BLOO
D
Plasma – liquid ECM of blood
Formed elements – include cells and cell fragments found suspended in plasma
Centrifuged – 3 Layers of Blood
Top Layer – 55% Plasma
Middle Layer – 1% Leukocytes and Platelets
Bottom Layer – 44% Erythrocytes
HEMATOCRIT – MEASUREMENT OF PERCENTAGE OF BLOOD COMPOSED OF RED BLOOD
CELLS. DIAGNOSTIC TEST
BLOOD FUNCTIONS –
Exchanging
Distributing solutes
Performing immune
Maintaining body
Functioning in blood clotting
Preserving acid-base Homeostasis
Stabilizing blood pressure:
Plasma –
Pale Yellow Liquid
90% Water
Determining Viscosity
Resistant to Flow
Less Water in Plasma, More Formed Elements, Resulting Blood to Not
Flow as Easy, Making Heart to Work Harder.
Plasma Proteins
Portion of plasma Can’t dissolve in water, TOO BIG.
, 9% of Plasma.
Form Colloid – 2 Components not able to dissolve in one another
Albumin – BLOOD OSMOTIC PRESSURE
Bring water back into blood vessel
Immune Proteins – (g-globulins); also, known as antibodies; made by
leukocytes, components of immune system
Transport proteins – bind to lipid-based molecules that otherwise are
incompatible with mostly water-based plasma; allows transportation of
these molecules in blood
Clotting proteins – stop bleeding from injured blood vessels by
forming a blood clot with assistance from platelets
Solution in Plasma
1 % forms a Solution, which dissolves in water
Like Glucose, Amino Acids, Oxygen, Carbon Dioxide, and Wastes
Can be exchanged between Blood and Interstitial Fluid in Capillary Beds
Erythrocytes –
RED Blood Cells (RBCs) – Bus Drivers
Circular Bi- Concave Structure – Flattened Donut Shaped Concave on
Both Sides
Shape Helps to Perform Function
ANUCLEATED - After they MATURE & are Produced in Bone Marrow,
DO NOT HAVE A NUCLEUS, Making More Room for Oxygen Storage.
(HEMOGLOBIN)
As Cell Matures, It Loses Its Nucleus
CREATES ROOM FOR CYTOSOL IN ENZYMES; Inside of RBCs Many
Proteins – 1 BILLION OXYGEN BINDING - HEMOGLOBIN
Transport Oxygen INTO Body and Carbon Dioxide OUT of The Body
Bus Drivers Transport Citizens All Over the City, Erythrocytes Transport
Oxygen All throughout the Body.
Citizens are important to City, Like Oxygen is Important to Body
HEMOGLOBIN –
Composed of 4 Polypeptide Chains
Quaternary Structure of Protein Structure
2 Alpha Chains; 2 Beta Chains
EACH POLYPEPTIDE CHAIN OF HEMOGLOBIN HAS A HEME GROUP
HEME GROUP- HAS IRON
D
Plasma – liquid ECM of blood
Formed elements – include cells and cell fragments found suspended in plasma
Centrifuged – 3 Layers of Blood
Top Layer – 55% Plasma
Middle Layer – 1% Leukocytes and Platelets
Bottom Layer – 44% Erythrocytes
HEMATOCRIT – MEASUREMENT OF PERCENTAGE OF BLOOD COMPOSED OF RED BLOOD
CELLS. DIAGNOSTIC TEST
BLOOD FUNCTIONS –
Exchanging
Distributing solutes
Performing immune
Maintaining body
Functioning in blood clotting
Preserving acid-base Homeostasis
Stabilizing blood pressure:
Plasma –
Pale Yellow Liquid
90% Water
Determining Viscosity
Resistant to Flow
Less Water in Plasma, More Formed Elements, Resulting Blood to Not
Flow as Easy, Making Heart to Work Harder.
Plasma Proteins
Portion of plasma Can’t dissolve in water, TOO BIG.
, 9% of Plasma.
Form Colloid – 2 Components not able to dissolve in one another
Albumin – BLOOD OSMOTIC PRESSURE
Bring water back into blood vessel
Immune Proteins – (g-globulins); also, known as antibodies; made by
leukocytes, components of immune system
Transport proteins – bind to lipid-based molecules that otherwise are
incompatible with mostly water-based plasma; allows transportation of
these molecules in blood
Clotting proteins – stop bleeding from injured blood vessels by
forming a blood clot with assistance from platelets
Solution in Plasma
1 % forms a Solution, which dissolves in water
Like Glucose, Amino Acids, Oxygen, Carbon Dioxide, and Wastes
Can be exchanged between Blood and Interstitial Fluid in Capillary Beds
Erythrocytes –
RED Blood Cells (RBCs) – Bus Drivers
Circular Bi- Concave Structure – Flattened Donut Shaped Concave on
Both Sides
Shape Helps to Perform Function
ANUCLEATED - After they MATURE & are Produced in Bone Marrow,
DO NOT HAVE A NUCLEUS, Making More Room for Oxygen Storage.
(HEMOGLOBIN)
As Cell Matures, It Loses Its Nucleus
CREATES ROOM FOR CYTOSOL IN ENZYMES; Inside of RBCs Many
Proteins – 1 BILLION OXYGEN BINDING - HEMOGLOBIN
Transport Oxygen INTO Body and Carbon Dioxide OUT of The Body
Bus Drivers Transport Citizens All Over the City, Erythrocytes Transport
Oxygen All throughout the Body.
Citizens are important to City, Like Oxygen is Important to Body
HEMOGLOBIN –
Composed of 4 Polypeptide Chains
Quaternary Structure of Protein Structure
2 Alpha Chains; 2 Beta Chains
EACH POLYPEPTIDE CHAIN OF HEMOGLOBIN HAS A HEME GROUP
HEME GROUP- HAS IRON
