkylating agents function? - ✔✔by causing a break in the DNA helix strand, causing
interference with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? - ✔✔cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's different? - ✔✔platinum based chemo's do
not have the molecule to to attach to and destroy DNA
What are the two most common platinum based chemo's? - ✔✔cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? - ✔✔to avoid exposure to cold air
and consuming cold fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - ✔✔streptozocin and semustine
What are the most common side effects of antimetabolites? - ✔✔myelosuppresion, GI
toxicities, photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - ✔✔antitumor antibiotics
What are examples of anthracyclines that? - ✔✔doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - ✔✔cardiotoxicity
Certification Exams | Already passed
What are regulatory t-cells also known as? - ✔✔supressor t-cells
What do regulatory t-cells do? - ✔✔regulate the immune response to prevent autoimmune reactions
and limit inflammatory responses
What are cytokines? - ✔✔cytokines are secreted by lymphocytes with the intention of stimulating
macrophages and cytotoxic t lymphocytes to identify and kill pathogen infected cells or tumor cells
What do proto-oncogenes do? - ✔✔regulate normal cell growth and division.
What are proto-oncogenes? - ✔✔they are a large family of genes that code for proteins and
enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and become what? -
✔✔oncogene
What are two examples of an oncogene? - ✔✔EGFR/Erb- B1 and Erb-B2/HER2
What is a very important tumor suppressor gene? - ✔✔p53
What is the p53 gene also called? - ✔✔suicide gene
, What does neoadjuvant therapy refer to? - ✔✔treatment given as a first step to shrink a tumor before
the main treatment
What is adjuvant therapy? - ✔✔additional cancer treatment given after the primary treatment to
lower the risk that cancer will occur
How do alkylating agents function? - ✔✔by causing a break in the DNA helix strand, causing
interference with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? - ✔✔cytoxan, ifos, bendamustine
How are alkylating agents and platinum based chemo's different? - ✔✔platinum based chemo's do
not have the molecule to to attach to and destroy DNA
What are the two most common platinum based chemo's? - ✔✔cisplatin and carboplatin
What should you instruct patients to do when receiving oxaliplatin? - ✔✔to avoid exposure to cold air
and consuming cold fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - ✔✔streptozocin and semustine
What are the most common side effects of antimetabolites? - ✔✔myelosuppresion, GI
toxicities, photosensitivity, hand foot syndrome,
What kind of chemo therapy require life time doses? - ✔✔antitumor antibiotics
What are examples of anthracyclines that? - ✔✔doxorubicin, daunarubicin, epirubicin, idarubicin
What are lifetime doses needed for anthrcyclines? - ✔✔cardiotoxicity
