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Exam (elaborations)

CSB601 Exam Study Set @ 2024

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CSB601 Exam Study Set @ 2024
What is the current the current healthcare model? - Answer Reactive healthcare -
healthcare provided on symptoms

Predictive Healthcare - Answer - take into account genes and biology, environments and
lifestyles

- analyses range of data to achieve outcome including clinical observations,
biomarkers, pt generated data

Data analysis in healthcare - Answer - personalised prevention plans

- early diagnosis

- personalised treatment plans

Benefits of PM - Answer - pt-centeredness

- prevention to minimise disease onset

- better diagnosis

-early intervention

- personalised med tailored to a specific pt

- potential to reduce health costs

Facets of PM - Answer multimodal system

- clinical test

- imaging

- digital health

- omics and biomarkers

- computational health

- micro biome info

- behaviour and lifestyle

Complementary meds - Answer PICO questions to determine if CM is useful for pts

Population

Intervention

,Comparison/control

Outcome

CM use - Answer - safe

- effective

- appropriate

- judicious/wise

PEACE - Answer for CM decision making process

- Personal preference

- Evidence

- Alternative

- Costs and risks vs benefits

- Expedience e.g availability, accessibility, and immediacy of treatment

BEECH - Answer principles of integrative and holistic medicine

- Balance

- Empowerment

- Evidence-based care

- Collaboration

- Holism (health is multi-dimesional)

Best database for CM - Answer Natural medicines database (NATMED)

CM key information for use - Answer dose, strength, indication, purpose, and who
prescribed it

- 1st step: safety first, side effects, interactions, reliability, safety, quality

- 2nd step: evidence of efficacy, knowledge of resources and databases, education

Antimicrobials - Answer Infection: invasion of body by microorganisms causing disease
by local cellular injury

types: antibacterial, antivirals, anti fun gals, antiprotozoals, anthelmintics

MOA for antimicrobials - Answer attacks the difference between bacteria and human
cells

, antimicrobial resistance - Answer resistance and passing resistant genes b/w or within
bacteria

Antimicrobial stewardship (AMS) - Answer improve the safe and appropriate use of
antimicrobials to reduce pt harm, prevent antimicrobial resistance. It is required in
hospital

Allergies (types of reactions) - Answer unpredictable

immediate: IgE-mediated within minutes-2 hours

delayed: T-cells mediated within days

severe delay: uncommon but serious

desensitisation: allergy or an ADR?

AntiBiotic (AB) drug: AMINOGLYCOSIDES - Answer E.G: gentamicin, tobramycin (cin)

Contras:

- elder - caution

- child & pregnancy - specialist advice

- renal - reduce dose with impairment

- caution - obesity, burns, CF, trauma, ICU, patients, neuromuscular disease,
hypopcalcaemia, hypermagnesaemia, GA, blood transfusions

AB drug: CARBAPENEMS - Answer E.G: meropenem, (penem)

binds to penicillin-binding proteins

for mod-severe infections (meningitis, diabetic foot etc)

Contras:

elder - dizziness, confusion

hep - can alter LFT

pregnancy -limited info

renal - reduce dose

caution - pennecillin allergy, seizures, sodium restriction

AB drug: CEPHALOSPORINS - Answer E.G: ceftriaxone, cefepome (cef)

rarely first line

mod-broad spectrum

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