CSB601 Exam Study Set @ 2024
What is the current the current healthcare model? - Answer Reactive healthcare -
healthcare provided on symptoms
Predictive Healthcare - Answer - take into account genes and biology, environments and
lifestyles
- analyses range of data to achieve outcome including clinical observations,
biomarkers, pt generated data
Data analysis in healthcare - Answer - personalised prevention plans
- early diagnosis
- personalised treatment plans
Benefits of PM - Answer - pt-centeredness
- prevention to minimise disease onset
- better diagnosis
-early intervention
- personalised med tailored to a specific pt
- potential to reduce health costs
Facets of PM - Answer multimodal system
- clinical test
- imaging
- digital health
- omics and biomarkers
- computational health
- micro biome info
- behaviour and lifestyle
Complementary meds - Answer PICO questions to determine if CM is useful for pts
Population
Intervention
,Comparison/control
Outcome
CM use - Answer - safe
- effective
- appropriate
- judicious/wise
PEACE - Answer for CM decision making process
- Personal preference
- Evidence
- Alternative
- Costs and risks vs benefits
- Expedience e.g availability, accessibility, and immediacy of treatment
BEECH - Answer principles of integrative and holistic medicine
- Balance
- Empowerment
- Evidence-based care
- Collaboration
- Holism (health is multi-dimesional)
Best database for CM - Answer Natural medicines database (NATMED)
CM key information for use - Answer dose, strength, indication, purpose, and who
prescribed it
- 1st step: safety first, side effects, interactions, reliability, safety, quality
- 2nd step: evidence of efficacy, knowledge of resources and databases, education
Antimicrobials - Answer Infection: invasion of body by microorganisms causing disease
by local cellular injury
types: antibacterial, antivirals, anti fun gals, antiprotozoals, anthelmintics
MOA for antimicrobials - Answer attacks the difference between bacteria and human
cells
, antimicrobial resistance - Answer resistance and passing resistant genes b/w or within
bacteria
Antimicrobial stewardship (AMS) - Answer improve the safe and appropriate use of
antimicrobials to reduce pt harm, prevent antimicrobial resistance. It is required in
hospital
Allergies (types of reactions) - Answer unpredictable
immediate: IgE-mediated within minutes-2 hours
delayed: T-cells mediated within days
severe delay: uncommon but serious
desensitisation: allergy or an ADR?
AntiBiotic (AB) drug: AMINOGLYCOSIDES - Answer E.G: gentamicin, tobramycin (cin)
Contras:
- elder - caution
- child & pregnancy - specialist advice
- renal - reduce dose with impairment
- caution - obesity, burns, CF, trauma, ICU, patients, neuromuscular disease,
hypopcalcaemia, hypermagnesaemia, GA, blood transfusions
AB drug: CARBAPENEMS - Answer E.G: meropenem, (penem)
binds to penicillin-binding proteins
for mod-severe infections (meningitis, diabetic foot etc)
Contras:
elder - dizziness, confusion
hep - can alter LFT
pregnancy -limited info
renal - reduce dose
caution - pennecillin allergy, seizures, sodium restriction
AB drug: CEPHALOSPORINS - Answer E.G: ceftriaxone, cefepome (cef)
rarely first line
mod-broad spectrum
What is the current the current healthcare model? - Answer Reactive healthcare -
healthcare provided on symptoms
Predictive Healthcare - Answer - take into account genes and biology, environments and
lifestyles
- analyses range of data to achieve outcome including clinical observations,
biomarkers, pt generated data
Data analysis in healthcare - Answer - personalised prevention plans
- early diagnosis
- personalised treatment plans
Benefits of PM - Answer - pt-centeredness
- prevention to minimise disease onset
- better diagnosis
-early intervention
- personalised med tailored to a specific pt
- potential to reduce health costs
Facets of PM - Answer multimodal system
- clinical test
- imaging
- digital health
- omics and biomarkers
- computational health
- micro biome info
- behaviour and lifestyle
Complementary meds - Answer PICO questions to determine if CM is useful for pts
Population
Intervention
,Comparison/control
Outcome
CM use - Answer - safe
- effective
- appropriate
- judicious/wise
PEACE - Answer for CM decision making process
- Personal preference
- Evidence
- Alternative
- Costs and risks vs benefits
- Expedience e.g availability, accessibility, and immediacy of treatment
BEECH - Answer principles of integrative and holistic medicine
- Balance
- Empowerment
- Evidence-based care
- Collaboration
- Holism (health is multi-dimesional)
Best database for CM - Answer Natural medicines database (NATMED)
CM key information for use - Answer dose, strength, indication, purpose, and who
prescribed it
- 1st step: safety first, side effects, interactions, reliability, safety, quality
- 2nd step: evidence of efficacy, knowledge of resources and databases, education
Antimicrobials - Answer Infection: invasion of body by microorganisms causing disease
by local cellular injury
types: antibacterial, antivirals, anti fun gals, antiprotozoals, anthelmintics
MOA for antimicrobials - Answer attacks the difference between bacteria and human
cells
, antimicrobial resistance - Answer resistance and passing resistant genes b/w or within
bacteria
Antimicrobial stewardship (AMS) - Answer improve the safe and appropriate use of
antimicrobials to reduce pt harm, prevent antimicrobial resistance. It is required in
hospital
Allergies (types of reactions) - Answer unpredictable
immediate: IgE-mediated within minutes-2 hours
delayed: T-cells mediated within days
severe delay: uncommon but serious
desensitisation: allergy or an ADR?
AntiBiotic (AB) drug: AMINOGLYCOSIDES - Answer E.G: gentamicin, tobramycin (cin)
Contras:
- elder - caution
- child & pregnancy - specialist advice
- renal - reduce dose with impairment
- caution - obesity, burns, CF, trauma, ICU, patients, neuromuscular disease,
hypopcalcaemia, hypermagnesaemia, GA, blood transfusions
AB drug: CARBAPENEMS - Answer E.G: meropenem, (penem)
binds to penicillin-binding proteins
for mod-severe infections (meningitis, diabetic foot etc)
Contras:
elder - dizziness, confusion
hep - can alter LFT
pregnancy -limited info
renal - reduce dose
caution - pennecillin allergy, seizures, sodium restriction
AB drug: CEPHALOSPORINS - Answer E.G: ceftriaxone, cefepome (cef)
rarely first line
mod-broad spectrum