PCB 3233 IMMUNOLOGY - EXAM 3 questions with answers
Which cell types can become a plasma cell? - ** VERIFIED ANSWERS **✔✔All the above (a
memory B-cell, an activated B-cell, a centrocyte
The types of human MHC II presenting molecules are: - ** VERIFIED ANSWERS **✔✔HLA-DP,
HLA-DQ, HLA-DR which present peptide to CD4 T-cells
__________ has an alpha chain and a beta chain in their structure while ________ only has an alpha
chain in its structure? - ** VERIFIED ANSWERS **✔✔MHC II, MHC I
What process(es) are used after activation to make MHC I and II binding sites better? - ** VERIFIED
ANSWERS **✔✔None of the above (Somatic recombination, somatic hypermutation, isotype
switching
Burkitt's lymphoma is due to a translocation of the ________ gene next of one of the ________
genes. - ** VERIFIED ANSWERS **✔✔MYC, Ig
You would expect the IgA and IgB genes to be turned on (expressed) during which stage/s? - **
VERIFIED ANSWERS **✔✔All the above (the small pre B cell, mature B cell, immature B cell
T-cell receptor diversity is established - ** VERIFIED ANSWERS **✔✔Before antigen stimulation
The types of human MHC I presenting molecules are: - ** VERIFIED ANSWERS **✔✔HLA-A,
HLA-B and HLA-C which present peptide to CD8 T-cells
Receptor editing - ** VERIFIED ANSWERS **✔✔A & B (is done on the light chain, can be utilized
in an attempt to rescue a B-cell that has a self-reactive receptor
, Which one of the following is in the correct sequence? - ** VERIFIED ANSWERS **✔✔Early Pro-B,
Late Pro-B, Large Pre-B, Small Pre-B, Immature B-cell
When/where are N and P nucleotide additions added to the variable regions (binding site? - **
VERIFIED ANSWERS **✔✔During somatic recombination
Which chemokine/s call/s a B-cell into the follicle of a secondary lymphoid tissue? - ** VERIFIED
ANSWERS **✔✔CXCL 13
Which cell/s is/are lymphocyte/s? - ** VERIFIED ANSWERS **✔✔None of the above (neutrophils,
macrophages, dendritic cells
Which of the following is/are considered proto-oncogenes? - ** VERIFIED ANSWERS **✔✔A & B
(BCL2, MYC)
A mature B-cell has: - ** VERIFIED ANSWERS **✔✔IgM, IgD and IgA and IgB on the surface
True of false: CCL19 and CCL21 direct a B-cell out of the blood stream, across HEV's and into a
secondary lymphocyte toward the T-cell era. - ** VERIFIED ANSWERS **✔✔True
The peptide-binding groove of an MHC class I molecule is composed of the following extracelllular
dendritic cells? - ** VERIFIED ANSWERS **✔✔a1 : a2
A beta (B) chain of a TCR has: - ** VERIFIED ANSWERS **✔✔1 variable region and 1 constant
region
The genetic diversity of the MHC molecules binding site is due to: - ** VERIFIED ANSWERS
**✔✔Genetic polymorphism
Follicular dendritic cells: - ** VERIFIED ANSWERS **✔✔A & B (are present in germinal centers,
are present in secondary lymphoid
Which cell types can become a plasma cell? - ** VERIFIED ANSWERS **✔✔All the above (a
memory B-cell, an activated B-cell, a centrocyte
The types of human MHC II presenting molecules are: - ** VERIFIED ANSWERS **✔✔HLA-DP,
HLA-DQ, HLA-DR which present peptide to CD4 T-cells
__________ has an alpha chain and a beta chain in their structure while ________ only has an alpha
chain in its structure? - ** VERIFIED ANSWERS **✔✔MHC II, MHC I
What process(es) are used after activation to make MHC I and II binding sites better? - ** VERIFIED
ANSWERS **✔✔None of the above (Somatic recombination, somatic hypermutation, isotype
switching
Burkitt's lymphoma is due to a translocation of the ________ gene next of one of the ________
genes. - ** VERIFIED ANSWERS **✔✔MYC, Ig
You would expect the IgA and IgB genes to be turned on (expressed) during which stage/s? - **
VERIFIED ANSWERS **✔✔All the above (the small pre B cell, mature B cell, immature B cell
T-cell receptor diversity is established - ** VERIFIED ANSWERS **✔✔Before antigen stimulation
The types of human MHC I presenting molecules are: - ** VERIFIED ANSWERS **✔✔HLA-A,
HLA-B and HLA-C which present peptide to CD8 T-cells
Receptor editing - ** VERIFIED ANSWERS **✔✔A & B (is done on the light chain, can be utilized
in an attempt to rescue a B-cell that has a self-reactive receptor
, Which one of the following is in the correct sequence? - ** VERIFIED ANSWERS **✔✔Early Pro-B,
Late Pro-B, Large Pre-B, Small Pre-B, Immature B-cell
When/where are N and P nucleotide additions added to the variable regions (binding site? - **
VERIFIED ANSWERS **✔✔During somatic recombination
Which chemokine/s call/s a B-cell into the follicle of a secondary lymphoid tissue? - ** VERIFIED
ANSWERS **✔✔CXCL 13
Which cell/s is/are lymphocyte/s? - ** VERIFIED ANSWERS **✔✔None of the above (neutrophils,
macrophages, dendritic cells
Which of the following is/are considered proto-oncogenes? - ** VERIFIED ANSWERS **✔✔A & B
(BCL2, MYC)
A mature B-cell has: - ** VERIFIED ANSWERS **✔✔IgM, IgD and IgA and IgB on the surface
True of false: CCL19 and CCL21 direct a B-cell out of the blood stream, across HEV's and into a
secondary lymphocyte toward the T-cell era. - ** VERIFIED ANSWERS **✔✔True
The peptide-binding groove of an MHC class I molecule is composed of the following extracelllular
dendritic cells? - ** VERIFIED ANSWERS **✔✔a1 : a2
A beta (B) chain of a TCR has: - ** VERIFIED ANSWERS **✔✔1 variable region and 1 constant
region
The genetic diversity of the MHC molecules binding site is due to: - ** VERIFIED ANSWERS
**✔✔Genetic polymorphism
Follicular dendritic cells: - ** VERIFIED ANSWERS **✔✔A & B (are present in germinal centers,
are present in secondary lymphoid
