CSB601 EXAM STUDY GUIDE
Beta Blockers- active ingredient/ drug name - Answer Atenolol, Bisoprolol, Carvedilol
Beta blockers suffix - Answer -olol
beta blockers Mechanism of action - Answer Competitively block beta receptors, reduce
heart rate, BP, and cardiac contractility
beta blockers Therapeutic Indications - Answer Common uses include a range of
cardiovascular conditions (e.g. hypertension, angina, MI, tachyarrhythmias, heart
failure) and the prevention of migraine.
beta blockers side effects - Answer - bradycardia
- hypotension
- orthostatic hypotension (especially carvedilol, labetalol)
- transient worsening of heart failure (when treatment starts)
- nausea
- diarrhoea
ACE Inhibitors- active ingredient - Answer (Angiotensin Converting Enzyme Inhibitors)-
Perindopril, Captopril, Enalapril
ACE Inhibitors suffix - Answer -pril
ACE inhibitor Mechanism of action - Answer block conversion of angiotensin I to
angiotensin II and also inhibit the breakdown of bradykinin.
ACE inhibitors therapeutic indicators - Answer Hypertension, Chronic heart failure with
reduced ejection fraction as part of standard treatment. Diabetic nephropathy.
Prevention of progressive renal failure in patients with persistent proteinuria (>1 g
daily). Post MI.
ACE inhibitors side effects - Answer - hypotension
- headache
- dizziness
- cough
- Hyperkalaemia
- Fatigue
, - Nausea
- Renal impairment
Sartans- active ingredient - Answer Candesartan, Eprosartan, Irbesartan
sartans- suffix - Answer -sartan
sartans mechanism of action - Answer Competitively block binding of angiotensin II to
type 1 angiotensin (AT1) receptors. They reduce angiotensin II-induced
vasoconstriction, sodium reabsorption and aldosterone release. They also reduce the
effect of angiotensin II on sympathetic nervous activity and growth factors.
sartans therapeutic indication - Answer hypertension
sartans side effects - Answer - Dizziness
- Headache
- Hyperkalaemia
Calcium channel blockers (dihydropyridines)- active ingredient - Answer Amlodipine,
Clevidipine, Felodipine.
calcium channel blockers suffix - Answer -dipine
calcium channel blockers mechanism of action - Answer Block inward current of
calcium into cells in vascular smooth muscle, myocardium, and cardiac conducting
system via L-type calcium channels.
calcium channel blockers therapeutic indications - Answer Hypertension, Angina
calcium channel blockers side effects - Answer may increase risk of muscle weakness
and respiratory depression, - Nausea
- Vasodilatory effects including:
- Headache
- Flushing
- Dizziness
- Hypotension
- Peripheral oedema
Calcium Channel Blockers (non-dihydropyridines) active ingredient - Answer Diltiazem,
verapamil, Trandolapril with verapamil
Calcium Channel Blockers (non-dihydropyridines) suffix - Answer -il
Beta Blockers- active ingredient/ drug name - Answer Atenolol, Bisoprolol, Carvedilol
Beta blockers suffix - Answer -olol
beta blockers Mechanism of action - Answer Competitively block beta receptors, reduce
heart rate, BP, and cardiac contractility
beta blockers Therapeutic Indications - Answer Common uses include a range of
cardiovascular conditions (e.g. hypertension, angina, MI, tachyarrhythmias, heart
failure) and the prevention of migraine.
beta blockers side effects - Answer - bradycardia
- hypotension
- orthostatic hypotension (especially carvedilol, labetalol)
- transient worsening of heart failure (when treatment starts)
- nausea
- diarrhoea
ACE Inhibitors- active ingredient - Answer (Angiotensin Converting Enzyme Inhibitors)-
Perindopril, Captopril, Enalapril
ACE Inhibitors suffix - Answer -pril
ACE inhibitor Mechanism of action - Answer block conversion of angiotensin I to
angiotensin II and also inhibit the breakdown of bradykinin.
ACE inhibitors therapeutic indicators - Answer Hypertension, Chronic heart failure with
reduced ejection fraction as part of standard treatment. Diabetic nephropathy.
Prevention of progressive renal failure in patients with persistent proteinuria (>1 g
daily). Post MI.
ACE inhibitors side effects - Answer - hypotension
- headache
- dizziness
- cough
- Hyperkalaemia
- Fatigue
, - Nausea
- Renal impairment
Sartans- active ingredient - Answer Candesartan, Eprosartan, Irbesartan
sartans- suffix - Answer -sartan
sartans mechanism of action - Answer Competitively block binding of angiotensin II to
type 1 angiotensin (AT1) receptors. They reduce angiotensin II-induced
vasoconstriction, sodium reabsorption and aldosterone release. They also reduce the
effect of angiotensin II on sympathetic nervous activity and growth factors.
sartans therapeutic indication - Answer hypertension
sartans side effects - Answer - Dizziness
- Headache
- Hyperkalaemia
Calcium channel blockers (dihydropyridines)- active ingredient - Answer Amlodipine,
Clevidipine, Felodipine.
calcium channel blockers suffix - Answer -dipine
calcium channel blockers mechanism of action - Answer Block inward current of
calcium into cells in vascular smooth muscle, myocardium, and cardiac conducting
system via L-type calcium channels.
calcium channel blockers therapeutic indications - Answer Hypertension, Angina
calcium channel blockers side effects - Answer may increase risk of muscle weakness
and respiratory depression, - Nausea
- Vasodilatory effects including:
- Headache
- Flushing
- Dizziness
- Hypotension
- Peripheral oedema
Calcium Channel Blockers (non-dihydropyridines) active ingredient - Answer Diltiazem,
verapamil, Trandolapril with verapamil
Calcium Channel Blockers (non-dihydropyridines) suffix - Answer -il
